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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cognitive Function Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Cognition Via Exercise and Nutrition

NCT05472831
View directory record Official record
Conditions
Cognitive Function 1, Social
Interventions
BAILAMOS dance program plus MIND diet, BAILAMOS dance program plus Health Education
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
50 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline

NCT04149639
View directory record Official record
Conditions
Healthy
Interventions
NeuroQ
Dietary Supplement
Lead sponsor
LifeSeasons Inc.
Industry
Eligibility
45 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Studio City, California • Flower Mound, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Adult Oxytocin Study

NCT02577575
View directory record Official record
Conditions
Schizophrenia, Oxytocin, Social Cognition
Interventions
Oxytocin, Saline Nasal Spray
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Jul 21, 2026, 4:27 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Mid-frontal Delta/Theta and Cognitive Control

NCT06984757
View directory record Official record
Conditions
Parkinson&Amp;Amp;#39;s Disease (PD)
Interventions
Deep-brain Stimulation, Transcranial Magnetic Stimulation, Transcranial Alternating Current Stimulation
Device
Lead sponsor
Nandakumar Narayanan
Other
Eligibility
18 Years to 99 Years
Enrollment
635 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Jul 21, 2026, 4:27 AM EDT
Completed No phase listed Observational

Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery

NCT01417507
View directory record Official record
Conditions
Adult Diffuse Astrocytoma, Adult Mixed Glioma, Adult Oligodendroglioma, Cognitive/Functional Effects, Neurotoxicity, Psychosocial Effects of Cancer and Its Treatment, Seizure
Interventions
cognitive assessment, magnetic resonance imaging, laboratory biomarker analysis, questionnaire administration, quality-of-life assessment
Procedure · Other
Lead sponsor
Radiation Therapy Oncology Group
Network
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
39
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Jul 21, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional

The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers

NCT07415707
View directory record Official record
Conditions
Aging, Alcohol Drinking
Interventions
Visbiome, Motivational Interviewing, Placebo
Dietary Supplement · Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
65 Years to 84 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Genes, Exercise, Memory and Neurodegeneration

NCT01021644
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
aerobic exercise-training, stretch exercise
Behavioral
Lead sponsor
Howard University
Other
Eligibility
60 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 13, 2014 · Synced Jul 21, 2026, 4:27 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Probing the Role of Feature Dimension Maps in Visual Cognition: Impact of Task Demands (Expt 2.1)

NCT06281457
View directory record Official record
Conditions
Basic Science: Visual Attention in Healthy Participants, Basic Science: Neural Representations of Location
Interventions
Stimulus properties: task-defining feature
Other
Lead sponsor
University of California, Santa Barbara
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Phase 2 Interventional Results available

Improving Cognitive Health in COVID-19 Survivors

NCT04843930
View directory record Official record
Conditions
Cognitive Dysfunction, Covid19
Interventions
AKL-T01
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 89 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Not applicable Interventional

The Effect of Aerobic Exercise on Cognitive Function and Sleep Quality in Individuals With Multiple Sclerosis

NCT01783665
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
aerobic exercise, home exercise program
Other
Lead sponsor
Catherine Siengsukon, PT, PhD
Other
Eligibility
21 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jul 21, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional

Cognition After OSA Treatment Among Native American People (CATNAP)

NCT06227572
View directory record Official record
Conditions
Obstructive Sleep Apnea, Cognitive Change
Interventions
CATNAP MI
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
40 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Eagle Butte, South Dakota
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Jul 21, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy

NCT07675200
View directory record Official record
Conditions
Autophagy, Healthy Aging
Interventions
Spermidine, Placebo
Dietary Supplement
Lead sponsor
Nutraland USA, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Effect of Elderberry Juice on Cognition and Inflammation in Patients With Mild Cognitive Impairment

NCT02414607
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Elderberry Juice, Placebo
Biological · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Phase 2 Interventional Results available

Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study

NCT04080544
View directory record Official record
Conditions
Alzheimer Disease, Cognitive Decline
Interventions
[18F]AV-1451, Positron Emission Tomography
Drug · Procedure
Lead sponsor
Neil M Rofsky, MD, MHA
Other
Eligibility
38 Years to 96 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 21, 2026, 4:27 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Epileptic Hippocampus in Alzheimer's Disease

NCT05899764
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
Brivaracetam
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
45 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

Effects of Aerobic Exercise in Parkinson's Disease

NCT00784563
View directory record Official record
Conditions
Parkinson Disease
Interventions
Continuous training, Interval training
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 80 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 14, 2015 · Synced Jul 21, 2026, 4:27 AM EDT
Terminated Phase 3 Interventional

Global Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's

NCT00322036
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
MPC-7869
Drug
Lead sponsor
Myrexis Inc.
Industry
Eligibility
55 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
23
States / cities
Phoenix, Arizona • Tucson, Arizona • Costa Mesa, California + 20 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2008 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Phase 2 Interventional

Improving Functional Health Literacy in Older Veterans

NCT00038337
View directory record Official record
Conditions
Visual And Cognitive Disability
Interventions
Health Literacy
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Jul 21, 2026, 4:27 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Brain Health Champion Study

NCT03772977
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia, Mild, Subjective Cognitive Decline, At Risk for Cognitive Decline
Interventions
Brain Health Champion
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
60 Years to 79 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 4:27 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Early Detection of Cognitive Decline

NCT05804981
View directory record Official record
Conditions
Cognitive Impairment
Interventions
PRO-CS
Other
Lead sponsor
RAND
Other
Eligibility
65 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Nutraceutical Effects on Long-Term Memory

NCT01963767
View directory record Official record
Conditions
Aging
Interventions
NT-020, Placebo
Drug · Dietary Supplement
Lead sponsor
University of South Florida
Other
Eligibility
65 Years to 85 Years
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Phase 1 Interventional

Allopregnanolone for Mild Cognitive Impairment Due to Alzheimer's Disease or Mild AD

NCT02221622
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Disease
Interventions
Allopregnanolone injection (intravenous solution), Placebo injection (intravenous solution)
Drug
Lead sponsor
University of Southern California
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Jul 21, 2026, 4:27 AM EDT
Completed No phase listed Observational

Cognitive Neuroscience of Autism Spectrum Disorders

NCT01031407
View directory record Official record
Conditions
Asperger's Disorder, Mental Retardation, Children, Adult, Autism Spectrum Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
5 Years to 89 Years
Enrollment
678 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 21, 2026, 4:27 AM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Participants With Early Alzheimer's Disease

NCT02880956
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
ABBV-8E12, placebo for ABBV-8E12
Drug
Lead sponsor
AbbVie
Industry
Eligibility
55 Years to 85 Years
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
38
States / cities
Phoenix, Arizona • Sun City, Arizona • Irvine, California + 31 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Jul 21, 2026, 4:27 AM EDT