A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

ClinicalTrials.gov ID: NCT07545772

Public ClinicalTrials.gov record NCT07545772. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 5, 2026, 4:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Brenipatide in the Treatment of Adult Participants With IBS-C

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated what side effects may occur, and the safety and efficacy in participants with Irritable Bowel Syndrome-Constipation (IBS-C). The study drug will be administered subcutaneously (SC) (under the skin) when compared with placebo. The study will last approximately 35 weeks.

Study identification

NCT ID: NCT07545772
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Eli Lilly and Company; Industry
Enrollment: 342 participants

Conditions and interventions

Conditions

Interventions

LY3537031 Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 28, 2026
Primary completion: Jun 30, 2027
Completion: Aug 31, 2027
Last update posted: Aug 23, 2026

2026 – 2027

United States locations

U.S. sites: 14
U.S. states: 10
U.S. cities: 14

Facility	City	State	ZIP	Site status
Del Sol Research Management - Mesa	Mesa	Arizona	85206	Recruiting
Smart Cures Clinical Research	Anaheim	California	92806	Recruiting
Om Research LLC	Lancaster	California	93534	Recruiting
United Medical Doctors - Los Alamitos	Los Alamitos	California	90720	Recruiting
Encore Medical Research	Hollywood	Florida	33024	Recruiting
Springfield Clinic - First	Springfield	Illinois	62702	Recruiting
Gastroenterology Health Partners	New Albany	Indiana	47150	Recruiting
Gastroenterology Health Partners	Louisville	Kentucky	40218	Recruiting
New York Gastroenterology Associates	New York	New York	10075	Recruiting
Ohio Gastroenterology	Columbus	Ohio	43202	Recruiting
University Gastroenterology	Providence	Rhode Island	02905	Recruiting
Biopharma Informatic, LLC	McAllen	Texas	78503	Recruiting
Southern Star Research Institute	San Antonio	Texas	78229	Recruiting
GI Alliance-Webster	Webster	Texas	77598	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07545772, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Aug 23, 2026 · Synced Sep 5, 2026

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The complete protocol, eligibility criteria, and contact information for NCT07545772 live on ClinicalTrials.gov.

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