A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Public ClinicalTrials.gov record NCT07492680. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Open-Label, Multi-Center Study of BMS-986504 as Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an open-label, multicenter Phase 2 study evaluating BMS-986504 in participants with advanced and/or metastatic solid tumors that have MTAP deletion. The study includes a monotherapy component and a combination component in which BMS-986504 is given with other anti-cancer agents. The trial will assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of BMS-986504 alone and in combination regimens.
Study identification
- NCT ID
- NCT07492680
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 260 participants
Conditions and interventions
Conditions
Interventions
- BMS-986504 Drug
- Daraxonrasib Drug
- Nivolumab + Relatlimab FDC Drug
- Temozolomide Drug
- Pumitamig Drug
- Pemetrexed Drug
- Carboplatin Drug
- Nab-paclitaxel Drug
- Gemcitabine Drug
- Paclitaxel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 26, 2026
- Primary completion
- Aug 14, 2028
- Completion
- May 19, 2032
- Last update posted
- Aug 24, 2026
2026 – 2032
United States locations
- U.S. sites
- 16
- U.S. states
- 12
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0096 | San Francisco | California | 94158 | Not yet recruiting |
| Local Institution - 0182 | Aurora | Colorado | 80045 | Not yet recruiting |
| Local Institution - 0178 | Atlanta | Georgia | 30322 | Not yet recruiting |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | Recruiting |
| Local Institution - 0124 | Boston | Massachusetts | 02114 | Not yet recruiting |
| Local Institution - 0119 | Ann Arbor | Michigan | 48109-0922 | Not yet recruiting |
| Local Institution - 0129 | Rochester | Minnesota | 55905 | Not yet recruiting |
| Local Institution - 0174 | Rochester | Minnesota | 55905 | Not yet recruiting |
| Local Institution - 0181 | Rochester | Minnesota | 55905 | Not yet recruiting |
| Local Institution - 0142 | Buffalo | New York | 14263 | Not yet recruiting |
| Local Institution - 0170 | New York | New York | 10016 | Not yet recruiting |
| Local Institution - 0139 | New York | New York | 10065 | Not yet recruiting |
| Local Institution - 0100 | Durham | North Carolina | 27705 | Not yet recruiting |
| Local Institution - 0085 | Houston | Texas | 77030 | Not yet recruiting |
| Local Institution - 0086 | Seattle | Washington | 98109 | Not yet recruiting |
| Local Institution - 0134 | Madison | Wisconsin | 53792 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07492680, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07492680 live on ClinicalTrials.gov.