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ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer

ClinicalTrials.gov ID: NCT03186638

Public ClinicalTrials.gov record NCT03186638. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 7:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Study of Low-Dose Ibuprofen for Cognitive Problems in Patients With Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This randomized phase II trial studies how well low-dose ibuprofen in improving cognitive impairment in patients with cancer. Anti-inflammatory agents, such as ibuprofen, may slow the decline of cognitive processes and diseases involving the brain.

Study identification

NCT ID
NCT03186638
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
87 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 26, 2017 (Actual)
Primary completion
Mar 30, 2022 (Actual)
Completion
Jun 1, 2022 (Actual)
Last update posted
Sep 25, 2023

2017 – 2022

United States locations

U.S. sites
169
U.S. states
15
U.S. cities
102
Facility City State ZIP Site status
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank California 91505 —
Beebe Medical Center Lewes Delaware 19958 —
Delaware Clinical and Laboratory Physicians PA Newark Delaware 19713 —
Helen F Graham Cancer Center Newark Delaware 19713 —
Medical Oncology Hematology Consultants PA Newark Delaware 19713 —
Regional Hematology and Oncology PA Newark Delaware 19713 —
Christiana Care Health System-Christiana Hospital Newark Delaware 19718 —
Beebe Health Campus Rehoboth Beach Delaware 19971 —
Nanticoke Memorial Hospital Seaford Delaware 19973 —
Christiana Care Health System-Wilmington Hospital Wilmington Delaware 19801 —
Saint Luke's Mountain States Tumor Institute Boise Idaho 83712 —
Saint Luke's Mountain States Tumor Institute - Fruitland Fruitland Idaho 83619 —
Saint Luke's Mountain States Tumor Institute - Meridian Meridian Idaho 83642 —
Saint Luke's Mountain States Tumor Institute - Nampa Nampa Idaho 83686 —
Saint Luke's Mountain States Tumor Institute-Twin Falls Twin Falls Idaho 83301 —
Illinois CancerCare-Bloomington Bloomington Illinois 61704 —
Illinois CancerCare-Canton Canton Illinois 61520 —
Memorial Hospital of Carbondale Carbondale Illinois 62902 —
SIH Cancer Institute Carterville Illinois 62918 —
Illinois CancerCare-Carthage Carthage Illinois 62321 —
Centralia Oncology Clinic Centralia Illinois 62801 —
Cancer Care Specialists of Illinois - Decatur Decatur Illinois 62526 —
Decatur Memorial Hospital Decatur Illinois 62526 —
Crossroads Cancer Center Effingham Illinois 62401 —
Illinois CancerCare-Eureka Eureka Illinois 61530 —
Illinois CancerCare-Galesburg Galesburg Illinois 61401 —
Western Illinois Cancer Treatment Center Galesburg Illinois 61401 —
Illinois CancerCare-Kewanee Clinic Kewanee Illinois 61443 —
Illinois CancerCare-Macomb Macomb Illinois 61455 —
Illinois CancerCare-Ottawa Clinic Ottawa Illinois 61350 —
Illinois CancerCare-Pekin Pekin Illinois 61554 —
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin Illinois 61554 —
Illinois CancerCare-Peoria Peoria Illinois 61615 —
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria Illinois 61615 —
Methodist Medical Center of Illinois Peoria Illinois 61636 —
OSF Saint Francis Medical Center Peoria Illinois 61637 —
Illinois CancerCare-Peru Peru Illinois 61354 —
Valley Radiation Oncology Peru Illinois 61354 —
Illinois CancerCare-Princeton Princeton Illinois 61356 —
Southern Illinois University School of Medicine Springfield Illinois 62702 —
Springfield Clinic Springfield Illinois 62702 —
Memorial Medical Center Springfield Illinois 62781 —
Cancer Care Specialists of Illinois-Swansea Swansea Illinois 62226 —
Southwest Illinois Health Services LLP Swansea Illinois 62226 —
Bronson Battle Creek Battle Creek Michigan 49017 —
Mercy Health Saint Mary's Grand Rapids Michigan 49503 —
Spectrum Health at Butterworth Campus Grand Rapids Michigan 49503 —
Bronson Methodist Hospital Kalamazoo Michigan 49007 —
West Michigan Cancer Center Kalamazoo Michigan 49007 —
Borgess Medical Center Kalamazoo Michigan 49048 —
Mercy Health Mercy Campus Muskegon Michigan 49444 —
Lakeland Hospital Niles Niles Michigan 49120 —
Spectrum Health Reed City Hospital Reed City Michigan 49677 —
Lakeland Medical Center Saint Joseph Saint Joseph Michigan 49085 —
Marie Yeager Cancer Center Saint Joseph Michigan 49085 —
Munson Medical Center Traverse City Michigan 49684 —
Metro Health Hospital Wyoming Michigan 49519 —
Fairview Ridges Hospital Burnsville Minnesota 55337 —
Mercy Hospital Coon Rapids Minnesota 55433 —
Fairview-Southdale Hospital Edina Minnesota 55435 —
Unity Hospital Fridley Minnesota 55432 —
Fairview Maple Grove Medical Center Maple Grove Minnesota 55369 —
Minnesota Oncology Hematology PA-Maplewood Maplewood Minnesota 55109 —
Saint John's Hospital - Healtheast Maplewood Minnesota 55109 —
Abbott-Northwestern Hospital Minneapolis Minnesota 55407 —
Hennepin County Medical Center Minneapolis Minnesota 55415 —
Health Partners Inc Minneapolis Minnesota 55454 —
Monticello Cancer Center Monticello Minnesota 55362 —
New Ulm Medical Center New Ulm Minnesota 56073 —
North Memorial Medical Health Center Robbinsdale Minnesota 55422 —
Park Nicollet Clinic - Saint Louis Park Saint Louis Park Minnesota 55416 —
Regions Hospital Saint Paul Minnesota 55101 —
United Hospital Saint Paul Minnesota 55102 —
Saint Francis Regional Medical Center Shakopee Minnesota 55379 —
Lakeview Hospital Stillwater Minnesota 55082 —
Ridgeview Medical Center Waconia Minnesota 55387 —
Rice Memorial Hospital Willmar Minnesota 56201 —
Minnesota Oncology Hematology PA-Woodbury Woodbury Minnesota 55125 —
Fairview Lakes Medical Center Wyoming Minnesota 55092 —
Parkland Health Center-Bonne Terre Bonne Terre Missouri 63628 —
Saint Francis Medical Center Cape Girardeau Missouri 63703 —
Southeast Cancer Center Cape Girardeau Missouri 63703 —
Capital Region Southwest Campus Jefferson City Missouri 65109 —
Sainte Genevieve County Memorial Hospital Sainte Genevieve Missouri 63670 —
Missouri Baptist Medical Center St Louis Missouri 63131 —
Missouri Baptist Sullivan Hospital Sullivan Missouri 63080 —
Missouri Baptist Outpatient Center-Sunset Hills Sunset Hills Missouri 63127 —
Carson Tahoe Regional Medical Center Carson City Nevada 89703 —
Cancer and Blood Specialists-Henderson Henderson Nevada 89052 —
Comprehensive Cancer Centers of Nevada - Henderson Henderson Nevada 89052 —
Comprehensive Cancer Centers of Nevada-Horizon Ridge Henderson Nevada 89052 —
Las Vegas Cancer Center-Henderson Henderson Nevada 89052 —
OptumCare Cancer Care at Seven Hills Henderson Nevada 89052 —
21st Century Oncology-Henderson Henderson Nevada 89074 —
Comprehensive Cancer Centers of Nevada-Southeast Henderson Henderson Nevada 89074 —
Desert West Surgery Las Vegas Nevada 89102 —
University Medical Center of Southern Nevada Las Vegas Nevada 89102 —
Hope Cancer Care of Nevada Las Vegas Nevada 89103 —
Cancer and Blood Specialists-Shadow Las Vegas Nevada 89106 —
OptumCare Cancer Care at Oakey Las Vegas Nevada 89106 —
21st Century Oncology Las Vegas Nevada 89109 —
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway Las Vegas Nevada 89109 —
HealthCare Partners Medical Group Oncology/Hematology-San Martin Las Vegas Nevada 89113 —
Radiation Oncology Centers of Nevada Southeast Las Vegas Nevada 89119 —
Cancer Therapy and Integrative Medicine Las Vegas Nevada 89121 —
21st Century Oncology-Vegas Tenaya Las Vegas Nevada 89128 —
Ann M Wierman MD LTD Las Vegas Nevada 89128 —
Cancer and Blood Specialists-Tenaya Las Vegas Nevada 89128 —
Comprehensive Cancer Centers of Nevada - Northwest Las Vegas Nevada 89128 —
HealthCare Partners Medical Group Oncology/Hematology-Tenaya Las Vegas Nevada 89128 —
OptumCare Cancer Care at MountainView Las Vegas Nevada 89128 —
Comprehensive Cancer Centers of Nevada-Summerlin Las Vegas Nevada 89144 —
Summerlin Hospital Medical Center Las Vegas Nevada 89144 —
Las Vegas Cancer Center-Medical Center Las Vegas Nevada 89148-2405 —
21st Century Oncology-Fort Apache Las Vegas Nevada 89148 —
Comprehensive Cancer Centers of Nevada Las Vegas Nevada 89148 —
OptumCare Cancer Care at Fort Apache Las Vegas Nevada 89148 —
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills Las Vegas Nevada 89149 —
Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas Nevada 89169 —
University Cancer Center Las Vegas Nevada 89169 —
Hope Cancer Care of Nevada-Pahrump Pahrump Nevada 89048 —
Renown Regional Medical Center Reno Nevada 89502 —
Saint Mary's Regional Medical Center Reno Nevada 89503 —
Radiation Oncology Associates Reno Nevada 89509 —
Cancer Care of Western North Carolina Asheville North Carolina 28801 —
Mission Hospital Inc-Memorial Campus Asheville North Carolina 28801 —
Hope Women's Cancer Centers-Asheville Asheville North Carolina 28816 —
Marietta Memorial Hospital Columbus Ohio 43215 —
Saint Charles Health System Bend Oregon 97701 —
Clackamas Radiation Oncology Center Clackamas Oregon 97015 —
Providence Oncology and Hematology Care Southeast Clackamas Oregon 97015 —
Bay Area Hospital Coos Bay Oregon 97420 —
Providence Newberg Medical Center Newberg Oregon 97132 —
Providence Willamette Falls Medical Center Oregon City Oregon 97045 —
Providence Portland Medical Center Portland Oregon 97213 —
Providence Saint Vincent Medical Center Portland Oregon 97225 —
Christiana Care Health System-Concord Health Center Chadds Ford Pennsylvania 19317 —
Greenville Health System Cancer Institute-Laurens Clinton South Carolina 29325 —
Greenville Health System Cancer Institute-Easley Easley South Carolina 29640 —
Greenville Health System Cancer Institute-Butternut Greenville South Carolina 29605 —
Greenville Health System Cancer Institute-Faris Greenville South Carolina 29605 —
Greenville Memorial Hospital Greenville South Carolina 29605 —
Greenville Health System Cancer Institute-Eastside Greenville South Carolina 29615 —
Greenville Health System Cancer Institute-Greer Greer South Carolina 29650 —
Greenville Health System Cancer Institute-Seneca Seneca South Carolina 29672 —
Greenville Health System Cancer Institute-Spartanburg Spartanburg South Carolina 29307 —
Providence Regional Cancer System-Aberdeen Aberdeen Washington 98520 —
Cancer Care Center at Island Hospital Anacortes Washington 98221 —
PeaceHealth Saint Joseph Medical Center Bellingham Washington 98225 —
Providence Regional Cancer System-Centralia Centralia Washington 98531 —
Swedish Medical Center-Edmonds Edmonds Washington 98026 —
Providence Regional Cancer Partnership Everett Washington 98201 —
Swedish Cancer Institute-Issaquah Issaquah Washington 98029 —
Kadlec Clinic Hematology and Oncology Kennewick Washington 99336 —
Providence Regional Cancer System-Lacey Lacey Washington 98503 —
PeaceHealth Saint John Medical Center Longview Washington 98632 —
Pacific Gynecology Specialists Seattle Washington 98104 —
Swedish Medical Center-Ballard Campus Seattle Washington 98107 —
Kaiser Permanente Washington Seattle Washington 98112 —
Swedish Medical Center-First Hill Seattle Washington 98122-4307 —
Swedish Medical Center-Cherry Hill Seattle Washington 98122-5711 —
Providence Regional Cancer System-Shelton Shelton Washington 98584 —
Rockwood Cancer Treatment Center-DHEC-Downtown Spokane Washington 99204 —
Rockwood North Cancer Treatment Center Spokane Washington 99218 —
Rockwood Clinic Cancer Treatment Center-Valley Spokane Valley Washington 99216 —
PeaceHealth Southwest Medical Center Vancouver Washington 98664 —
Providence Saint Mary Regional Cancer Center Walla Walla Washington 99362 —
Providence Regional Cancer System-Yelm Yelm Washington 98597 —
Cancer Center of Western Wisconsin New Richmond Wisconsin 54017 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03186638, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 25, 2023 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03186638 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →