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Recruiting Phase 3 Interventional Accepts healthy volunteers

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

ClinicalTrials.gov ID: NCT07567040

Public ClinicalTrials.gov record NCT07567040. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 4:53 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly placebo drops in both eyes. The primary outcome is the two-year cumulative incidence of nearsightedness. The second aim of this project will determine whether atropine is associated with slower eye growth in children receiving nightly drops of atropine versus placebo.

Study identification

NCT ID
NCT07567040
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Ohio State University
Other
Enrollment
664 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
6 Years to 11 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 26, 2026
Primary completion
May 14, 2028
Completion
May 14, 2028
Last update posted
Aug 20, 2026

2026 – 2028

United States locations

U.S. sites
13
U.S. states
10
U.S. cities
13
Facility City State ZIP Site status
University of Alabama School of Optometry Birmingham Alabama 35233 Recruiting
University of California, Berkeley, School of Optometry Berkeley California 94720 Recruiting
Southern California College of Optometry at Marshall B. Ketchum University Fullerton California 92831 Recruiting
Stanford University Palo Alto California 94303 Not yet recruiting
Illinois College of Optometry Chicago Illinois 60616 Recruiting
Indiana University Bloomington Indiana 47405 Recruiting
New England College of Optometry Boston Massachusetts 02115 Recruiting
State University of New York College of Optometry New York New York 10036 Recruiting
Case Western Reserve Department of Ophthalmology Cleveland Ohio 44106 Not yet recruiting
The Ohio State University College of Optometry Columbus Ohio 43210 Recruiting
Pennsylvania College of Optometry at Drexel University Elkins Park Pennsylvania 19027 Not yet recruiting
Southern College of Optometry Memphis Tennessee 38104 Recruiting
University of Houston College of Optometry Houston Texas 77004 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07567040, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 20, 2026 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07567040 live on ClinicalTrials.gov.

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