Clinical Trials Finder
Independent ClinicalTrials.gov directory
ClinicalTrials.gov record
Recruiting Phase 3 Interventional

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

ClinicalTrials.gov ID: NCT07482176

Public ClinicalTrials.gov record NCT07482176. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search
ClinicalTrials.gov public records Last synced May 20, 2026, 11:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-center, Randomized, Double-masked, Active-comparator-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Study identification

NCT ID
NCT07482176
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Adverum Biotechnologies, Inc.
Industry
Enrollment
284 participants

Conditions and interventions

Interventions

  • Aflibercept Drug
  • Ixo-vec Genetic

Drug · Genetic

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 15, 2026
Primary completion
Nov 14, 2027
Completion
Oct 19, 2031
Last update posted
May 19, 2026

2026 – 2031

United States locations

U.S. sites
46
U.S. states
15
U.S. cities
41
Facility City State ZIP Site status
Adverum Clinical Site 126 Phoenix Arizona 85014 Recruiting
Adverum Clinical Site 178 Phoenix Arizona 85020 Recruiting
Adverum Clinical Site 223 Phoenix Arizona 85020 Recruiting
Adverum Clinical Site 229 Scottsdale Arizona 85255 Recruiting
Adverum Clinical Site 198 Springdale Arkansas 72764 Recruiting
Adverum Clinical Site 109 Bakersfield California 93309 Recruiting
Adverum Clinical Site 100 Beverly Hills California 90211 Recruiting
Adverum Clinical Site 201 Campbell California 95008 Recruiting
Adverum Clinical Site 172 Encino California 91436 Recruiting
Adverum Clinical Site 169 Fullerton California 92835 Recruiting
Adverum Clinical Site 224 Huntington Beach California 92647 Recruiting
Adverum Clinical Site 215 Redlands California 92374 Recruiting
Adverum Clinical Site 140 Sacramento California 95825 Recruiting
Adverum Clinical Site 212 Sacramento California 95841 Recruiting
Adverum Clinical Site 202 Torrance California 90503 Recruiting
Adverum Clinical Site 189 Walnut Creek California 94598 Recruiting
Adverum Clinical Site 116 Denver Colorado 80207 Recruiting
Adverum Clinical Site 165 Waterford Connecticut 06385 Recruiting
Adverum Clinical Site 124 Deerfield Beach Florida 33064 Recruiting
Adverum Clinical Site 184 Deerfield Beach Florida 33064 Recruiting
Adverum Clinical Site 176 Fort Lauderdale Florida 33308 Recruiting
Adverum Clinical Site 221 Fort Myers Florida 33912 Recruiting
Adverum Clinical Site 214 Lakeland Florida 33805 Recruiting
Adverum Clinical Site 213 Orlando Florida 32806 Recruiting
Adverum Clinical Site 183 South Miami Florida 33143 Recruiting
Adverum Clinical Site 182 Augusta Georgia 30909 Recruiting
Adverum Clinical Site 195 Carmel Indiana 46032 Recruiting
Adverum Clinical Site 204 Hagerstown Maryland 21740 Recruiting
Adverum Clinical Site 216 Jackson Mississippi 39202 Recruiting
Adverum Clinical Site 225 Liverpool New York 13088 Recruiting
Adverum Clinical Site 196 Asheville North Carolina 28803 Recruiting
Adverum Clinical Site 211 Greensboro North Carolina 27401 Recruiting
Adverum Clinical Site 219 Greensboro North Carolina 27401 Recruiting
Adverum Clinical Site 220 Hickory North Carolina 28602 Recruiting
Adverum Clinical Site 209 Wake Forest North Carolina 27587 Recruiting
Adverum Clinical Site 241 Bluffton South Carolina 29910 Recruiting
Adverum Clinical Site 222 Ladson South Carolina 29456 Recruiting
Adverum Clinical Site 127 Austin Texas 78705 Recruiting
Adverum Clinical Site 107 Conroe Texas 77384 Recruiting
Adverum Clinical Site 194 Dallas Texas 75231 Recruiting
Adverum Clinical Site 162 McAllen Texas 78503 Recruiting
Adverum Clinical Site 232 San Marcos Texas 78666 Recruiting
Adverum Clinical Site 228 Schertz Texas 78154 Recruiting
Adverum Clinical Site 231 The Woodlands Texas 77384 Recruiting
Adverum Clinical Site 237 Tyler Texas 75703 Recruiting
Adverum Clinical Site 199 Lynchburg Virginia 24502 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07482176, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 19, 2026 · Synced May 20, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07482176 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →