A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
Public ClinicalTrials.gov record NCT07496567. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Double-masked, Multicenter, 3-arm, Pivotal Phase 2/3 Study to Evaluate the Efficacy and Safety of Intravitreal (IVT) EYE201/MK-8748 Compared to Aflibercept (2 mg) in Participants With Neovascular Age-related Macular Degeneration (NVAMD)
Study identification
- NCT ID
- NCT07496567
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- EyeBiotech Ltd.
- Industry
- Enrollment
- 960 participants
Conditions and interventions
Conditions
Interventions
- Aflibercept Drug
- Tiespectus Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 14, 2026
- Primary completion
- Jul 30, 2028
- Completion
- Jul 30, 2028
- Last update posted
- May 3, 2026
2026 – 2028
United States locations
- U.S. sites
- 9
- U.S. states
- 9
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Northern California Retina Vitreous Associates Medical Group, Inc. | Mountain View | California | 94040 | Recruiting |
| University Retina & Macula Associates, P.C. | Lemont | Illinois | 60439 | Recruiting |
| Mid Atlantic Retina Specialists | Hagerstown | Maryland | 21740 | Recruiting |
| Retina Consultants of Minnesota | Edina | Minnesota | 55435 | Recruiting |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | Recruiting |
| Erie Retina Research | Erie | Pennsylvania | 16505 | Recruiting |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | Recruiting |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | Recruiting |
| Pacific Northwest Retina | Bellevue | Washington | 98004 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07496567, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07496567 live on ClinicalTrials.gov.