AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Public ClinicalTrials.gov record NCT07509307. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Knee Osteoarthritis (AMAZE 6)
Study identification
- NCT ID
- NCT07509307
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 400 participants
Conditions and interventions
Conditions
Interventions
- NNC0487-0111 Drug
- Placebo (matched to NNC0487-0111) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 12, 2026
- Primary completion
- Jun 18, 2028
- Completion
- Jul 16, 2028
- Last update posted
- Apr 2, 2026
2026 – 2028
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neighborhood Healthcare | Escondido | California | 92025 | — |
| First Valley Medical Group | Lancaster | California | 93534 | — |
| Desert Oasis Healthcare | Palm Springs | California | 92262 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Westside Center For Clinical Research | Jacksonville | Florida | 32205 | — |
| CNS Healthcare | Jacksonville | Florida | 32256 | — |
| Advanced Res for Health Improve | Naples | Florida | 34102 | — |
| Clinical Investigation Spec Gurnee | Gurnee | Illinois | 60031 | — |
| Evanston Premier Hlthcr Res | Skokie | Illinois | 60077 | — |
| Monroe Biomedical Research, LLC | Louisville | Kentucky | 40213 | — |
| Arcturus Healthcare, PLC. | Troy | Michigan | 48098-6368 | — |
| Clinvest Research | Springfield | Missouri | 65807 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Hospital For Special Surgery | New York | New York | 10021 | — |
| Piedmont Healthcare/Research | Statesville | North Carolina | 28625 | — |
| Northwest Research Center | Portland | Oregon | 97202 | — |
| Mercy Family Clinic | Dallas | Texas | 75208 | — |
| Health Res of Hampton Roads | Newport News | Virginia | 23606 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 59 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07509307, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07509307 live on ClinicalTrials.gov.