Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
Public ClinicalTrials.gov record NCT05611242. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective is to establish the efficacy of intra-arterial (IA) mechanical thrombectomy (MT) with extracranial proximal carotid artery acute stenting versus non-stenting approaches in patients with acute ischemic stroke (AIS) from intracranial vessel occlusion (IVO) in the anterior circulation and have a proximal carotid occlusive disease (occlusion or severe stenosis).
Study identification
- NCT ID
- NCT05611242
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 404 participants
Conditions and interventions
Conditions
Interventions
- MT+CAS with IV-AP Procedure
- MT+CAS with PO-AP Procedure
- MT+CAT with PO-AP Procedure
Procedure
Eligibility (public fields only)
- Age range
- 18 Years to 79 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 7, 2024
- Primary completion
- Mar 7, 2026
- Completion
- May 7, 2027
- Last update posted
- Dec 16, 2025
2024 – 2027
United States locations
- U.S. sites
- 51
- U.S. states
- 24
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mobile Infirmary Medical Center | Mobile | Alabama | 36607 | Recruiting |
| Glendale Adventist Medical Center | Glendale | California | 91206 | Recruiting |
| University of California, Irvine | Irvine | California | 92697 | Recruiting |
| Pomona Valley | Pomona | California | 91767 | Recruiting |
| Sutter Institute for Medical Research | Sacramento | California | 95816 | Not yet recruiting |
| California Pacific Medical Center/Mils Peninsula Medical Center | San Francisco | California | 94107 | Recruiting |
| Boca Raton - Baptist Health | Boca Raton | Florida | 33486 | Recruiting |
| Delray Medical Center | Delray Beach | Florida | 33484 | Recruiting |
| Baptist Health Research Institute | Jacksonville | Florida | 32207 | Recruiting |
| University of Florida Health Jacksonville | Jacksonville | Florida | 32209 | Recruiting |
| University of Miami School of Medicine | Miami | Florida | 33136 | Recruiting |
| Orlando Health, Inc. | Orlando | Florida | 32806 | Recruiting |
| University of South Florida | Tampa | Florida | 33606 | Recruiting |
| St. Mary's Medical Center | West Palm Beach | Florida | 33407 | Recruiting |
| Piedmont Healthcare | Atlanta | Georgia | 30309 | Recruiting |
| WellStar Health System, Inc | Marietta | Georgia | 30062 | Recruiting |
| Ascension/Alexian Brothers Health System | Chicago | Illinois | 60606 | Recruiting |
| University of Chicago | Chicago | Illinois | 60637 | Recruiting |
| Northwestern Medicine Central DuPage Hospital | Winfield | Illinois | 60190 | Recruiting |
| Indiana University Health Methodist Hospital | Indianapolis | Indiana | 46202 | Recruiting |
| Munster Community Hospital | Munster | Indiana | 46321 | Recruiting |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | Recruiting |
| Baptist Healthcare Systems, Inc | Lexington | Kentucky | 40299 | Recruiting |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | Recruiting |
| Louisiana State University Health Sciences Center at Shreveport | Shreveport | Louisiana | 71103 | Recruiting |
| Boston Medical Center | Boston | Massachusetts | 02118 | Recruiting |
| University of Massachusetts | Worcester | Massachusetts | 01655 | Recruiting |
| McLaren Flint | Flint | Michigan | 48532 | Recruiting |
| Bronson Methodist Hospital/Western Michigan University Homer Stryker M.D. School of Medicine | Kalamazoo | Michigan | 49007 | Recruiting |
| Michigan State University | Lansing | Michigan | 48912 | Recruiting |
| McLaren Macomb | Mount Clemens | Michigan | 48043 | Recruiting |
| SSM Health DePaul Hospital | St Louis | Missouri | 63044 | Recruiting |
| JFK University Medical Center | Edison | New Jersey | 08837 | Recruiting |
| Rutgers, The State University | Piscataway | New Jersey | 08854 | Recruiting |
| Albany Medical College | Albany | New York | 12208 | Recruiting |
| Northwell Health- South Shore University Hospital | Bay Shore | New York | 11706 | Recruiting |
| Mount Sinai Hospital | New York | New York | 10029 | Recruiting |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | Recruiting |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | Recruiting |
| Mercy Health St. Vincent Medical Center | Toledo | Ohio | 43608 | Recruiting |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Allegheny Health Network Research Institute | Pittsburgh | Pennsylvania | 15212 | Recruiting |
| WellSpan Health | York | Pennsylvania | 17403 | Recruiting |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Recruiting |
| Semmes-Murphey Foundation | Memphis | Tennessee | 38120 | Recruiting |
| DHR Health Institute for Research and Development | Edinburg | Texas | 78539 | Not yet recruiting |
| HCA Houston Kingwood | Houston | Texas | 77004 | Recruiting |
| University of Utah | Salt Lake City | Utah | 84112 | Recruiting |
| Valley Medical Center | Renton | Washington | 98055 | Recruiting |
| University of Washington | Seattle | Washington | 98195 | Not yet recruiting |
| West Virginia Univeristy | Morgantown | West Virginia | 26506 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05611242, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 16, 2025 · Synced Sep 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05611242 live on ClinicalTrials.gov.