A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Public ClinicalTrials.gov record NCT07589595. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Placebo-Controlled Clinical Trial to Assess the Safety and Efficacy of Donanemab in Participants With Early Cognitive Decline, at Least One Core Clinical Feature of Dementia With Lewy Bodies, and Confirmation of Alpha-Synuclein and Amyloid Co-pathology
Study identification
- NCT ID
- NCT07589595
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 350 participants
Conditions and interventions
Interventions
- Donanemab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 55 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2026
- Primary completion
- Jul 31, 2028
- Completion
- Jul 31, 2028
- Last update posted
- May 14, 2026
2026 – 2028
United States locations
- U.S. sites
- 42
- U.S. states
- 17
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| TrialSphere Corp | Chandler | Arizona | 85286 | — |
| HonorHealth Research Institute | Scottsdale | Arizona | 85258 | — |
| Profound Research LLC | Carlsbad | California | 92011 | — |
| Irvine Clinical Research | Irvine | California | 92614 | — |
| UCSD - Altman Clinical and Translational Research Institute (ACTRI) | La Jolla | California | 92037 | — |
| Stanford Neuroscience Health Center | Palo Alto | California | 94304 | — |
| CenExel Rocky Mountain Clinical Research | Englewood | Colorado | 80113 | — |
| Ki Health Partners, LLc, dba New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| VIN - Aventura | Aventura | Florida | 33180 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Norman Fixel Institute for Neurological Diseases (FIND) | Gainesville | Florida | 32608 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | — |
| K2 Medical Research ORLANDO | Maitland | Florida | 32751 | — |
| BRP-Kendal Lakes | Miami | Florida | 33175 | — |
| Renstar Medical Research | Ocala | Florida | 34471 | — |
| Charter Research - Orlando | Orlando | Florida | 32803 | — |
| Axiom Brain Health LLC | Tampa | Florida | 33609 | — |
| Palm Beach Neurology | West Palm Beach | Florida | 33407 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Indiana University Health Neuroscience Center | Indianapolis | Indiana | 46202 | — |
| The University of Kansas - Clinical Research Center | Fairway | Kansas | 66205 | — |
| Massachusetts General Hospital - Charlestown | Charlestown | Massachusetts | 02129 | — |
| Neurology Center of New England | Foxborough | Massachusetts | 02035 | — |
| Headlands Eastern MA LLC | Plymouth | Massachusetts | 02360 | — |
| QUEST Research Institute | Farmington Hills | Michigan | 48334 | — |
| Struthers Parkinson's Center | Golden Valley | Minnesota | 55427 | — |
| Mayo Clinic in Rochester, Minnesota | Rochester | Minnesota | 55905 | — |
| Citizens Memorial Hospital District | Bolivar | Missouri | 65613 | — |
| Summit Headlands | Portland | Oregon | 97210 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| K2 Medical Research - East Providence | East Providence | Rhode Island | 02914 | — |
| Gadolin Research | Beaumont | Texas | 77702 | — |
| Kerwin Medical Center | Dallas | Texas | 75231 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77054 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| The University of Texas Health Science Center | San Antonio | Texas | 78229 | — |
| Re:Cognition Health | Fairfax | Virginia | 22031 | — |
| EvergreenHealth | Kirkland | Washington | 98034 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07589595, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 14, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07589595 live on ClinicalTrials.gov.