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ClinicalTrials.gov public records Last synced Nov 14, 2026, 8:39 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Apnea of Prematurity Clear all

Conditions: Infant Respiratory Distress Syndrome, Respiratory Insufficiency, Apnea of Prematurity
Interventions: Nasal high frequency ventilation; Other
Lead sponsor: Tarah T Colaizy; Other
Eligibility: 7 Days to 3 Months
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Apnea of Prematurity, Intermittent Hypoxemia, Bradycardia
Interventions: Womb sound recordings; Other
Lead sponsor: Case Western Reserve University; Other
Eligibility: 1 Week to 5 Weeks
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Apnea of Prematurity
Interventions: Caffeine, Sterile Water Placebo; Drug · Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 1 Week to 40 Weeks
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Orange, California

Conditions: Apnea of Prematurity
Interventions: NCPAP as mode for apnea prevention, NIPPV as rescue mode for apnea prevention; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: Not listed
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Neonatal Resuscitation, Apnea Neonatal
Interventions: Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR); Device
Lead sponsor: Michelle Baczynski; Other
Eligibility: 25 Weeks to 29 Weeks
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Apnea of Prematurity, Hypoxia, Bradycardia
Interventions: Vibration; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 1 Week and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Los Angeles, California • Santa Monica, California

Conditions: Bronchopulmonary Dysplasia, Apnea of Prematurity
Interventions: Caffeine, Placebo (dextrose); Drug
Lead sponsor: Wayne State University; Other
Eligibility: Up to 4 Weeks
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Apnea of Prematurity, Desaturation of Blood, Central Apnea, Periodic Breathing, Obstructive Apnea of Newborn
Interventions: Targeting SpO2 at 93-95%, Targeting SpO2 at 90-92%; Other
Lead sponsor: University of Miami; Other
Eligibility: Up to 18 Weeks
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Apnea of Prematurity
Interventions: Not listed
Lead sponsor: Pediatrix; Other
Eligibility: 23 Weeks to 29 Weeks
Enrollment: 160 participants
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Apnea of Prematurity, Respiratory Distress Syndrome
Interventions: Discontinue NCPAP after weaning pressures, Discontinue NCPAP without weaning pressures; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: Not listed
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Obesity, Premature Recovery From Anesthesia
Interventions: Nuvigil, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Apnea of Prematurity
Interventions: Stochastic Resonance Mattress; Device
Lead sponsor: Wyss Institute at Harvard University; Other
Eligibility: Not listed
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Prematurity, Apnea, Respiratory Failure
Interventions: Caffeine citrate, Normal saline; Drug · Other
Lead sponsor: University of Miami; Other
Eligibility: 1 Day to 5 Days
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Apnea of Prematurity
Interventions: Caffeine citrate injection; Drug
Lead sponsor: McMaster University; Other
Eligibility: Up to 10 Days
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2016
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Apnea, Apnea Neonatal, Prematurity
Interventions: PCV13, DTaP, HBV, IPV, Hib; Biological
Lead sponsor: Duke University; Other
Eligibility: 6 Weeks and older
Enrollment: 223 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 4
States / cities: Atlanta, Georgia • Chapel Hill, North Carolina • Durham, North Carolina + 1 more

Conditions: Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
Interventions: Not listed
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 30 Weeks to 83 Months
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Apnea of Prematurity
Interventions: Caffeine Citrate, Placebo; Drug
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: 29 Weeks to 33 Weeks
Enrollment: 827 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 16
States / cities: Birmingham, Alabama • Palo Alto, California • Atlanta, Georgia + 12 more

Conditions: BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity, Hemodynamic Instability, Intubation
Interventions: Caffeine Citrate, Placebo (Normal Saline); Drug
Lead sponsor: Jennifer Shepherd; Other
Eligibility: Up to 1 Day
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Infant,Premature
Interventions: Cardiorespiratory monitoring; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 1 Day to 98 Days
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Neonatal Oxygen Desaturation, Premature, Ventilator Lung; Newborn, Apnea of Prematurity
Interventions: Body positioning; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 1 Minute to 3 Months
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Preterm Labor With Preterm Delivery, Premature Birth, Apnea of Prematurity, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Interventions: Caffeine citrate; Drug
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Gastroesophageal Reflux, Apnea, Bradycardia
Interventions: Erythromycin, Multi-channel intra-luminal impedance (MII) pH monitoring, Placebo (D5W); Drug · Device
Lead sponsor: University of Virginia; Other
Eligibility: 14 Days and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Apnea of Prematurity, Retinopathy of Prematurity, Pain
Interventions: sucrose solution; Dietary Supplement
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 5 Weeks and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 1
States / cities: New York, New York

Conditions: Apnea of Prematurity, Intermittent Hypoxemia, Bronchopulmonary Dysplasia of Newborn
Interventions: Chinstrap; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 3 Days to 3 Months
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Search by objective public record fields.

Nasal High Frequency Ventilation in Preterm Infants: A Pilot Study

The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm Infants

Caffeine Use in the Management of Preterm Infants

A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants

Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates

Non-invasive Intervention for Apnea of Prematurity

Early Versus Late Caffeine for ELBW Newborns

Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants

The Effect of Standardizing the Definition of a Clinically Significant Cardiopulmonary Event on Length of Stay

A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation

Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients

Stochastic Resonance Mattress (Physiological Interventions) and Biomarkers for Enhancing Neonatal Health

Caffeine to Reduce Mechanical Ventilation in Preterm Infants

Caffeine for Apnea of Prematurity (CAP)

Apnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood Vaccines

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial

Early Caffeine in Preterm Neonates

Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 3

Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants

Pharmacokinetics and Placental Transfer of Caffeine

Study of Erythromycin in GER-Associated Apnea of the Newborn

Use of Sucrose to Relieve Pain During Eye Exams in Infants

Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover Trial