AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Public ClinicalTrials.gov record NCT07571109. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Obstructive Sleep Apnoea Treated With Positive Airway Pressure (AMAZE 4)
Study identification
- NCT ID
- NCT07571109
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Interventions
- NNC0487-0111 Drug
- Placebo (matched to NNC0487-0111) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 4, 2026
- Primary completion
- Jun 25, 2028
- Completion
- Jul 23, 2028
- Last update posted
- May 5, 2026
2026 – 2028
United States locations
- U.S. sites
- 20
- U.S. states
- 11
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Dignity Health, Mercy Gilbert | Gilbert | Arizona | 85297 | — |
| DM Clinical | Bradenton | Florida | 34209 | — |
| Essence MD Research | Naples | Florida | 34102 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| NeuroTrials Research, Inc. | Atlanta | Georgia | 30328 | — |
| Physicians Research Associates | Lawrenceville | Georgia | 30046 | — |
| Chicago Research Center, Inc | Chicago | Illinois | 60634 | — |
| Weil Cornell Medicine | New York | New York | 10021 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Clinical Research Associates of Central PA, LLC | DuBois | Pennsylvania | 15801 | — |
| Bogan Sleep Consultants, LLC | Columbia | South Carolina | 29201 | — |
| Epic Medical Research | DeSoto | Texas | 75115 | — |
| Advanced Neurology Epilepsy and Sleep Center ANESC | El Paso | Texas | 79912 | — |
| Biorhythms Center for Integrative Sleep Medicine | El Paso | Texas | 79912 | — |
| Houston Pulmonary Medicine Associates, PA | Houston | Texas | 77089 | — |
| Sleep Therapy Research Center | San Antonio | Texas | 78229 | — |
| Tricoastal Sleep Center | Sugar Land | Texas | 77478 | — |
| Rainier Clin Res Ctr Inc | Renton | Washington | 98057 | — |
| Seattle Clinical Research Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 70 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07571109, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07571109 live on ClinicalTrials.gov.