- Conditions
- Appendicitis, Appendicitis; Perforation
- Interventions
- Lactobacillus rhamnosus GG (LGG) Probiotic, Placebo
- Dietary Supplement
- Lead sponsor
- Children's Health
- Other
- Eligibility
- 4 Years to 18 Years
- Enrollment
- 98 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Dallas, Texas
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Showing 1–10
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- Conditions
- Complicated Appendicitis, Perforated Appendicitis
- Interventions
- ampicillin/clavulanate
- Drug
- Lead sponsor
- Phoenix Children's Hospital
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Perforated Appendicitis
- Interventions
- Initial appendectomy, Interval appendectomy
- Procedure
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Appendicitis, Cholecystitis, Cross Infection, Diverticulitis, Peritonitis
- Interventions
- tigecycline, ceftriaxone sodium + metronidazole
- Drug
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 467 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 46
- States / cities
- Mobile, Alabama • Laguna Hills, California • Los Angeles, California + 38 more
- Conditions
- Appendicitis Acute, Appendicitis Perforated, Appendicitis With Perforation, Appendicitis Suppurative, Appendicitis Gangrenous
- Interventions
- Discharge on oral antibiotics
- Other
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Complicated Appendicitis, Acute Appendicitis
- Interventions
- Ceftriaxone, Intra-peritoneal Fluid Aspiration
- Drug · Procedure
- Lead sponsor
- Johns Hopkins All Children's Hospital
- Other
- Eligibility
- 3 Years to 18 Years
- Enrollment
- 190 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- St. Petersburg, Florida
- Conditions
- Appendicitis Surgery
- Interventions
- Antibiotic
- Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 268 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Appendicitis, Perforated Appendicitis, Ruptured Appendicitis, Complicated Appendicitis
- Interventions
- Early Appendectomy, Interval Appendectomy, Antibiotics
- Procedure · Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 5 Years to 17 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Abscess, Intra-Abdominal, Abdominal Abscess, Abdomen, Acute, Abdominal Pain, Appendicitis, Rupture, Infection, Intestinal Perforation, Peritonitis, Ileus
- Interventions
- Doripenem, Meropenem placebo, Meropenem, Doripenem placebo, Amoxicillin/clavulanate potassium
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 3 Months to 18 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 4
- States / cities
- San Diego, California • Washington D.C., District of Columbia • Cleveland, Ohio + 1 more
- Conditions
- Complicated Intra-abdominal Infections, Complicated Appendicitis
- Interventions
- Eravacycline, Meropenem, Placebo
- Drug
- Lead sponsor
- Tetraphase Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 6
- States / cities
- Los Angeles, California • Indianapolis, Indiana • Las Vegas, Nevada + 3 more