CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
Public ClinicalTrials.gov record NCT07449923. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Prospective, Randomized, Double-Masked, Parallel-Group Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept (2 mg) in Participants With Diabetic Macular Edema (DME)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.
Study identification
- NCT ID
- NCT07449923
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 240 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 9, 2026 (Actual)
- Primary completion
- Oct 2027 (Estimated)
- Completion
- Oct 2028 (Estimated)
- Last update posted
- Oct 2, 2026
2026 – 2028
United States locations
- U.S. sites
- 51
- U.S. states
- 24
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultans | Gilbert | Arizona | 85297 | — |
| Associated Retina Consultants - Phoenix | Phoenix | Arizona | 85020 | — |
| Phoenix Retina Clinical Trials, LLC - North Phoenix | Phoenix | Arizona | 85050 | — |
| Retina Macula Institute of Arizona | Scottsdale | Arizona | 85255 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| South Coast Retina Center | Long Beach | California | 90807 | — |
| Retinal Consultants Medical Group - Modesto | Modesto | California | 95356 | — |
| Kaiser Permanente | Oakland | California | 94611 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Retina Specialists of Colorado - Arvada | Arvada | Colorado | 80002 | — |
| Connecticut Eye Consultants, P.C. | Danbury | Connecticut | 06810 | — |
| Coastal Eye Surgeons, LLC | Greenwich | Connecticut | 06830 | — |
| Retina Group of New England, PC | Waterford | Connecticut | 06385 | — |
| Retina Group of Florida - Fort Lauderdale | Fort Lauderdale | Florida | 33308 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| MedEye Associates | South Miami | Florida | 33143 | — |
| Retina Vitreous Associates of Florida - Saint Petersburg | St. Petersburg | Florida | 33711 | — |
| Retina Vitreous Associates of Florida | Tampa | Florida | 33617 | — |
| Retina Associates | Elmhurst | Illinois | 60126 | — |
| University Retina and Macula Associates | Lemont | Illinois | 60439 | — |
| Illinois Retina Associates, S.C. | Oak Park | Illinois | 60304 | — |
| Associated Vitreoretinal & Uveitis Consultants - Carmel | Carmel | Indiana | 46032 | — |
| The Eye Care Institute | Louisville | Kentucky | 40206 | — |
| Retina Associates New Orleans | Metairie | Louisiana | 70006 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Mid Atlantic Retina Specialists - Hagerstown | Hagerstown | Maryland | 21740 | — |
| Vitreo Retinal Associates, PC | Worcester | Massachusetts | 01605 | — |
| The Retina Institute | St Louis | Missouri | 63128 | — |
| Retina Center of New Jersey | Bloomfield | New Jersey | 07003 | — |
| Vision Research Center at Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Retina Vitreous Surgeons of CNY, PC | Liverpool | New York | 13088 | — |
| Graystone Eye - Hickory Office | Hickory | North Carolina | 28602 | — |
| North Carolina Retina Associates | Wake Forest | North Carolina | 27587 | — |
| Retina Vitreous Center, PLLC | Edmond | Oklahoma | 73013 | — |
| Verum Research, LLC | Eugene | Oregon | 97401 | — |
| Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Carolinas Centers for Sight, P.C. - Florence Campus | Florence | South Carolina | 29501 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| Retina and Vitreous of Texas | Bellaire | Texas | 77401 | — |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | — |
| San Antonio Eye Center | San Antonio | Texas | 78215 | — |
| Retina Associates of South Texas | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384 | — |
| Tyler Retina Consultants | Tyler | Texas | 75703 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| The Retina Group of Washington | Fairfax | Virginia | 22031 | — |
| Eye Clinic of Wisconsin | Wausau | Wisconsin | 54403 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07449923, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 2, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07449923 live on ClinicalTrials.gov.