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Conditions: Infection, Hospital
Interventions: Passive disinfection device; Device
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Maplewood, Minnesota

Conditions: Kidney Failure, Chronic, Catheter-Related Infections
Interventions: Neutrolin, Heparin; Drug
Lead sponsor: CorMedix Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 806 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 5
States / cities: Riverside, California • San Dimas, California • Miami Gardens, Florida + 2 more

Conditions: CLABSI - Central Line Associated Bloodstream Infection
Interventions: Sodium Citrate 4% Inj Syringe 3Ml; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: Up to 18 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Central Venous Catheter Thrombosis, Central Venous Catheter Associated Bloodstream Infection
Interventions: alteplase (recombinant t-PA), Heparin; Biological · Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: Up to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Kidney Failure, Chronic, Hemodialysis Complication, Hemodialysis Catheter Infection, Hemodialysis Access Failure, Central Venous Catheter Related Bloodstream Infection, End Stage Renal Disease
Interventions: Pristine™ Long-Term Hemodialysis Catheter; Device
Lead sponsor: C. R. Bard; Industry
Eligibility: 18 Years and older
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 6
States / cities: Dothan, Alabama • New Haven, Connecticut • Shreveport, Louisiana + 3 more

Conditions: Falls Injury, Readmission Rates, CLABSI - Central Line Associated Bloodstream Infection, Catheter Associated Urinary Tract Infection, Hospital Acquired Pressure Injury, Venous Thromboembolism (VTE), Nurses, Satisfaction, Patient, Length of Stay
Interventions: Co-Care; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Central Line-associated Bloodstream Infection (CLABSI)
Interventions: CHG Education; Behavioral
Lead sponsor: Duke University; Other
Eligibility: Not listed
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Durham, North Carolina • Raleigh, North Carolina

Conditions: Central Line Associated Bloodstream Infections (CLABSI), Bone Marrow Transplant
Interventions: Parafilm; Device
Lead sponsor: Emory University; Other
Eligibility: Up to 21 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Vascular Access Complication, Central Line Complication, Central Line-Associated Infection, Superficial Vein Thrombosis, Deep Vein Thrombosis
Interventions: Midline catheter; Device
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Staphylococcus Aureus
Interventions: AZD7760, Placebo; Drug · Other
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 231 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 43
States / cities: Huntsville, Alabama • Chula Vista, California • Glendale, California + 38 more

Conditions: Central Line Bloodstream Infections
Interventions: Silver Alginate; Device
Lead sponsor: Baylor Research Institute; Other
Eligibility: 1 Day to 3 Weeks
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Healthy
Interventions: CVC Train the Trainer; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Central Line-associated Bloodstream Infection (CLABSI)
Interventions: Not listed
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Central Line-Associated Bloodstream Infection (CLABSI), Venous Thromboembolism, Patient Fall, Catheter-Associated Infection, Severe Hypoglycemia, Opioid-Related Severe Adverse Drug Event, Hospital Acquired Pressure Ulcer, Adverse Drug Event, Severe Hospital Acquired Delerium, Rapid Response Related to Arrhythmia
Interventions: Patient Safety health information technology; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 99 Years
Enrollment: 21,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Catheter-related Bloodstream Infection (CRBSI) Nos, Bloodstream Infection Due to Central Venous Catheter, Bloodstream Infection Due to Hickman Catheter
Interventions: Ethanol, Heparin Lock, Normal Saline; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 90 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Bloodstream Infection
Interventions: 70% ethanol, heparin flush solution; Drug
Lead sponsor: Baystate Medical Center; Other
Eligibility: 6 Months to 23 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Catheter-Related Infections
Interventions: (taurolidine and heparin) catheter lock solution, Standard of Care; Drug
Lead sponsor: CorMedix Therapeutics; Industry
Eligibility: Up to 17 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 6
States / cities: Birmingham, Alabama • Phoenix, Arizona • Palo Alto, California + 3 more

Conditions: Bacteremia
Interventions: Heparin 1000U/mL, 4% Sodium Citrate with Gentamicin 320 mcg/mL; Drug
Lead sponsor: Satellite Healthcare; Other
Eligibility: Not listed
Enrollment: 303 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2010
U.S. locations: 1
States / cities: Mountain View, California

Conditions: Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter
Interventions: Cook Spectrum Pediatric Central Venous Catheter Anti-microbial Impregnated Polyurethane and Arrow Pediatric Central Venous Catheter; Device
Lead sponsor: Corewell Health West; Other
Eligibility: Up to 18 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Central Line-associated Bloodstream Infection (CLABSI), Ventilator Associated Pneumonia
Interventions: Collaborative Group, Tool Kit; Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 1 Year and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Bacterial Infections
Interventions: Central Venous Catheter; Device
Lead sponsor: Angiotech Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 960 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 21
States / cities: Birmingham, Alabama • Orange, California • San Diego, California + 17 more

Conditions: Central Line Complication, Central Line Infection, Central Line-Associated Infection, Central Line Sepsis, Short Gut Syndrome, Quality of Life, Pediatric Disorder
Interventions: Wearable Central Line Securement Device (Vest), Traditional Securement Dressing; Device · Other
Lead sponsor: Ryan St. Pierre-Hetz; Other
Eligibility: 0 Years to 18 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Central Line-Associated Bloodstream Infection
Interventions: ethanol, heparin-saline placebo; Drug
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 6 Months to 25 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Catheter-Related Infections
Interventions: Ethanol lock, Heparin lock; Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Palo Alto, California

Search by objective public record fields.

Passive Disinfection Cap Compliance Study

Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection

Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition

t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection

The Pristine Post-Market Study

Duke Virtual IntEgrated Workflow

Implementation Program to Improve CHG Bathing Compliance

Parafilm to Prevent CLABSI in Pediatric Patients Undergoing HCT

Novel Strategy to Encourage Early Removal of Central Venous Catheters

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

The Effectiveness of Silver Alginate (Algidex) Patch in the Prevention of Central Line Infections in Very Low Birth Weight Infants

Central Venous Catheter Insertion Train the Trainer

Central Line-Associated Bloodstream Infection QI Project

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered

Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition

Ethanol Locks for the Treatment of Central Venous Line Infections

Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age

Prophylactic Antimicrobial Catheter Lock

Study of the Use of Coated Venous Catheters in the Critically Ill Child

Safe Critical Care: Testing Improvement Strategies

Safety and Efficacy Study of Angiotech Central Venous Catheter to Prevent Bacterial Catheter Colonization

Innovative Central Line Securement Device in the Pediatric Population

Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection

Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections