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Conditions: Airway Complication of Anesthesia
Interventions: Advanced airway management; Procedure
Lead sponsor: University of Turin, Italy; Other
Eligibility: 18 Years and older
Enrollment: 10,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Dallas, Texas • Houston, Texas

Conditions: Airway Management, Infant ALL, Children, Only, Endotracheal Intubation
Interventions: Airway positioning per specified protocol followed by Direct Laryngoscopy and Endotracheal Intubation, Airway positioning per provider preference followed by Direct Laryngoscopy and Endotracheal Intubation; Procedure
Lead sponsor: Tufts Medical Center; Other
Eligibility: 1 Month to 48 Months
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Airway Management
Interventions: Low-flow nasal supplemental oxygen with a conventional nasal cannula during tracheal intubation with the C-MAC video laryngoscope, High-flow nasal supplemental oxygen (Fisher & Paykel, Auckland, New Zealand) during tracheal intubation with the C-MAC video laryngoscope; Device
Lead sponsor: Thomas Riva; Other
Eligibility: Up to 52 Weeks
Enrollment: 1,192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Asthma, Obesity
Interventions: L-ctirulline, Matching Placebo; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Adverse Effect of Unspecified General Anesthetics
Interventions: Supreme Laryngeal mask airway, Proseal laryngeal mask airway; Device
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Airway Management, Tracheal Intubation, Critical Illness, Training
Interventions: Delphi procedure; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: Not listed
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Asthma
Interventions: NIPPV (PALMtop PTV), Volumetric CO2 (NM3), USCOM; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 2 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Obstructive Sleep Apnea (OSA)
Interventions: Weekly phone calls, Frequently asked questions, Usual care; Behavioral
Lead sponsor: CAMC Health System; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Charleston, West Virginia

Conditions: Tracheal Intubation
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 1,288 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 16
States / cities: Scottsdale, Arizona • Los Angeles, California • Modesto, California + 13 more

Conditions: Asthma
Interventions: PF-07275315, Placebo; Drug · Other
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 252 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 36
States / cities: Mobile, Alabama • Chandler, Arizona • Lancaster, California + 29 more

Conditions: COPD, Chronic Bronchitis, Emphysema
Interventions: pneumatic vest, placebo pneumatic vest; Device · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 45 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Nasal Alar Collapse, Bilateral
Interventions: Polyester Implants; Device
Lead sponsor: Medtronic Xomed, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 5
States / cities: Sacramento, California • Atlanta, Georgia • Downers Grove, Illinois + 2 more

Conditions: Asthma, Airway Inflammation, Airflow Obstruction, Airway Hyperactivity
Interventions: Pioglitazone Hydrochloride; Drug
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 2
States / cities: Bethesda, Maryland • Falls Church, Virginia

Conditions: Obstructive Sleep Apnea (OSA)
Interventions: Pillar Palatal Implant System, Sham system; Device
Lead sponsor: Medtronic Xomed, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 7
States / cities: Little Rock, Arkansas • Berkeley, California • Denver, Colorado + 4 more

Conditions: Preterm Neonates
Interventions: Gradual weaning from Nasal CPAP in preterm neonates; Procedure
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 24 Weeks to 32 Weeks
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Acute Respiratory Distress
Interventions: CMAC videolaryngoscope, Direct Laryngoscopy; Procedure
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 198 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Obstructive Sleep Apnea, Type 2 Diabetes
Interventions: active CPAP Therapy, sham CPAP therapy; Device
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Heart Arrest, Out-Of-Hospital, Wounds and Injuries, Respiratory Insufficiency in Children, Child, Only, Critical Illness
Interventions: BVM, SGA, ETI; Device
Lead sponsor: Ohio State University; Other
Eligibility: 24 Hours to 17 Years
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 10
States / cities: Tucson, Arizona • Los Angeles, California • Sacramento, California + 7 more

Conditions: Acute Respiratory Failure
Interventions: Hyperangulated video laryngoscope blade, Standard geometry video laryngoscope blade; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 18
States / cities: Los Angeles, California • Stanford, California • Denver, Colorado + 14 more

Conditions: Healthy Control
Interventions: ozone; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 40 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2017
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Mask Ventilation, Airway Obstruction Upper, Airway Management
Interventions: Articulated Oral Airway, Guedel oral airway (active comparator); Device
Lead sponsor: Ron Abrons; Other
Eligibility: 18 Years to 99 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Acute Respiratory Failure
Interventions: Bougie, Endotracheal tube; Device
Lead sponsor: Hennepin Healthcare Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 757 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: General Anesthesia With Endotracheal Intubation in Surgery
Interventions: Mask then nasopharyngeal, Nasopharyngeal then mask; Other
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Dupilumab, Placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 40 Years to 85 Years
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 10
States / cities: Birmingham, Alabama • Miami, Florida • Cordele, Georgia + 7 more

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International obServational sTudy on AiRway manaGement in operAting Room and Non-operaTing Room anaEsthesia

Defining the 'Sniffing Position" in Infants and Toddlers - A Pilot Study

Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)

Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes

Comparison of ProSeal Laryngeal Mask Airway to Laryngeal Mask Airway Supreme

Curriculum for Airway Skills in Critically Ill Adults: a Delphi Evaluation

Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations

Weekly Phone Calls Versus Brief Patient Education to Improve Continuous Positive Airway Pressure (CPAP) Compliance

Endotracheal Intubation Among the Critically Ill: HEMAIR Pilot Study

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation

Study of Polyester Implants for the Treatment of External Nasal Valve Collapse (NVC)

Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma

Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea

Trial of Weaning of Nasal Continuous Positive Airway Pressure (CPAP)

Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management

Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes

Pediatric Prehospital Airway Resuscitation Trial

Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial

Genetic Susceptibility TO Ozone-induced Airway Inflammation in Humans

The Articulated Oral Airway as an Aid to Mask Ventilation

Bougie Use in Emergency Airway Management

Cohort 2 Efficacy of Nasopharyngeal Ventilation With Endotracheal Tube for Surgery

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.