A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight
Public ClinicalTrials.gov record NCT07441252. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2b Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety and Tolerability of Maridebart Cafraglutide in Adult Participants Living With Elevated Liver Fat and Obesity or Overweight
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main objective of this trial will be to determine whether maridebart cafraglutide is superior to placebo on reduction in liver fat content and body weight in participants living with obesity or overweight and elevated liver fat content, when administered in conjunction with reduced-calorie diet and increased physical activity.
Study identification
- NCT ID
- NCT07441252
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 180 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 5, 2026 (Actual)
- Primary completion
- Aug 25, 2027 (Estimated)
- Completion
- Nov 17, 2027 (Estimated)
- Last update posted
- Sep 28, 2026
2026 – 2027
United States locations
- U.S. sites
- 23
- U.S. states
- 8
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Clinical Trials | Chandler | Arizona | 85224 | — |
| Medical Advancement Centers of Arizona | Phoenix | Arizona | 85044 | — |
| Del Sol Research Management | Tucson | Arizona | 85715 | — |
| San Fernando Valley Health Institute | Canoga Park | California | 91304 | — |
| Gastroenterology and Liver Institute | Escondido | California | 92025 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| Apex Clinical Research | San Diego | California | 92120 | — |
| University of Florida College of Medicine-Jacksonville | Gainesville | Florida | 32610 | — |
| Floridian Clinical Research LLC | Miami Lakes | Florida | 33016 | — |
| Indago Research and Health Center | Miami Lakes | Florida | 33016 | — |
| Gastrointestinal Specialists- Louisiana Research Center- Highland | Shreveport | Louisiana | 71105 | — |
| Woodholme Gastroenterology Associates - Glen Burnie | Glen Burnie | Maryland | 21061 | — |
| Alliance for Multispecialty Research - Kansas City | Kansas City | Missouri | 64114 | — |
| Excel Clinical Research | Las Vegas | Nevada | 89109 | — |
| Bellaire Clinical Research | Bellaire | Texas | 77401 | — |
| Juno Research LLC | Bellaire | Texas | 77401 | — |
| Pinnacle Clinical Research - Corpus Christi | Corpus Christi | Texas | 78404 | — |
| South Texas Research Institute | Edinburg | Texas | 78539 | — |
| Houston Research Institute | Houston | Texas | 77079 | — |
| Houston Research Institute - Pasadena | Pasadena | Texas | 77505 | — |
| McAllen Research | Pharr | Texas | 78557 | — |
| American Research Corporation at the Texas Liver Institute | San Antonio | Texas | 78215 | — |
| Pinnacle Clinical Research | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07441252, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07441252 live on ClinicalTrials.gov.