A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

ClinicalTrials.gov ID: NCT07441252

Public ClinicalTrials.gov record NCT07441252. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2b Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety and Tolerability of Maridebart Cafraglutide in Adult Participants Living With Elevated Liver Fat and Obesity or Overweight

Study identification

NCT ID: NCT07441252
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Amgen; Industry
Enrollment: 180 participants

Conditions and interventions

Conditions

Overweight or Obesity and Elevated Liver Fat

Interventions

Maridebart cafraglutide Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 99 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 4, 2026
Primary completion: Sep 28, 2027
Completion: Dec 21, 2027
Last update posted: May 4, 2026

2026 – 2027

United States locations

U.S. sites: 18
U.S. states: 6
U.S. cities: 17

Facility	City	State	ZIP	Site status
Arizona Clinical Trials	Chandler	Arizona	85224	Recruiting
Medical Advancement Centers of Arizona	Phoenix	Arizona	85044	Recruiting
Gastroenterology and Liver Institute	Escondido	California	92025	Recruiting
Inland Empire Liver Foundation	Rialto	California	92377	Recruiting
Apex Clinical Research	San Diego	California	92120	Recruiting
University of Florida College of Medicine-Jacksonville	Gainesville	Florida	32610	Recruiting
Indago Research and Health Center	Hialeah	Florida	33012	Recruiting
Floridian Clinical Research LLC	Miami Lakes	Florida	33016	Recruiting
Woodholme Gastroenterology Associates - Glen Burnie	Glen Burnie	Maryland	21061	Recruiting
Excel Clinical Research	Las Vegas	Nevada	89109	Recruiting
Juno Research LLC	Bellaire	Texas	77401	Recruiting
Pinnacle Clinical Research - Corpus Christi	Corpus Christi	Texas	78404	Recruiting
South Texas Research Institute	Edinburg	Texas	78539	Recruiting
Houston Research Institute	Houston	Texas	77079	Recruiting
Houston Research Institute - Pasadena	Pasadena	Texas	77505	Recruiting
McAllen Research	Pharr	Texas	78557	Recruiting
American Research Corporation at the Texas Liver Institute	San Antonio	Texas	78215	Recruiting
Pinnacle Clinical Research	San Antonio	Texas	78229	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07441252, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 4, 2026 · Synced May 6, 2026

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The complete protocol, eligibility criteria, and contact information for NCT07441252 live on ClinicalTrials.gov.

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