A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Public ClinicalTrials.gov record NCT07463183. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-8690 in Adult Participants With Moderately to Severely Active Ulcerative Colitis
Study identification
- NCT ID
- NCT07463183
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Interventions
- MK-8690 Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 23, 2026
- Primary completion
- Oct 27, 2027
- Completion
- Dec 20, 2028
- Last update posted
- Apr 20, 2026
2026 – 2028
United States locations
- U.S. sites
- 7
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinnova Research ( Site 1042) | Anaheim | California | 92805 | Recruiting |
| Peak Gastroenterology Associates ( Site 1052) | Colorado Springs | Colorado | 80907 | Recruiting |
| South Denver Gastroenterology, PC ( Site 1068) | Englewood | Colorado | 80113 | Recruiting |
| Nature Coast Clinical Research ( Site 1045) | Inverness | Florida | 34452 | Recruiting |
| Research Associates of South Florida - Miami - Southwest 8th Street ( Site 1072) | Miami | Florida | 33134 | Recruiting |
| Gastroenterology Associates of Central Georgia ( Site 1060) | Macon | Georgia | 31201 | Recruiting |
| BVL Research - Kansas ( Site 1054) | Liberty | Missouri | 64068 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07463183, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07463183 live on ClinicalTrials.gov.