Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
Public ClinicalTrials.gov record NCT07484217. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-blind, Placebo-controlled, Randomized Withdrawal Study of Solriamfetol in Subjects With Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal trial in patients with major depressive disorder (MDD) with excessive daytime sleepiness (EDS) symptoms consisting of an open-label solriamfetol treatment period and a randomized, double-blind treatment period.
Study identification
- NCT ID
- NCT07484217
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 508 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 23, 2026 (Actual)
- Primary completion
- Dec 2028 (Estimated)
- Completion
- Dec 2028 (Estimated)
- Last update posted
- Oct 13, 2026
2026 – 2028
United States locations
- U.S. sites
- 40
- U.S. states
- 15
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site | Tucson | Arizona | 85704 | Recruiting |
| Clinical Research Site | Bellflower | California | 90706 | Recruiting |
| Clinical Research Site | Chino | California | 91710 | Recruiting |
| Clinical Research Site | Glendale | California | 91206 | Recruiting |
| Clinical Research Site | Imperial | California | 92251 | Recruiting |
| Clinical Research Site | Los Angeles | California | 90015 | Recruiting |
| Clinical Research Site | Oceanside | California | 92056 | Recruiting |
| Clinical Research Site | Redlands | California | 92374 | Recruiting |
| Clinical Research Site | San Diego | California | 92123 | Recruiting |
| Clinical Research Site | Sherman Oaks | California | 91403 | Recruiting |
| Clinical Research Site | Walnut Creek | California | 94596 | Recruiting |
| Clinical Research Site | Jacksonville | Florida | 32256 | Recruiting |
| Clinical Research Site | Miami | Florida | 33122 | Recruiting |
| Clinical Research Site | Miami | Florida | 33176 | Recruiting |
| Clinical Research Site | Atlanta | Georgia | 30331 | Recruiting |
| Clinical Research Site | Norcross | Georgia | 30092 | Recruiting |
| Clinical Research Site | Snellville | Georgia | 30078 | Recruiting |
| Clinical Research Site | Chicago | Illinois | 60634 | Recruiting |
| Clinical Research Site | Pikesville | Maryland | 21208 | Recruiting |
| Clinical Research Site | Springfield | Massachusetts | 01103 | Recruiting |
| Clinical Research Site | Las Vegas | Nevada | 89102 | Recruiting |
| Clinical Research Site | Las Vegas | Nevada | 89119 | Recruiting |
| Clinical Research Site | Cherry Hill | New Jersey | 08002 | Recruiting |
| Clinical Research Site | Toms River | New Jersey | 08755 | Recruiting |
| Clinical Research Site | Brooklyn | New York | 11235 | Recruiting |
| Clinical Research Site | New York | New York | 10036 | Recruiting |
| Clinical Research Site | New York | New York | 10128 | Recruiting |
| Clinical Research Site | Staten Island | New York | 10314 | Recruiting |
| Clinical Research Site | The Bronx | New York | 10464 | Recruiting |
| Clinical Research Site | Cincinnati | Ohio | 45215 | Recruiting |
| Clinical Research Site | Cincinnati | Ohio | 45245 | Recruiting |
| Clinical Research Site | Edmond | Oklahoma | 73013 | Recruiting |
| Clinical Research Site | Oklahoma City | Oklahoma | 73116 | Recruiting |
| Clinical Research Site | Portland | Oregon | 97210 | Recruiting |
| Clinical Research Site | Memphis | Tennessee | 38119 | Recruiting |
| Clinical Research Site | Austin | Texas | 78759 | Recruiting |
| Clinical Research Site | Bellaire | Texas | 77401 | Recruiting |
| Clinical Research Site | Dallas | Texas | 75243 | Recruiting |
| Clinical Research Site | Houston | Texas | 77007 | Recruiting |
| Clinical Research Site | San Antonio | Texas | 78240 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07484217, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 13, 2026 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07484217 live on ClinicalTrials.gov.