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Recruiting Phase 2 Interventional

Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension

ClinicalTrials.gov ID: NCT07511361

Public ClinicalTrials.gov record NCT07511361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 9, 2026, 9:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Two-Part Study to Evaluate the Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who were recently hospitalized and concurrently experienced an episode of acute severe hypertension.

Study identification

NCT ID
NCT07511361
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Kardigan, Inc.
Industry
Enrollment
140 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 22, 2026
Primary completion
Nov 30, 2026
Completion
Jan 31, 2027
Last update posted
Sep 1, 2026

2026 – 2027

United States locations

U.S. sites
11
U.S. states
8
U.S. cities
11
Facility City State ZIP Site status
Western Nephrology and Metabolic Bone Disease, PC - Arvada Arvada Colorado 80002 Recruiting
Homestead Associates in Research Homestead Florida 33033 Recruiting
Progressive Medical Research Port Orange Florida 32127 Recruiting
Eagle Clinical Research Chicago Illinois 60621 Recruiting
Richmond University Medical Center (RUMC) Staten Island New York 10310 Recruiting
Research Innovations, LLC Beavercreek Ohio 05431 Recruiting
OnSite Clinical Solutions, LLC Fort Mill South Carolina 29715 Recruiting
Chattanooga Research & Medicine CHARM Chattanooga Tennessee 37404 Recruiting
Laguna Clinical Research Associates Laredo Texas 78041 Recruiting
Tapia Internal Medicine Clinic Paris Texas 75460 Recruiting
Baylor Scott and White Research Institute - Temple Temple Texas 76502 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07511361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 1, 2026 · Synced Sep 9, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07511361 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →