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Showing 1–24 of 81 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Amblyopia Clear all
Completed Not applicable Interventional

A Patch Free Treatment for Young Children With Amblyopia

NCT04086524
View directory record Official record
Conditions
Amblyopia, Binocular Vision Disorder
Interventions
Binocular cartoon treatment at home, Patching, Binocular cartoon treatment in office
Other
Lead sponsor
University of Waterloo
Other
Eligibility
36 Months to 83 Months
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Not applicable Interventional

CURESIGHT BINOCULAR AMBLYOPIA TREATMENT STUDY

NCT04785690
View directory record Official record
Conditions
Amblyopia
Interventions
CureSight, Patching
Device
Lead sponsor
NovaSight
Industry
Eligibility
4 Years to 8 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 4, 2026, 8:45 PM EDT
Terminated Phase 1 Interventional

Proof of Concept Study of Binocular Videogames Versus Patching for Amblyopia

NCT04784390
View directory record Official record
Conditions
Amblyopia
Interventions
Binocular video games, Patching of the sound eye
Device
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
4 Years to 12 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Gainesville, Florida • Maitland, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Phase 3 Interventional Results available

Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children

NCT00525174
View directory record Official record
Conditions
Amblyopia
Interventions
Bangerter filters, Patching, Near activities
Device · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 9 Years
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Phase 3 Interventional Results available

Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Years Old

NCT00315302
View directory record Official record
Conditions
Amblyopia
Interventions
Atropine, Plano Lens
Drug · Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 6 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Fullerton, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2016 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Not applicable Interventional Results available

Study of Binocular Computer Activities for Treatment of Amblyopia

NCT02200211
View directory record Official record
Conditions
Amblyopia
Interventions
iPad®, Patching 2 hours per day, 7 days per week
Device · Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
5 Years to 16 Years
Enrollment
485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Rochester, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Phase 3 Interventional

Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia

NCT00094744
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2010 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Not applicable Interventional Results available

Luminopia One Amblyopia Vision Improvement Study

NCT03608150
View directory record Official record
Conditions
Amblyopia
Interventions
Luminopia One, Refractive Correction
Device
Lead sponsor
Luminopia
Industry
Eligibility
4 Years to 7 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
22
States / cities
Los Angeles, California • Gainesville, Florida • Maitland, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Binocular Treatment of Amblyopia Before and After Strabismus Surgery

NCT01791946
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Binocular Treatment, Sham Binocular Treatment
Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 60 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Sep 4, 2026, 8:45 PM EDT
Recruiting Phase 3 Interventional

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

NCT06380517
View directory record Official record
Conditions
Amblyopia
Interventions
Luminopia, Eye Patch
Device · Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
4 Years to 7 Years
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
72
States / cities
Birmingham, Alabama • Glendale, Arizona • Scottsdale, Arizona + 58 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Treatment of Residual Amblyopia With Donepezil

NCT01584076
View directory record Official record
Conditions
Amblyopia
Interventions
Donepezil, Patching
Drug · Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
3
States / cities
Boston, Massachusetts • Waltham, Massachusetts • Weymouth, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 4, 2026, 8:45 PM EDT
Recruiting Phase 3 Interventional

Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

NCT06524882
View directory record Official record
Conditions
Amblyopia
Interventions
Vivid Vision, Luminopia, Optical Correction
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
8 Years to 12 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
58
States / cities
Birmingham, Alabama • Glendale, Arizona • Scottsdale, Arizona + 46 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 4, 2026, 8:45 PM EDT
Completed No phase listed Observational Results available

Observational Study of Optical Correction for Strabismic Amblyopia in Children 3 to <7 Years Old

NCT00669539
View directory record Official record
Conditions
Amblyopia
Interventions
Not listed
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 6 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Evaluation and Treatment of Pediatric Eye Diseases

NCT00006422
View directory record Official record
Conditions
Ocular Motility Disorder
Interventions
current standard of care treatments
Procedure
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 4, 2026, 8:45 PM EDT
Terminated No phase listed Observational

Bilateral and Unilateral Amblyopia Treatment Study

NCT03780205
View directory record Official record
Conditions
Amblyopia
Interventions
Prescription glasses for bilateral amblyopia, Prescription glasses for unilateral amblyopia
Other
Lead sponsor
Salus University
Other
Eligibility
3 Years to 10 Years
Enrollment
1 participant
Timeline
2019 – 2020
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2020 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Multimodal Physician Intervention to Detect Amblyopia

NCT01109459
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Pediatric blood pressure screening, Pediatric vision screening
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Not listed
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 22, 2010 · Synced Sep 4, 2026, 8:45 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Vision In Preschoolers Study (VIP Study)

NCT00038753
View directory record Official record
Conditions
Amblyopia, Strabismus, Refractive Error
Interventions
Vision Screening
Procedure
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
36 Months to 59 Months
Healthy volunteers
Accepts healthy volunteers
U.S. locations
5
States / cities
Berkeley, California • Boston, Massachusetts • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2009 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia

NCT03109314
View directory record Official record
Conditions
Amblyopia
Interventions
Donepezil, Single-letter training, Uncrowd training
Drug · Behavioral
Lead sponsor
Dennis Levi
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Phase 3 Interventional Results available

Increasing Patching for Amblyopia in Children 3 to < 8 Years Old

NCT00945100
View directory record Official record
Conditions
Amblyopia
Interventions
Eye Patch
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Fullerton, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Sep 4, 2026, 8:45 PM EDT
Completed Not applicable Interventional Results available

Binocular Dig Rush Game Treatment for Amblyopia

NCT02983552
View directory record Official record
Conditions
Amblyopia
Interventions
iPad®, Spectacle correction
Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
4 Years to 12 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
61
States / cities
Birmingham, Alabama • Glendale, Arizona • Anaheim, California + 49 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 4, 2026, 8:45 PM EDT
Completed No phase listed Interventional Results available

A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming

NCT03066063
View directory record Official record
Conditions
Amblyopia, Ocular Motility Disorders
Interventions
iCare, Amblyopia standard of Care, CI standard of Care
Device · Behavioral
Lead sponsor
Barron Associates, Inc.
Industry
Eligibility
4 Years to 18 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 4, 2026, 8:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Amblyopia Treatment for Children Aged 8 to 12 Years

NCT07281742
View directory record Official record
Conditions
Amblyopia
Interventions
Curesight dichoptic videos
Device
Lead sponsor
Retina Foundation of the Southwest
Other
Eligibility
8 Years to 12 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 4, 2026, 8:45 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Light-deprivation Utilized to Mitigate Amblyopia

NCT02685423
View directory record Official record
Conditions
Amblyopia
Interventions
Binocular deprivation 10 days, Vision training
Behavioral
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Sep 4, 2026, 8:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska

NCT04068129
View directory record Official record
Conditions
Amblyopia, Anisometropia
Interventions
photoscreen
Device
Lead sponsor
Alaska Blind Child Discovery
Other
Eligibility
6 Months to 40 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 4, 2026, 8:45 PM EDT