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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Carotid Artery Diseases Clear all
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function

NCT03062878
View directory record Official record
Conditions
Breast Cancer, Lymphoma, Chemotherapy Effect
Interventions
Arterial blood pressure, Vascular Ultrasound, Venous blood sample, Skin microcirculatory blood flow
Other
Lead sponsor
Carl Ade, M.S., Ph.D.
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 21, 2026, 1:27 PM EDT
Terminated Phase 2 Interventional Results available

Dose-Finding, Feasibility Study of Optison in Contrast Enhanced U/S for the Detection of Carotid Artery Disease

NCT01394926
View directory record Official record
Conditions
Carotid Artery Disease
Interventions
Optison
Drug
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 1, 2014 · Synced Jul 21, 2026, 1:27 PM EDT
Terminated Phase 2 Interventional Results available

TRACER RGD-K5 Carotid Plaque Imaging Study

NCT01968226
View directory record Official record
Conditions
Carotid Artery Disease, Carotid Stenosis
Interventions
[F-18] RDG-K5
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Phase 3 Interventional

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)

NCT03121209
View directory record Official record
Conditions
Internal Carotid Artery Stenosis, Cognitive Impairment
Interventions
Revascularization, Intensive Medical Management (IMM) alone
Procedure · Other
Lead sponsor
Columbia University
Other
Eligibility
35 Years to 86 Years
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
56
States / cities
Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 45 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 21, 2026, 1:27 PM EDT
Terminated Phase 2 Interventional

Effect of ARC1779 on Cerebral Microembolism in Patients Undergoing Carotid Endarterectomy

NCT00742612
View directory record Official record
Conditions
Intracranial Embolism, Cerebral Thromboembolism, Carotid Stenosis
Interventions
ARC1779 Injection, Placebo (normal saline)
Drug
Lead sponsor
Archemix Corp.
Industry
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Hackensack, New Jersey • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2010 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

GORE Flow Reversal System and GORE Embolic Filter Extension Study

NCT01343667
View directory record Official record
Conditions
Carotid Stenosis, Constriction, Pathologic, Carotid Artery Diseases, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Arterial Occlusive Diseases, Vascular Diseases, Cardiovascular Diseases, Pathological Conditions, Anatomical
Interventions
Gore Flow Reversal System, Gore Embolic Filter
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
1,397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
39
States / cities
Flagstaff, Arizona • Newport Beach, California • San Francisco, California + 34 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Jul 21, 2026, 1:27 PM EDT
Active, not recruiting No phase listed Observational

CREST-2 Long-term Observational Extension Study

NCT05465122
View directory record Official record
Conditions
Stenoses, Carotid
Interventions
Carotid Endarterectomy, FDA-approved carotid stents, Intensive Medical Management
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
35 Years and older
Enrollment
2,480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
61
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis (Volunteer - BioD and Safety Study)

NCT02498379
View directory record Official record
Conditions
Atherosclerosis
Interventions
Cu[64]-25%CANF-Comb
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Jul 21, 2026, 1:27 PM EDT
Completed No phase listed Observational

Cognitive Outcome After Carotid Surgery

NCT02118233
View directory record Official record
Conditions
Carotid Stenosis
Interventions
Not listed
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
3
States / cities
Burlington, Massachusetts • Buffalo, New York • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Jul 21, 2026, 1:27 PM EDT
Completed No phase listed Observational

Safety and Feasibility of the Infinity Catheter for Radial Access

NCT04553549
View directory record Official record
Conditions
Brain Tumor, Stroke, Acute, Brain Aneurysm, Intracranial Arteriovenous Malformations, Carotid Stenosis, Cavernous Sinus Thrombosis
Interventions
Transradial approach
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Jul 21, 2026, 1:27 PM EDT
Completed No phase listed Observational

SAPPHIRE Worldwide: Stenting and Angioplasty With Protection in Patients At High-Risk for Endarterectomy

NCT00403078
View directory record Official record
Conditions
Carotid Artery Disease
Interventions
Not listed
Lead sponsor
Cordis US Corp.
Industry
Eligibility
18 Years and older
Enrollment
21,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
5
States / cities
Newark, Delaware • West Des Moines, Iowa • Lincoln, Nebraska + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2020 · Synced Jul 21, 2026, 1:27 PM EDT
Withdrawn Phase 2 Interventional

Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation

NCT02995642
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal, Carotid Atherosclerosis
Interventions
18F-FPPRGD2, Positron emission tomography, Computed tomography, Magnetic Resonance Imaging
Drug · Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Phase 4 Interventional Results available

Assess the Penumbra System in the Treatment of Acute Stroke

NCT01429350
View directory record Official record
Conditions
Ischemic Stroke
Interventions
intravenous (IV) recombinant human tissue plasminogen activator (rtPA), Penumbra System
Drug · Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
4
States / cities
Denver, Colorado • Gainesville, Florida • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Jul 21, 2026, 1:27 PM EDT
Completed No phase listed Observational Results available

Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates

NCT01353196
View directory record Official record
Conditions
Cognitive Manifestations
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Jul 21, 2026, 1:27 PM EDT
Not listed Not applicable Interventional

Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Patients

NCT00883402
View directory record Official record
Conditions
Carotid Stenosis
Interventions
CEA, CAS
Procedure
Lead sponsor
University of Oxford
Other
Eligibility
18 Years and older
Enrollment
3,638 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Not applicable Interventional

A Comparison of Cognitive Function After Carotid Endarterectomy and Stenting

NCT02220595
View directory record Official record
Conditions
Carotid Artery Occlusive Disease
Interventions
Carotid endarterectomy vs. carotid stenting
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
30 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Jul 21, 2026, 1:27 PM EDT
Terminated Phase 3 Interventional

Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant

NCT00228176
View directory record Official record
Conditions
Carotid Artery Plaque, Arteriosclerosis, Obesity, Metabolic Syndrome X
Interventions
Rimonabant, Placebo (for Rimonabant)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
55 Years and older
Enrollment
661 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 19, 2016 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Phase 2 Interventional Results available

NeuroCognition After Carotid Recanalization

NCT04219774
View directory record Official record
Conditions
Cognition Disorder, Stroke, Occlusion Carotid
Interventions
Endovascular intervention, Aspirin and Clopidogrel (maximal medical Therapy)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
21 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Jul 21, 2026, 1:27 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Exercise and Carotid Artery Function in Metabolic Syndrome

NCT07430839
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
exercise, Diagnostics, Inhaled CO2-mixed air
Behavioral · Diagnostic Test · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jul 21, 2026, 1:27 PM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

The Effects of Omega-3 Fatty Acids on Metabolic Syndrome

NCT00350194
View directory record Official record
Conditions
Metabolic Syndrome X
Interventions
Omega-3 fatty acids
Dietary Supplement
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 1, 2012 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Phase 3 Interventional

Carotid Revascularization With ev3 Arterial Technology Evolution (CREATE) Trial

NCT00619775
View directory record Official record
Conditions
Carotid Artery Disease
Interventions
PROTÉGÉ® GPS™ and PROTÉGÉ® RX Carotid Stent Systems and Spider Embolic Protection Device
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years and older
Enrollment
419 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
31
States / cities
Mesa, Arizona • La Jolla, California • Mountain View, California + 26 more
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Jul 21, 2026, 1:27 PM EDT
Completed No phase listed Observational

Aneurysms and Carotid Artery Block in Newborns

NCT00646672
View directory record Official record
Conditions
Cerebrovascular Disorder
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 25 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 1:27 PM EDT
Terminated Phase 2Phase 3 Interventional

Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.

NCT00151788
View directory record Official record
Conditions
Atherosclerosis, Heterozygous Familial Hypercholesterolemia
Interventions
Pactimibe sulfate
Drug
Lead sponsor
Daiichi Sankyo
Industry
Eligibility
40 Years to 75 Years
Enrollment
796 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
8
States / cities
Santa Ana, California • Chicago, Illinois • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2012 · Synced Jul 21, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeting the Carotid Bodies to Reduce Disease Risk Along the Diabetes Continuum

NCT05219994
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Hyperoxia Exposure, Normoxia Exposure
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jul 21, 2026, 1:27 PM EDT