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ClinicalTrials.gov public records Last synced May 22, 2026, 1:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Conditions
Diabetes Mellitus, Critical Limb Ischemia, Lower Limb Amputation Knee, Peripheral Arterial Disease
Interventions
Active Arm N-acetyl cysteine (NAC), Placebo Arm
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
30 Years to 90 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Appendicitis
Interventions
DS-Ligature Clip
Device
Lead sponsor
Aesculap AG
Industry
Eligibility
16 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Marina del Rey, California • Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2015 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation Stump
Interventions
Prosthetic socket for transtibial amputee
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 29, 2022 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
Conditions
Other and Unspecified Complications of Amputation Stump
Interventions
Otto Bock C-Leg, Otto Bock Genium
Device
Lead sponsor
Jason Highsmith
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional
Conditions
Multiple Sclerosis, Spinal Cord Injury, Chronic Pain, Other and Unspecified Amputation Stump Complications, Muscular Dystrophies, Low Back Pain
Interventions
Pain Self-Management Intervention #1, Pain Self-Management Intervention #2, Pain Self-Management Intervention #3, Pain Self-Management Intervention #4
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation, Chronic Pain
Interventions
morphine and mexiletine
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2003
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2006 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
Conditions
Amputation Stumps, Amputees, Amputation, Lower Limb Deformities, Congenital, Prosthesis User, Prosthesis
Interventions
Moisture Management Liner, Control Liner
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Holliston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced May 22, 2026, 1:34 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
Conditions
Amputation Stumps, Neuroma
Interventions
Bupivacaine, Placebo
Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2015 · Synced May 22, 2026, 1:34 AM EDT
Terminated Not applicable Interventional Results available
Conditions
Amputation Stump, Amputation, Amputees, Lower Limb Deformity, Prosthesis User, Prosthesis
Interventions
Moisture Management Liner
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Holliston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation, Phantom Limb Pain, Stump Pain
Interventions
perineural ropivicaine
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2018 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation
Interventions
adaptive prosthetic socket
Device
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
New York, New York • Milwaukee, New York, Nicosia, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 31, 2012 · Synced May 22, 2026, 1:34 AM EDT
Active, not recruiting Not applicable Interventional Results available
Conditions
Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain, Stump Pain
Interventions
Altius
Device
Lead sponsor
Neuros Medical, Inc.
Industry
Eligibility
21 Years and older
Enrollment
607 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
22
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Denver, Colorado + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Pancreatic Fistula, Distal Pancreatectomy Complications, Falciform Patch Pancreatic Closure, Fibrin Glue Pancreatic Closure
Interventions
Falciform patch and fibrin glue application, standard pancreatic closure
Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
2
States / cities
Cleveland, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation Stump
Interventions
Static socket, User adjusted socket, Microprocessor-adjusting sockets
Device
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced May 22, 2026, 1:34 AM EDT
Conditions
ACL Tear
Interventions
ACL reconstruction, Mesenchymal stem cell implantation
Procedure
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
14 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
Conditions
Amputation Stumps
Interventions
Sidekick Stubbies
Device
Lead sponsor
Angela DeCandia
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 20, 2018 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Results available
Conditions
Amputation Stumps, Diabetes Mellitus
Interventions
EBAR Program
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
40 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation
Interventions
Direct Socket TF
Device
Lead sponsor
Össur Iceland ehf
Industry
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
17
States / cities
Mobile, Alabama • Montgomery, Alabama • Opelika, Alabama + 13 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
Conditions
Stenoses, Carotid Artery
Interventions
Carotid endarterectomy with routine shount, Carotid endarterectomy with selective shunt
Procedure
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2013 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Neuroma, Neuroma Amputation, Pain
Interventions
Targeted Muscle Reinnervation, Traction Neurectomy
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
6
States / cities
Chicago, Illinois • Bethesda, Maryland • Columbus, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation, Skin Wound, Stem Cell
Interventions
Autologous Skin Fibroblasts, Placebo
Biological
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Amputation Stump, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Interventions
ICE Condition, Sham Condition
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Holliston, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Amputation, Phantom Limb, Stump Pain
Interventions
perineural ropivacaine, normal saline (placebo)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced May 22, 2026, 1:34 AM EDT
Conditions
Pain, Phantom, Pain, Neuropathic
Interventions
Valproic Acid, Cherry Syrup
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Bethesda, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced May 22, 2026, 1:34 AM EDT