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Terminated Phase 3 Interventional Results available

Trial Comparing Patching With Active Vision Therapy to Patching With Control Vision Therapy as Treatment for Amblyopia

ClinicalTrials.gov ID: NCT00587171

Public ClinicalTrials.gov record NCT00587171. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 8:30 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Trial Comparing Patching With Active Vision Therapy to Patching With Control Vision Therapy as Treatment for Amblyopia in Children 7 to <13 Years Old

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is comparing the effectiveness of patching combined with active vision therapy plus near activities versus patching combined with control vision therapy plus near activities for moderate amblyopia (20/40-20/100) in 7 to \<13 year olds. The primary outcome measure is the proportion of patients with visual acuity of 20/25 or better in the amblyopic eye at the 17-week masked exam. These patients will be considered treatment responders. The primary analysis will consist of a comparison between the 2 treatment groups of the proportion of treatment responders with adjustment for baseline visual acuity. Secondary outcomes are stereoacuity at the 17-week masked exam, mean improvement in visual acuity at the 17-week masked exam, and rate of improvement of visual acuity.

Study identification

NCT ID
NCT00587171
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Enrollment
19 participants

Conditions and interventions

Conditions

Interventions

Device · Procedure

Eligibility (public fields only)

Age range
7 Years to 12 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2008
Primary completion
Feb 28, 2009
Completion
Sep 30, 2009
Last update posted
Jul 12, 2016

2008 – 2009

United States locations

U.S. sites
7
U.S. states
6
U.S. cities
7
Facility City State ZIP Site status
UAB Pediatric Eye Care; Birmingham Health Care Birmingham Alabama 35294
Bascom Palmer Eye Institute Miami Florida 33136
Indiana University School of Optometry Bloomington Indiana 47405
Casey Eye Institute Portland Oregon 97239
Pediatric Ophthalmology of Erie Erie Pennsylvania 16501
Family Eye Group Lancaster Pennsylvania 17601
Southern College of Optometry Memphis Tennessee 38104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00587171, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 12, 2016 · Synced Sep 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00587171 live on ClinicalTrials.gov.

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