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ClinicalTrials.gov public records Last synced May 21, 2026, 8:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Aggressive Childhood Behavior Clear all
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Methylphenidate HCl, Risperidone, Parent Management Training (PMT), Placebo
Drug · Behavioral
Lead sponsor
Michael Aman
Other
Eligibility
6 Years to 12 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
4
States / cities
Stony Brook, New York • Cleveland, Ohio • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aggressive Childhood Behavior
Interventions
Mental Health Enhanced Positive Behavioral Interventions and Supports (PBIS-MH), Racial/Ethnic Discrimination Interventions (RED)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
10 Years to 105 Years
Enrollment
4,840 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced May 21, 2026, 8:46 PM EDT
Recruiting Phase 2 Interventional
View directory record Official record
Conditions
Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders, Self-injury
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Jeremy Veenstra-vanderweele
Other
Eligibility
12 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Staten Island, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced May 21, 2026, 8:46 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Neuroblastoma, Ovarian Cancer, Testicular Germ Cell Tumor
Interventions
alemtuzumab, methylprednisolone, prednisone, flow cytometry, immunologic technique, pharmacological study
Biological · Drug · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
Not listed
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 13, 2010 · Synced May 21, 2026, 8:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Problem Behavior, Aggression, Self Injury
Interventions
Extinction-only condition, Rate-drop condition, Rate-hold condition, Magnitude-drop condition, Magnitude-hold condition, Quality-drop condition, Quality-hold condition, Rate-drop/quality-increase condition
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
3 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 21, 2026, 8:46 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Autism, Asperger's Disorder, Pervasive Developmental Disorder
Interventions
Aripiprazole
Drug
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
6 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Medford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder (ASD, Asperger's Disorder, Pervasive Developmental Disorder (PDD-NOS)
Interventions
Cognitive-Behavioral Therapy (CBT) for Irritability
Behavioral
Lead sponsor
Yale University
Other
Eligibility
9 Years to 16 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Disruptive Behavior, Aggression, Anger, Irritability, Noncompliance
Interventions
Cognitive-Behavioral Therapy for Anger and Aggression, Supportive Psychotherapy (SPT)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
8 Years to 16 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aggression
Interventions
CBI, NUT
Behavioral · Dietary Supplement
Lead sponsor
University of Pennsylvania
Other
Eligibility
11 Years to 12 Years
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Childhood Aggression
Interventions
DBT for children, Enhanced Supportive-Educational therapy
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
6 Years to 12 Years · Male only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Brewster, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2018 · Synced May 21, 2026, 8:46 PM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Behavior, Child
Interventions
CP+/No REACT, CP+ and REACT
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
10 Years to 14 Years
Enrollment
1,093 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama • Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced May 21, 2026, 8:46 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Autism
Interventions
Divalproex sodium, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
5 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 27, 2024 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Problem Behavior, Aggression
Interventions
Response Blocking
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
6 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced May 21, 2026, 8:46 PM EDT
Recruiting Phase 4 Interventional
View directory record Official record
Conditions
ADHD - Attention Deficit Disorder With Hyperactivity, Irritability, Aggression Childhood
Interventions
CNS Stimulant, Placebo, CNS Stimulant open label first phase
Drug · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
7 Years to 12 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Autism
Interventions
Oxcarbazepine, Placebo/sugar pill
Drug · Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
5 Years to 17 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced May 21, 2026, 8:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Problem Behavior, Aggression, Self-Injury
Interventions
CDT, Control
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced May 21, 2026, 8:46 PM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Intermittent Explosive Disorder, Childhood Aggression, Oppositional Defiant Disorder, Attention Deficit Disorder
Interventions
Parent Management Training, Placebo, Intuniv
Behavioral · Other · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
6 Years to 12 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 12, 2018 · Synced May 21, 2026, 8:46 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger, Aggression, Asperger Syndrome, Pervasive Developmental Disorder
Interventions
Behavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years to 19 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced May 21, 2026, 8:46 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Disruptive Behavior, Aggression Childhood, Anger, Non-Compliance, Patient, Irritable Mood
Interventions
Parent Management Training
Behavioral
Lead sponsor
Yale University
Other
Eligibility
3 Years to 9 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced May 21, 2026, 8:46 PM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Autism, Intellectual Disability
Interventions
Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
8 Years to 16 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced May 21, 2026, 8:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Problem Behavior, Aggression, Self-Injury
Interventions
Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking, Research Units in Behavioral Intervention (RUBI) protocol
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced May 21, 2026, 8:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aggression Childhood, Bullying Victimization, Social Behavior
Interventions
Universal, classroom-based, Bullying and Aggression Prevention Program
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years and older
Enrollment
1,008 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced May 21, 2026, 8:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders, Passive-Aggressive Personality Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1988 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced May 21, 2026, 8:46 PM EDT