A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

ClinicalTrials.gov ID: NCT07428616

Public ClinicalTrials.gov record NCT07428616. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Single-Arm, Multicenter, Open-Label Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objective of the study is to evaluate efficacy and safety of zanzalintinib in participants with recurrent or progressive meningioma refractory to standard therapies.

Study identification

NCT ID: NCT07428616
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Exelixis; Industry
Enrollment: 100 participants

Conditions and interventions

Conditions

Meningioma

Interventions

Zanzalintinib Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 21, 2026 (Actual)
Primary completion: Feb 29, 2028 (Estimated)
Completion: Sep 30, 2029 (Estimated)
Last update posted: Oct 6, 2026

2026 – 2029

United States locations

U.S. sites: 19
U.S. states: 15
U.S. cities: 19

Facility	City	State	ZIP	Site status
University of Alabama	Birmingham	Alabama	35294	Recruiting
Mayo Clinic_Arizona	Phoenix	Arizona	85054	Recruiting
Providence - Saint John's Health Center	Santa Monica	California	90404	Recruiting
Mayo Clinic_Jacksonville	Jacksonville	Florida	32224	Recruiting
Baptist Health Miami Cancer Institute	Miami	Florida	33176	Recruiting
Tampa General Hospital	Tampa	Florida	33619	Recruiting
Northwestern University	Chicago	Illinois	60611	Recruiting
LSU Health Science Center	New Orleans	Louisiana	70112	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Memorial Sloan-Kettering Cancer Center	New York	New York	10065	Recruiting
Mayo Clinic_Rochester	Rochester	New York	55905	Recruiting
Duke University	Durham	North Carolina	27710	Recruiting
The Ohio State University College of Medicine (OSUCOM)	Columbus	Ohio	43210	Recruiting
Brown University Health Cancer Institute	Providence	Rhode Island	02903	Recruiting
UT MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
UT Health San Antonio Mays Cancer Center	San Antonio	Texas	78229	Recruiting
Inova Center for Personalized Health	Fairfax	Virginia	22031	Recruiting
UW Carbone Cancer Center	Madison	Wisconsin	53792	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07428616, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 6, 2026 · Synced Oct 21, 2026

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The complete public registry record, listed eligibility criteria, and available contact information for NCT07428616 live on ClinicalTrials.gov.

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