ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Public ClinicalTrials.gov record NCT07553637. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Trial of ALTO-207 in Adults With Treatment-resistant Depression
Study identification
- NCT ID
- NCT07553637
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Alto Neuroscience
- Industry
- Enrollment
- 178 participants
Conditions and interventions
Conditions
Interventions
- ALTO-207 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2026
- Primary completion
- Oct 31, 2027
- Completion
- Nov 30, 2027
- Last update posted
- Apr 27, 2026
2026 – 2027
United States locations
- U.S. sites
- 38
- U.S. states
- 17
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site 7074 | Birmingham | Alabama | 35294 | Not yet recruiting |
| Site 7173 | Dothan | Alabama | 36345 | Not yet recruiting |
| Site 7000 | Phoenix | Arizona | 85012 | Recruiting |
| Site 7153 | Chino | California | 91710 | Not yet recruiting |
| Site 7156 | Oakland | California | 94610 | Not yet recruiting |
| Site 7082 | Oceanside | California | 92056 | Recruiting |
| Site 7159 | Palo Alto | California | 94304 | Not yet recruiting |
| Site 7016 | Sacramento | California | 95655 | Not yet recruiting |
| Site 7144 | San Diego | California | 92123 | Recruiting |
| Site 7171 | Valley Village | California | 91607 | Not yet recruiting |
| Site 7152 | Saint Augustine | Florida | 32086 | Recruiting |
| Site 7148 | Albany | Georgia | 31707 | Recruiting |
| Site 7146 | Atlanta | Georgia | 30060 | Not yet recruiting |
| Site 7064 | Peachtree Corners | Georgia | 30078 | Not yet recruiting |
| Site 7141 | Savannah | Georgia | 31406 | Recruiting |
| Site 7169 | Indianapolis | Indiana | 46202 | Not yet recruiting |
| Site 7151 | Annapolis | Maryland | 21401 | Recruiting |
| Site 7054 | Pikesville | Maryland | 21208 | Not yet recruiting |
| Site 7166 | Worcester | Massachusetts | 01606 | Not yet recruiting |
| Site 7155 | Ann Arbor | Michigan | 48109 | Not yet recruiting |
| Site 7154 | Bloomfield Hills | Michigan | 48302 | Recruiting |
| Site 7170 | Amherst | New York | 14226 | Not yet recruiting |
| Site 7055 | Cedarhurst | New York | 11516 | Not yet recruiting |
| Site 7162 | Lewiston | New York | 14214 | Not yet recruiting |
| Site 7157 | Syracuse | New York | 13210 | Not yet recruiting |
| Site 7143 | Charlotte | North Carolina | 28287 | Recruiting |
| Site 7029 | Cincinnati | Ohio | 45215 | Recruiting |
| Site 7158 | Garfield Heights | Ohio | 44125 | Not yet recruiting |
| Site 7172 | East Providence | Rhode Island | 02914 | Not yet recruiting |
| Site 7176 | Dallas | Texas | 75243 | Not yet recruiting |
| Site 7160 | Fort Worth | Texas | 76104 | Not yet recruiting |
| Site 7150 | Galveston | Texas | 77555 | Not yet recruiting |
| Site 7175 | Houston | Texas | 77007 | Not yet recruiting |
| Site 7145 | Houston | Texas | 77030 | Recruiting |
| Site 7161 | Irving | Texas | 75062 | Recruiting |
| Site 7177 | Fairfax | Virginia | 22030 | Not yet recruiting |
| Site 7128 | Seattle | Washington | 98004 | Not yet recruiting |
| Site 7163 | South Charleston | West Virginia | 25303 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07553637, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07553637 live on ClinicalTrials.gov.