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ClinicalTrials.gov public records Last synced Oct 28, 2026, 4:12 PM EDT

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Showing 1–24 of 167 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Carbon Dioxide Clear all
Not listed Early Phase 1 Interventional

Use of cSVF Via IV Deployment for Residual Lung Damage After Symptomatic COVID-19 Infection

NCT04326036
View directory record Official record
Conditions
Pulmonary Alveolar Proteinosis, COPD, Idiopathic Pulmonary Fibrosis, Viral Pneumonia, Coronavirus Infection, Interstitial Lung Disease
Interventions
Microcannula Harvest Adipose Derived tissue stromal vascular fraction (tSVF), Centricyte 1000, IV Deployment Of cSVF In Sterile Normal Saline IV Solution, Liberase Enzyme (Roche), Sterile Normal Saline for Intravenous Use
Procedure · Device · Drug
Lead sponsor
Black Tie Medical, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Stevensville, Montana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 28, 2026, 4:12 PM EDT
Terminated Not applicable Interventional

Scar Prevention Using Fractional Carbon Dioxide Laser Treatment

NCT01826942
View directory record Official record
Conditions
Scar Prevention
Interventions
Lumenis UltraPulse single fractional CO2 laser treatment thin skin, Single fractional CO2 treatment at surgical area closure procedure on thick skin
Device
Lead sponsor
Lumenis Be Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2014 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Burn Scar Appearance After Treatment With Fractional Carbon Dioxide (CO2) Laser

NCT00969215
View directory record Official record
Conditions
Scars
Interventions
Lumenis fractional carbon dioxide laser
Device
Lead sponsor
Moy-Fincher Medical Group
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2011 · Synced Oct 28, 2026, 4:12 PM EDT
Completed No phase listed Observational

Regulation of Cerebral Blood Flow in Very Low Birth Weight Infants

NCT00579943
View directory record Official record
Conditions
Infant, Very Low Birth Weight, Infant, Premature, Diseases, Cerebral Hemorrhage
Interventions
Not listed
Lead sponsor
University of Arkansas
Other
Eligibility
1 Hour to 7 Days
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2008 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional

Study of the Carbon Dioxide Treatment for Fat Reduction

NCT00974415
View directory record Official record
Conditions
Overweight
Interventions
CO2, Sham
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser

NCT06295471
View directory record Official record
Conditions
Healthy
Interventions
DFG Laser, CO2 Laser, Optical coherence tomography (OCT)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Wearing Masks on End-tidal Carbon Dioxide and Pulse Oximetry

NCT05114993
View directory record Official record
Conditions
Carbon Dioxide
Interventions
wearing a disposable surgical mask
Device
Lead sponsor
Patrick Brooks
Other
Eligibility
2 Years to 80 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Oct 28, 2026, 4:12 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparative Study Using Dermabrasion vs CO2 Laser & Collagen Dressing vs Vaseline Gauze in MKTP

NCT02038257
View directory record Official record
Conditions
Vitiligo, Depigmented Scars, Depigmentation
Interventions
MKTP (melanocyte keratinocyte transplant procedure), Collagen Dressing, Vaseline Impregnated Gauze, Carbon Dioxide Laser, Dermabrasion
Procedure · Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 28, 2026, 4:12 PM EDT
Completed No phase listed Observational Results available

Laser Therapy for Treatment of Urogenital Symptoms in Women

NCT03681678
View directory record Official record
Conditions
Genitourinary System; Disorder, Female, Burning Vagina, Dyspareunia, Irritation; Vagina, Menopause Related Conditions, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Tract Infections, Stress Urinary Incontinence
Interventions
fCO2 Laser Therapy Group
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional

Veress Entry With/Without Concomitant CO2

NCT02896036
View directory record Official record
Conditions
Laparoscopy, Laparoscopic Surgery, Insufflation, Gynecologic Surgical Procedures
Interventions
Veress needle entry with concomitant CO2, Veress needle entry with subsequent CO2
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2018 · Synced Oct 28, 2026, 4:12 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Brain Blood Vessel Responses to Changes in Blood Flow

NCT06629077
View directory record Official record
Conditions
Magnetic Resonance Imaging, Cerebrovascular Circulation
Interventions
MRI, Prazosin, Placebo
Device · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years to 69 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Completed No phase listed Observational

Respiration Measured Via End-tidal CO2 and Spirometry Study (RESPI)

NCT07537478
View directory record Official record
Conditions
Respiration Rate Detection
Interventions
Wearable Respiration mask - exercise, Wearable respiration Mask
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional

A Simple Clinical Maneuver to Reduce Laparoscopy Induced Shoulder Pain

NCT00575237
View directory record Official record
Conditions
Shoulder Pain
Interventions
Recruitment manouver
Procedure
Lead sponsor
Phelps, Paul, M.D.
Individual
Eligibility
15 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Wildomar, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2007 · Synced Oct 28, 2026, 4:12 PM EDT
Terminated Not applicable Interventional Results available

Polar Wand Carbon Dioxide Cryotherapy for Barrett's Esophagus

NCT01477177
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Polar Wand carbon dioxide cryotherapy
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 98 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2019 · Synced Oct 28, 2026, 4:12 PM EDT
Withdrawn Phase 2 Interventional

Laser Assisted Delivery of Minoxidil in Androgenetic Alopecia

NCT03852992
View directory record Official record
Conditions
Male Pattern Hair Loss, Androgenetic Alopecia, Male Pattern Baldness
Interventions
Post-Laser Minoxidil 2%, At-Home Minoxidil 5%, Laser, Post-laser 5mg minoxidil, Post-laser 10mg minoxidil, Post-laser 20mg minoxidil
Drug · Device
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 28, 2026, 4:12 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment

NCT07210606
View directory record Official record
Conditions
Sleep Disordered Breathing, Able Bodied
Interventions
Trazodone + positive airway pressure (PAP) therapy, Oxygen + positive airway pressure (PAP) therapy
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

In-vivo Analysis and Clinical Evaluation of the Performance of a Fractional CO2 Laser System (eMatrixCO2)

NCT00992277
View directory record Official record
Conditions
Aesthetic Dermatology
Interventions
Ablation and skin resurfacing
Procedure
Lead sponsor
Syneron Medical
Industry
Eligibility
20 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
3
States / cities
San Diego, California • Tustin, California • Saint Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TR-987 vs. Placebo Following Fractionated CO2 Laser Resurfacing of the Chest

NCT02681224
View directory record Official record
Conditions
Exposure Laser
Interventions
TR987 Gel with Silon Bandage, TR987 without Silon Bandage, Placebo Gel with Silon Bandage, Placebo Gel without Silon Bandage
Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Phase 2 Interventional Results available

Abnormal Ventilatory Response to Carbon Dioxide: a Potential Biomarker for Seizure Induced Respiratory Depression & Modification by SSRI

NCT02929667
View directory record Official record
Conditions
Epilepsy, SUDEP
Interventions
Fluoxetine, Placebo
Drug
Lead sponsor
Rup Kamal Sainju
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional

Carbon Dioxide Insufflation Versus Conventional Air Insufflation

NCT02790359
View directory record Official record
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 13, 2019 · Synced Oct 28, 2026, 4:12 PM EDT
Withdrawn Not applicable Interventional

A Single-Blind, Randomized Study to Compare fCO2 Laser Therapy Versus Sham for Treatment of SUI in Women

NCT04253067
View directory record Official record
Conditions
Stress Urinary Incontinence, Urinary Incontinence
Interventions
Active fCO2 laser treatment, Sham fCO2 laser treatment
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 75 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 28, 2026, 4:12 PM EDT
Completed Not applicable Interventional

U-POEM vs CO2-POEM

NCT06918730
View directory record Official record
Conditions
Esophageal Motility Disorders
Interventions
U-POEM, CO2-POEM
Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Compression and CO2 Laser for Leg Wounds

NCT04198454
View directory record Official record
Conditions
Wound Healing
Interventions
Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser
Other · Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 28, 2026, 4:12 PM EDT
Recruiting Phase 3 Interventional

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

NCT05379153
View directory record Official record
Conditions
Vaginal Atrophy, Breast Carcinoma
Interventions
Laser Therapy, Sham Intervention, Questionnaire Administration, Quality of Life Assessment
Device · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
22 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Des Moines, Iowa • Ann Arbor, Michigan • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 28, 2026, 4:12 PM EDT