A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
Public ClinicalTrials.gov record NCT07491458. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Parallel Treatment Group, Phase 2a, Double-blind, 4-arm Trial to Evaluate the Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Male and Female Participants Aged 30 Years or Older With Metabolic Dysfunction-associated Steatohepatitis (MASH)
Study identification
- NCT ID
- NCT07491458
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Rivus Pharmaceuticals, Inc.
- Industry
- Enrollment
- 180 participants
Conditions and interventions
Interventions
- HU6 Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 30 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 12, 2026
- Primary completion
- Jan 31, 2027
- Completion
- Jan 31, 2028
- Last update posted
- May 17, 2026
2026 – 2028
United States locations
- U.S. sites
- 31
- U.S. states
- 15
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Liver Health - Chandler | Chandler | Arizona | 85224 | Recruiting |
| Arizona Liver Health - Peoria | Peoria | Arizona | 85381 | Recruiting |
| Arizona Liver Health - Tucson | Tucson | Arizona | 85712 | Recruiting |
| Baptist Health Center for Clinical Research | Little Rock | Arkansas | 72205 | Recruiting |
| National Institute of Clinical Research | Garden Grove | California | 92844 | Recruiting |
| Catalina Research Institute | Montclair | California | 91763 | Recruiting |
| Knowledge Research Center | Orange | California | 92868 | Recruiting |
| Charter Research LLC - Orlando | Orlando | Florida | 32803 | Recruiting |
| Charter Research LLC - Chicago | Chicago | Illinois | 60618 | Recruiting |
| Delta Research Partners of Bastrop, LLC | Bastrop | Louisiana | 71220 | Recruiting |
| Delta Research Partners of West Monroe, LLC | West Monroe | Louisiana | 71291 | Recruiting |
| Clinical Research Institute of Michigan | Clinton Township | Michigan | 48038 | Recruiting |
| Nucleus Network Minneapolis | Saint Paul | Minnesota | 55114 | Recruiting |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | Recruiting |
| KAD Clinical Research | St Louis | Missouri | 63123 | Recruiting |
| Jubilee Clinical Research, LLC. | Las Vegas | Nevada | 89106 | Recruiting |
| Coastal Research Institute | Fayetteville | North Carolina | 28304 | Recruiting |
| Clinical Research Institute of Ohio, LLC (CRIOH) | Westlake | Ohio | 44145 | Recruiting |
| Tekton Research - Yukon | Yukon | Oklahoma | 73099 | Recruiting |
| Innovative Clinical Research, LLC | Clarksville | Tennessee | 37040 | Recruiting |
| IMA Clinical Research (Austin) | Austin | Texas | 78745 | Recruiting |
| Pinnacle Clinical Research - Austin | Austin | Texas | 78757 | Recruiting |
| Bellaire Clinical Research, LLC | Bellaire | Texas | 77401 | Recruiting |
| Pinnacle Clinical Research - Corpus Christi | Corpus Christi | Texas | 78404 | Recruiting |
| Pinnacle Clinical Research - Georgetown | Georgetown | Texas | 78626 | Recruiting |
| HRI - Medical Center, LLC | Houston | Texas | 77030 | Recruiting |
| Houston Research Institute | Houston | Texas | 77079 | Recruiting |
| HRI - Pasadena, LLC | Pasadena | Texas | 77505 | Recruiting |
| Quality Research | San Antonio | Texas | 78209 | Recruiting |
| Pinnacle Clinical Research - San Antonio | San Antonio | Texas | 78229 | Recruiting |
| HRI - Sugarland, LLC | Sugar Land | Texas | 77478 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07491458, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 17, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07491458 live on ClinicalTrials.gov.