SMART Trial Comparing Commonly Prescribed and Over the Counter Medications for the Treatment of Insomnia in Adults
Public ClinicalTrials.gov record NCT07542756. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Sequential Multiple Assignment Randomized Trial Comparing Commonly Prescribed and Over the Counter Medications for the Treatment of Insomnia in Adults
Study identification
- NCT ID
- NCT07542756
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- University of Pennsylvania
- Other
- Enrollment
- 1,200 participants
Conditions and interventions
Interventions
- Diphenhydramine, 25 mg Drug
- Diphenhydramine, 50 mg Drug
- Doxepin, 3 mg Drug
- Doxepin, 6 mg Drug
- Melatonin IR, 3 mg Dietary Supplement
- Melatonin IR, 5 mg Dietary Supplement
- Placebo Drug
- Sleep Hygiene Education Other
- Trazodone, 100 mg Drug
- Trazodone, 50 mg Drug
- Zolpidem, 10 mg Drug
- Zolpidem, 5 mg Drug
Drug · Dietary Supplement · Other
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2026
- Primary completion
- Dec 31, 2031
- Completion
- Dec 31, 2031
- Last update posted
- Apr 20, 2026
2026 – 2032
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07542756, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07542756 live on ClinicalTrials.gov.