- Conditions
- Disc Degeneration
- Interventions
- MSC Treatment group 1 (low dose), MSC Treatment group 2 (high dose), Healthy Control (no treatment)
- Drug · Other
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- 18 Years to 80 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
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Showing 1–24
of 144
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- Trinica Anterior Lumbar Plate System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 3
- States / cities
- Daphne, Alabama • Mobile, Alabama • San Bernardino, California
- Conditions
- Intervertebral Disk Degeneration
- Interventions
- Hyperlordotic Positioning
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- PureGen Osteoprogenitor Cell Allograft
- Biological
- Lead sponsor
- Alphatec Spine, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2011
- U.S. locations
- 3
- States / cities
- Beverly Hills, California • Middleton, Connecticut • Greensboro, North Carolina
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- PDS System, Fusion
- Device
- Lead sponsor
- Interventional Spine, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio • Willow Grove, Pennsylvania
- Conditions
- Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
- Interventions
- Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic, Muscle relaxant during maintenance anesthesia, Pain control with fentanyl, Bispectral Index (BIS) monitoring for depth of anesthesia, Spinal Anesthesia, Midazolam administered during spinal anesthesia, Cerebrospinal fluid collection, Administration of intrathecal morphine
- Procedure
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 218 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Degenerative Disc Disease, Lumbar Disc Disease, Spine Disease, Lumbar Spine Degeneration
- Interventions
- LDGraft, Allograft Bone
- Device · Other
- Lead sponsor
- Locate Bio Pty Ltd
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 3
- States / cities
- Fort Wayne, Indiana • Pinehurst, North Carolina • Nashville, Tennessee
- Conditions
- Degenerative Disc Disease
- Interventions
- Osteocel Plus
- Biological
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years · Female only
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis, Sagittal Deformity
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,050 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 16
- States / cities
- La Jolla, California • Los Alamitos, California • Merced, California + 13 more
- Conditions
- Degenerative Disc Disease (DDD)
- Interventions
- The ReGelTec HYDRAFIL™ System, Conservative Care Management
- Device · Other
- Lead sponsor
- ReGelTec, Inc.
- Industry
- Eligibility
- 22 Years to 85 Years
- Enrollment
- 225 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 15
- States / cities
- Birmingham, Alabama • Santa Monica, California • Walnut Creek, California + 12 more
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- nanOss Bioactive - posterolateral gutter
- Device
- Lead sponsor
- Pioneer Surgical Technology, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 3
- States / cities
- La Jolla, California • San Francisco, California • Columbia, Missouri
- Conditions
- Degenerative Cervical Disc Disease, Degenerative Lumbar Diseases
- Interventions
- Anterior Cervical Interbody Fusion, Anterior lumbar Interbody Fusion, Lateral Lumbar Interbody Fusion
- Device
- Lead sponsor
- Silony Medical GmbH
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- San Ramon, California
- Conditions
- Degenerative Disc Disease, Isthmic-lytic Spondylolisthesis, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Solum IV, Bone Marrow Concentrate with general fluid concentrate (GFC) in Transforaminal Lumbar Interbody Fusion
- Combination Product
- Lead sponsor
- Seton Healthcare Family
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Degenerative Disc Disease
- Interventions
- Aspen Spinous Process System, Pedicle Screw Fixation
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2016
- U.S. locations
- 5
- States / cities
- Pomona, California • Sacramento, California • Kansas City, Kansas + 2 more
- Conditions
- Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity, Lumbar Spondylosis
- Interventions
- Interbody cage (titanium), Interbody cage (PEEK)
- Device
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Degenerative Disc Disease, Spinal Fusion
- Interventions
- TGplPTH1-34 in fibrin, Autologous Bone Graft
- Combination Product · Other
- Lead sponsor
- Kuros Biosurgery AG
- Industry
- Eligibility
- 25 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 15
- States / cities
- La Jolla, California • Boulder, Colorado • Washington D.C., District of Columbia + 11 more
- Conditions
- Spondylosis, Spondylolisthesis, Degenerative Disc Disease
- Interventions
- map3® Cellular Allogeneic Bone Graft
- Other
- Lead sponsor
- RTI Surgical
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 3
- States / cities
- Niagara Falls, New York • Williamsville, New York • Cincinnati, Ohio
- Conditions
- Low Back Pain
- Interventions
- Interspinous process and dynamic stabilization (Wallis System), Total Disc Replacement
- Device
- Lead sponsor
- Zimmer Spine
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 340 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2014
- U.S. locations
- 11
- States / cities
- Beverly Hills, California • Encinitas, California • Boulder, Colorado + 8 more
- Conditions
- Degenerative Disc Disease
- Interventions
- P-15L Bone Graft, Local autologous bone in a TLIF with Instrumentation
- Device · Other
- Lead sponsor
- CeraPedics, Inc
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 290 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2028
- U.S. locations
- 34
- States / cities
- Birmingham, Alabama • Glendale, California • Los Angeles, California + 27 more
- Conditions
- Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
- Interventions
- MagnetOs Flex Matrix, Trinity Elite
- Device
- Lead sponsor
- Kuros Biosurgery AG
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 8
- States / cities
- Hartford, Connecticut • Chicago, Illinois • Columbia, Maryland + 5 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Not listed
- Lead sponsor
- Orthofix Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 9
- States / cities
- South Bend, Indiana • Southfield, Michigan • Missoula, Montana + 5 more
- Conditions
- Degenerative Disc Disease
- Interventions
- Cervical or Lumbar Spinal fusion
- Device
- Lead sponsor
- K2M, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 4
- States / cities
- Shreveport, Louisiana • Cleveland, Ohio • Oklahoma City, Oklahoma + 1 more
- Conditions
- Degenerative Disc Disease (DDD)
- Interventions
- FLD, Control
- Device
- Lead sponsor
- AxioMed Spine Corporation
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2018
- U.S. locations
- 12
- States / cities
- Los Angeles, California • San Diego, California • Loveland, Colorado + 9 more
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- In this evaluation, no interventions are performed. It is a data collection effort only. The "procedure" for this study is the data collection effort.
- Other
- Lead sponsor
- Spineology, Inc
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 197 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 10
- States / cities
- Fremont, California • Loma Linda, California • Napa, California + 7 more