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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:11 AM EDT

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Showing 25–47 of 47 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Compression Fracture Clear all
Completed Not applicable Interventional Results available

Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures

NCT02625766
View directory record Official record
Conditions
LC Pelvic Fracture
Interventions
LC fracture surgical fixation, LC fracture non-operative management
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Indianapolis, Indiana • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Early Phase 1 Interventional

Basivertebral Nerve Block During Vertebral Augmentation: An Alternative Approach to Intraprocedural Pain Management

NCT04774029
View directory record Official record
Conditions
Vertebral Compression, Vertebra Compression Fracture, Vertebral Fracture
Interventions
Basivertebral nerve block, Lidocaine induced basivertebral nerve block
Procedure · Drug
Lead sponsor
Northwell Health
Other
Eligibility
50 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Port Jefferson, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

To Evaluate Success of Cement Treatment of Spinal Compression Fractures

NCT00166374
View directory record Official record
Conditions
Back Pain
Interventions
balloon kyphoplasty
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 20, 2010 · Synced Oct 22, 2026, 2:11 AM EDT
Terminated Not applicable Interventional

Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures

NCT03952182
View directory record Official record
Conditions
Thoracic Fracture, Lumbar Fracture, Compression Fracture of Thoracic Vertebral Body, Compression Fracture of Lumbar Spine, Burst Fracture of Thoracic Vertebra, Burst Fracture of Lumbar Vertebra
Interventions
Spinal Orthosis (LSO, TLSO), No orthosis
Other
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs

NCT01871519
View directory record Official record
Conditions
Compression Fracture of Vertebral Body, Osteoporosis, Cancer
Interventions
Balloon kyphoplasty
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
65 Years and older
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Fremont, California • Sacramento, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Stress Radiography for Pelvic Ring Injuries

NCT05876871
View directory record Official record
Conditions
Pelvic Fracture
Interventions
Pelvic Binder Radiography
Diagnostic Test
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 22, 2026, 2:11 AM EDT
Suspended Not applicable Interventional

A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome

NCT01693094
View directory record Official record
Conditions
Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome, Cubital Tunnel Syndrome, Distal Radius Fractures, Trigger Finger
Interventions
Decision Aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 22, 2026, 2:11 AM EDT
Terminated Not applicable Interventional Results available

Circumferential Vertebral Reconstruction of Osteoporotic Compression Fractures Using a Novel Bipedicular Peek Implant

NCT05337696
View directory record Official record
Conditions
Vertebral Compression Fractures, Osteoporotic Vertebral Compression Fractures
Interventions
Vertebral Implant PEEK Procedure, Vertebral Implant PEEK (VIP) implant
Procedure · Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
50 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
Baltimore, Maryland • New York, New York • Bethlehem, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Phase 3 Interventional Results available

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

NCT01345019
View directory record Official record
Conditions
Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bone Metastases, Multiple Myeloma Bone Lesions
Interventions
Denosumab, Zoledronic acid, Placebo to Denosumab, Placebo to zoledronic acid, Denosumab (for the open-label treatment phase)
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
1,718 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
79
States / cities
Tucson, Arizona • Fayetteville, Arkansas • Anaheim, California + 67 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries

NCT02313675
View directory record Official record
Conditions
Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
Interventions
Acetaminophen, Ketorolac Tromethamine, Saline
Drug
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2018 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Phase 3 Interventional

Cost Effectiveness and Efficacy of Kyphoplasty and Vertebroplasty Trial

NCT00279877
View directory record Official record
Conditions
Osteoporotic Vertebral Compression Fractures
Interventions
Kyphoplasty
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
50 Years to 100 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced Oct 22, 2026, 2:11 AM EDT
Terminated Not applicable Interventional

Humeral Compression/Distraction Device

NCT02861495
View directory record Official record
Conditions
Humeral Fractures
Interventions
Humeral Compression/Distraction (CD) Nail
Device
Lead sponsor
Florida Orthopaedic Institute
Network
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 7, 2018 · Synced Oct 22, 2026, 2:11 AM EDT
Not listed Not applicable Interventional

Biological Allograft Chain Tissue Implant

NCT04064710
View directory record Official record
Conditions
Vertebral Body Compression Fracture(s)
Interventions
Vertebral Body Augmentation, Manual Surgical Instruments
Procedure · Device
Lead sponsor
Lenoss Medical
Industry
Eligibility
50 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
5
States / cities
Denver, Colorado • Manhasset, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 14, 2021 · Synced Oct 22, 2026, 2:11 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures

NCT03651804
View directory record Official record
Conditions
Vertebral Compression Fracture, Facet Joint Pain
Interventions
Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates, Acetaminophen, Physical therapy, Opioids
Procedure · Drug · Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 22, 2026, 2:11 AM EDT
Terminated Not applicable Interventional Results available

Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial

NCT01118715
View directory record Official record
Conditions
Post-traumatic Carpal Tunnel Syndrome, Complex Regional Pain Syndrome, Edema
Interventions
Compression glove
Device
Lead sponsor
J&M Shuler
Industry
Eligibility
18 Years to 85 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 22, 2026, 2:11 AM EDT
Suspended Not applicable Interventional

Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis

NCT06496867
View directory record Official record
Conditions
Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring, Fragility Fracture, Internal Fixation, Nonoperative Care
Interventions
Early Internal Fixation, Nonoperative Care with Early Rehabilitation
Procedure · Other
Lead sponsor
University of Southern California
Other
Eligibility
60 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
12
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Preliminary Review of Cold and Active Compression Therapy for Traumatic Calcaneus or Ankle Fractures

NCT02498717
View directory record Official record
Conditions
Ankle Fractures
Interventions
GameReady, RICE
Device · Other
Lead sponsor
AdventHealth
Other
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 15, 2018 · Synced Oct 22, 2026, 2:11 AM EDT
Terminated Phase 4 Interventional Results available

Anderson Circulating Tumor Cell Burden (CTCB) Study

NCT00819832
View directory record Official record
Conditions
Cancer, Spinal Disease, Vertebral Compression Fractures
Interventions
Kyphoplasty, Vertebroplasty, Cavity SpineWand
Procedure · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Phase 4 Interventional Results available

Medtronic SCORE Study - Study of Curette Use for Obtaining Restoration of Vertebral Body Anatomy in Balloon Kyphoplasty

NCT00810043
View directory record Official record
Conditions
Vertebral Body Compression Fractures (VCFs)
Interventions
Kyphon® Curette
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
3
States / cities
Temple Terrace, Florida • Middletown, Ohio • Burlington, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients

NCT00933036
View directory record Official record
Conditions
Pathologic Fracture of the Vertebra Due to Osteoporosis
Interventions
Crosstrees Pod system for PVA
Device
Lead sponsor
Crosstrees Medical Inc.
Industry
Eligibility
50 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
9
States / cities
Long Beach, California • Washington D.C., District of Columbia • Clearwater, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2014 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation

NCT05205616
View directory record Official record
Conditions
Surgical Complication, Paresthesia, Fracture, Nerve Injury, Nerve Entrapments, Mandibular Nerve Injuries, Mandibular Hypoplasia, Mandibular Retrognathism, Mandibular Hyperplasia, Mandibular Prognathism
Interventions
Sonopet ultrasonic saw, Reciprocating saw
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 22, 2026, 2:11 AM EDT
Active, not recruiting Not applicable Interventional

STAND - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures

NCT04835428
View directory record Official record
Conditions
Vertebral Compression Fracture, Compression Fracture, Vertebral Compression
Interventions
Treatment Group: AGN1 LOEP SV Kit, Control Group: PMMA bone cement
Device
Lead sponsor
AgNovos Healthcare, LLC
Industry
Eligibility
50 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
12
States / cities
Birmingham, Alabama • Mesa, Arizona • Orlando, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 22, 2026, 2:11 AM EDT
Completed Phase 4 Interventional Results available

Unipedicular vs. Bipedicular Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures

NCT01383616
View directory record Official record
Conditions
Vertebral Compression Fracture
Interventions
Kyphon® Balloon Kyphoplasty (Kyphon Inc; Sunnydale, CA)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 100 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 22, 2026, 2:11 AM EDT