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ClinicalTrials.gov public records Last synced May 22, 2026, 1:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 78 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Acute Appendicitis Clear all
Completed Not applicable Interventional
View directory record Official record
Conditions
Appendiceal Abscess
Interventions
Operation on Admission, Drainage and Interval Appendectomy
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 2, 2009 · Synced May 22, 2026, 1:35 AM EDT
Not yet recruiting Phase 4 Interventional
View directory record Official record
Conditions
Acute, Perforated Appendicitis
Interventions
Irrigation with PVI, Usual care
Drug · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
2 Years to 17 Years
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced May 22, 2026, 1:35 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
Appendectomy, Observation
Procedure · Other
Lead sponsor
Marshall University
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced May 22, 2026, 1:35 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Complicated Intra-abdominal Infections, Complicated Appendicitis
Interventions
Eravacycline, Meropenem, Placebo
Drug
Lead sponsor
Tetraphase Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
6
States / cities
Los Angeles, California • Indianapolis, Indiana • Las Vegas, Nevada + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced May 22, 2026, 1:35 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Pain, Appendicitis, Bias, Racial, Fractures, Bone
Interventions
Department-level audit and feedback and electronic health record-embedded clinical decision support
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
0 Years and older
Enrollment
22,032 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced May 22, 2026, 1:35 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Appendicitis
Interventions
DS-Ligature Clip
Device
Lead sponsor
Aesculap AG
Industry
Eligibility
16 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Marina del Rey, California • Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2015 · Synced May 22, 2026, 1:35 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Appendicitis
Interventions
Operative management, Drainage or antibiotics
Procedure · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Appendicitis
Interventions
Open appendectomy using Alexis Wound Retractor followed by standardized wound closure, Open appendectomy with standardized wound closure
Device · Procedure
Lead sponsor
Santa Barbara Cottage Hospital
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Nov 22, 2018 · Synced May 22, 2026, 1:35 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Appendicitis
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
3 Years to 18 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced May 22, 2026, 1:35 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Appendicitis
Interventions
Piperacillin/Tazobactam, Surgical Treatment
Drug · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
6 Years to 17 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Appendicitis
Interventions
Restricted Duration of SOC Antibiotic Use, Liberal Duration of SOC Antibiotic Use
Other
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
657 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Appendicitis
Interventions
Appy CDS
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
5 Years to 20 Years
Enrollment
5,940 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Oakland, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
5 days of IV antibiotics (ceftriaxone and metronidazole), Home with oral antibiotics when eating (ampicillin/clavulanic acid)
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 18 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Appendicitis
Interventions
Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin, Appendectomy
Drug · Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,552 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
25
States / cities
Sylmar, California • Torrance, California • Aurora, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Suppurative Appendicitis
Interventions
Patients discharged home the same day following appendectomy
Other
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Appendicitis
Interventions
transvaginal appendectomy
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced May 22, 2026, 1:35 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Appendicitis, Perforated Appendicitis, Ruptured Appendicitis, Complicated Appendicitis
Interventions
Early Appendectomy, Interval Appendectomy, Antibiotics
Procedure · Drug
Lead sponsor
University of Michigan
Other
Eligibility
5 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced May 22, 2026, 1:35 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Acute Appendicitis
Interventions
Sulfur hexafluoride lipid-type A microspheres
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
8 Years to 17 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced May 22, 2026, 1:35 AM EDT
Withdrawn Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Appendicitis, Pain, Postoperative
Interventions
Non-narcotic pain control
Drug
Lead sponsor
University of Utah
Other
Eligibility
Up to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced May 22, 2026, 1:35 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
Motion sickness wristband, Chewing Gum
Device · Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
6 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced May 22, 2026, 1:35 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
Ampicillin, gentamicin, clindamycin, flagyl, ceftazidime
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Month to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 5, 2007 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Perforated Appendicitis
Interventions
Irrigation, No Irrigation
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Month to 17 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 31, 2012 · Synced May 22, 2026, 1:35 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Appendicitis
Interventions
Polymetric clips, Endoscopic Staplers
Device · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced May 22, 2026, 1:35 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Appendicitis, Children
Interventions
Patient Activation Tool
Other
Lead sponsor
Peter Minneci
Other
Eligibility
7 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced May 22, 2026, 1:35 AM EDT