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Completed Phase 1 Interventional

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

ClinicalTrials.gov ID: NCT03347708

Public ClinicalTrials.gov record NCT03347708. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 8, 2026, 3:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Prospective, Randomized, Double-Blinded, Vehicle- and Placebo-Controlled, Multicenter Study to Evaluate the Safety and Preliminary Efficacy of IDCT in Subjects With Single-Level, Symptomatic Lumbar Intervertebral Disc Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to compare the safety and preliminary efficacy of intradiscal injections of two doses of IDCT (Discogenic Cells + Sodium Hyaluronate vehicle) and two controls (saline, Sodium Hyaluronate vehicle) in subjects with chronic low back pain due to Degenerative Disc Disease (DDD) at one lumbar level from L3 to S1.

Study identification

NCT ID
NCT03347708
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
DiscGenics, Inc.
Industry
Enrollment
60 participants

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 25, 2018
Primary completion
Jan 31, 2022
Completion
Nov 9, 2022
Last update posted
Jan 24, 2023

2018 – 2022

United States locations

U.S. sites
14
U.S. states
12
U.S. cities
14
Facility City State ZIP Site status
Alabama Clinical Therapeutics, LLC Birmingham Alabama 35235
University of Southern California Los Angeles California 90033
UC San Diego CIRM Alpha Stem Cell Clinic San Diego California 92037
Source Healthcare Santa Monica California 90403
Otrimed Edgewood Kentucky 41017
Spine Institute of Louisiana Shreveport Louisiana 71101
Orthopedic Center of St. Louis Chesterfield Missouri 63017
Ainsworth Institute of Pain Management New York New York 10022
Carolina Neurosurgery & Spine Associates Charlotte North Carolina 28204
Clinical Investigations, LLC Edmond Oklahoma 73013
Clinical Trials of South Carolina Charleston South Carolina 29406
Semmes Murphey Memphis Tennessee 38120
Physicians' Research Options, LLC Draper Utah 84020
Virginia iSpine Richmond Virginia 23235

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03347708, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 24, 2023 · Synced Sep 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03347708 live on ClinicalTrials.gov.

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