AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
Public ClinicalTrials.gov record NCT07533175. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Type 2 Diabetes (AMAZE 2)
Study identification
- NCT ID
- NCT07533175
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 630 participants
Conditions and interventions
Conditions
Interventions
- NNC0487-0111 Drug
- Placebo (matched to NNC0487-0111) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 12, 2026
- Primary completion
- May 14, 2028
- Completion
- Aug 6, 2028
- Last update posted
- Apr 26, 2026
2026 – 2028
United States locations
- U.S. sites
- 15
- U.S. states
- 9
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama Birmingham | Birmingham | Alabama | 35294 | Recruiting |
| Headlands Research California, LLC | Escondido | California | 92025 | Recruiting |
| Torrance Clinical Research Institute, Inc. | Lomita | California | 90717 | Recruiting |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | Recruiting |
| Northeast Research Institute | Fleming Island | Florida | 32003 | Recruiting |
| Jacksonville Ctr Clin Res | Jacksonville | Florida | 32216 | Recruiting |
| Florida Institute for Clinical Research, LLC | Orlando | Florida | 32825 | Recruiting |
| Oviedo Medical Research, LLC | Oviedo | Florida | 32765 | Recruiting |
| International Diabetes Center | Minneapolis | Minnesota | 55416 | Recruiting |
| Southgate Medical Group, LLP | West Seneca | New York | 14224 | Recruiting |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | Recruiting |
| M3 Wake Research Chattanooga | Chattanooga | Tennessee | 37421 | Recruiting |
| UT Southwestern Medical Center - Lingvay | Dallas | Texas | 75390 | Recruiting |
| PlanIt Research, PLLC | Houston | Texas | 77079 | Recruiting |
| National Clin Res Inc. | Richmond | Virginia | 23294 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 58 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07533175, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 26, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07533175 live on ClinicalTrials.gov.