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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:50 AM EST

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Showing 1–24 of 60 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Circadian Dysregulation Clear all

Conditions: Circadian Dysregulation
Interventions: Meal schedule; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 35 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Eating Disorder, Binge Eating, Circadian Dysregulation
Interventions: Bright Light Exposure, Natural Light Exposure; Device
Lead sponsor: University of Wyoming; Other
Eligibility: 18 Years and older · Female only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Laramie, Wyoming

Conditions: Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm, Sleep Disorders, Intrinsic, Advanced Sleep Phase Syndrome (ASPS), Advanced Sleep Phase Syndrome, Advanced Sleep Phase, Delayed Sleep Phase, Delayed Sleep Phase Syndrome, Non-24 Hour Sleep-Wake Disorder, Irregular Sleep-Wake Syndrome, Shift-Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Delayed Phase Sleep Syndrome
Interventions: sleep-wake timing, constant routine; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Disorder, Circadian Dysregulation, Habit, Good Sleep
Interventions: RISE-UP Routine, Awareness Training, Vigilant Monitoring, Implementation Intentions, Values-based Approach, Brief Education; Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 18 Years and older
Enrollment: 286 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Obesity, Hypertension, Circadian Dysregulation, Salt; Excess
Interventions: Oral sodium supplementation; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 25 Years to 45 Years
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Circadian Rhythm Disorders
Interventions: Blue light-blocking goggles, Clear goggles; Other
Lead sponsor: West Virginia University; Other
Eligibility: 45 Years to 75 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Dementia, Alzheimer Disease, Dementia, Vascular, Sleep Disorders, Circadian Dysregulation
Interventions: Zolpidem CR, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 60 Years to 99 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Apnea Syndromes, Insomnia, Insufficient Sleep Syndrome, Circadian Rhythm Disorders
Interventions: Not listed
Lead sponsor: Dayzz Live Well Ltd.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sleep Disorder, Circadian Dysregulation
Interventions: Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C), Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C), Usual Care Delayed Treatment; Behavioral · Other
Lead sponsor: University of California, Berkeley; Other
Eligibility: 18 Years and older
Enrollment: 489 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 10
States / cities: Concord, California • Fairfield, California • Goleta, California + 7 more

Conditions: Circadian Rhythm Disorders, Sleep
Interventions: Bright Light; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: Not listed
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Circadian Dysrhythmia, Sleep Disturbance, Critical Illness, Children, Only
Interventions: Daytime light exposure, Daytime restricted feeding; Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 3 Years to 6 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Depression, Postpartum Depression, Prenatal Disorder, Circadian Dysregulation, Pregnancy Related, Sleep Disturbance
Interventions: Personalized Integrated Chronotherapy; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 3
States / cities: Glen Oaks, New York • Chapel Hill, North Carolina • Providence, Rhode Island

Conditions: Cancer-related Problem/Condition, Depression, Circadian Rhythm Disorders
Interventions: PEI Experimental Light, Comparison Light; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 21 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Sleep, Metabolism Changes, Circadian Rhythm, Lifestyle Factors, Sleep Hygiene, Sleep Hygiene, Inadequate, Sleep Deprivation, Insufficient Sleep, Circadian Misalignment, Circadian Dysregulation, Light Exposure
Interventions: Central Clock Misalignment, Peripheral Misalignment; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 35 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Circadian Rhythm Disorders
Interventions: Not listed
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Insomnia, Hypersomnia, Cognitive Impairment, Cognitive Decline, Mild Cognitive Impairment, Frontotemporal Dementia, Neurocognitive Disorders, Vascular Dementia, Sleep Disorder, Memory Impairment
Interventions: Attention-Control Condition, Timed Activity Intervention; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 110 Years
Enrollment: 421 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Circadian Rhythm Disorders
Interventions: Daytime Bright Light, Usual Light; Device
Lead sponsor: Yale University; Other
Eligibility: 50 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cardiovascular Risk Factor, Circadian Dysregulation, Obesity
Interventions: Positron Emission Tomography (PET) scanning of cardiac function at 3 time points across the 24 hour circadian cycle; Combination Product
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 25 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Non-24-Hour Sleep-Wake Disorder
Interventions: tasimelteon, Placebo; Drug
Lead sponsor: Vanda Pharmaceuticals; Industry
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 22
States / cities: Phoenix, Arizona • Orange, California • Palo Alto, California + 19 more

Conditions: Breast Cancer
Interventions: Urine sample, Electrode sleep recorder, phlebotomy; Procedure · Device
Lead sponsor: Stanford University; Other
Eligibility: 45 Years to 75 Years · Female only
Enrollment: 141 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Stanford, California

Conditions: Shift-Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Sleep Disorders, Circadian Rhythm, Sleep Disorders, Intrinsic, Advanced Sleep Phase Syndrome (ASPS), Advanced Sleep Phase Syndrome, Advanced Sleep Phase, Delayed Sleep Phase, Delayed Sleep Phase Syndrome, Non-24 Hour Sleep-Wake Disorder, Irregular Sleep-Wake Syndrome
Interventions: Short Nap Intervention, No Nap Intervention; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 50 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Insomnia, Hypersomnia, Cognitive Impairment, Cognitive Decline, Mild Cognitive Impairment, Frontotemporal Dementia, Neurocognitive Disorders, Vascular Dementia, Sleep Disorder, Memory Impairment
Interventions: Tailored music listening intervention; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 110 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Circadian Dysregulation
Interventions: Habit-based Sleep Health Intervention, Text messaging intervention; Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 18 Years to 30 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Circadian Rhythm Disorders
Interventions: LML134, Placebo; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 8
States / cities: Los Angeles, California • San Diego, California • Miami, Florida + 5 more

Search by objective public record fields.

Development of Countermeasures Against Adverse Metabolic Effects of Shift Work

A Pilot Test of Mood and Circadian Rhythm Mechanisms Driving Binge Eating

Biomarkers for Circadian Timing in Healthy Adults

Mini-treatment Experiments to Clarify How to Assist People to Habit Formation

Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans

Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH

Zolpidem CR and Hospitalized Patients With Dementia

Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire

Implementing and Sustaining a Sleep Treatment to Improve Community Mental Part 1: Implementation Health Outcomes

The Effects of Bright Light Exposure on ICU Nurses

PICU-related Sleep and Circadian Dysregulation Pilot Study

Personalized Integrated Chronotherapy for Perinatal Depression

Programmed Environmental Illumination (PEI) of Hospital Rooms to Prevent/Reduce Cancer-Related Fatigue

Nighttime Synchrony of Your Nutrition and Circadian Health

Identification of Novel Circadian Biomarkers

The Healthy Patterns Sleep Study

Daytime Bright Light, Circadian Abnormalities, and Delirium in Medical ICU Patients

Body Weight, Sleep, and Heart Health

Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder

Sleep, Circadian Hormonal Dysregulation, and Breast Cancer Survival

Breath Biomarkers for Sleep Loss and Circadian Timing

The Music, Sleep and Dementia Study

Maintaining Behavior Change: An Evaluation of a Habit-based Sleep Health Intervention

A Study to Assess the Wakefulness Promoting Effect, Safety, Tolerability, and Pharmacokinetics (PK) of LML134 in Shift Work Disorder