Clinical Trials Finder
Independent ClinicalTrials.gov directory
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced May 22, 2026, 1:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Endodontic Inflammation Clear all
Terminated Not applicable Interventional
View directory record Official record
Conditions
Reversible Pulpitis, Caries
Interventions
Formocresol application after pulpotomy preparation, GENTLEray 980 Soft Tissue diode laser
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
3 Years to 8 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pulpitis, Dental Pulp Diseases, Tooth Diseases
Interventions
Pulpotomy, Extraction and placement of space maintainer
Procedure
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 10 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced May 22, 2026, 1:34 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Symptomatic Irreversible Pulpitis
Interventions
Sodium bicarbonate, Lidocaine w/ epi, Articaine w/ epi, Mepivacaine plain
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced May 22, 2026, 1:34 AM EDT
Completed Phase 4 Interventional
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Bupivacaine
Drug
Lead sponsor
University of Maryland
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 30, 2018 · Synced May 22, 2026, 1:34 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Irreversible Pulpitis, Apical Periodontitis, Pulpal Necrosis
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 89 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced May 22, 2026, 1:34 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Irreversible Pulpitis
Interventions
RCT, Pulpotomy
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years to 99 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Deep Dental Caries
Interventions
Indirect Pulp capping-Resin-modified calcium silicate - TheraCal, Indirect Pulp capping-Calcium hydroxide - Dycal, Indirect Pulp capping-Resin-based dentin bonding agent, Direct Pulp capping-Resin-modified calcium silicate - TheraCal, Direct Pulp capping-Calcium hydroxide - Dycal
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 64 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Interventions
Multisonic vs Sonic activation of irrigants
Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced May 22, 2026, 1:34 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Healthy, Inflammation, Mouth Disease, Pain
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced May 22, 2026, 1:34 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Irreversible Pulpitis
Interventions
Ibuprofen, Methylprednisolone
Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced May 22, 2026, 1:34 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pulpitis
Interventions
non-eugenol based ZOE base material with Ferric Sulfate in primary molar pulpotomies, eugenol based zinc oxide and Ferric Sulfate
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
3 Years to 7 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced May 22, 2026, 1:34 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Endodontic Disease, Post Operative Pain, Symptomatic Irreversible Pulpitis
Interventions
Local anesthetic
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced May 22, 2026, 1:34 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Acute Pulpitis
Interventions
Brain wave analysis using electroencephalography (EEG)., Numerical rate Scale (NRS)
Diagnostic Test
Lead sponsor
Cleveland Dental Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced May 22, 2026, 1:34 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Reversible Pulpitis, Dental Pulp Diseases
Interventions
NeoMTA, ProRoot MTA
Biological · Other
Lead sponsor
Texas A & M University Baylor College Of Dentistry
Other
Eligibility
2 Years to 8 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced May 22, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pain
Interventions
Conventional root canal treatment, Ultrasonic, Apical negative pressure, Combined Ultrasonic and negative pressure
Device
Lead sponsor
Cleveland Dental Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced May 22, 2026, 1:34 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Pulpitis - Irreversible, Caries, Head and Neck Cancer
Interventions
Root canal treatment and crown
Procedure
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 26, 2023 · Synced May 22, 2026, 1:34 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Irreversible Pulpitis
Interventions
IANB Articaine, SUP Articaine, SUP Lidocaine
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Irreversible Pulpitis (Toothache)
Interventions
buffered lidocaine, nonbuffered lidocaine
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced May 22, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Root Canal Infection, Endodontic Disease, Endodontic Inflammation, Post-Operative Pain
Interventions
Gentlewave, Standard Endodontic Protocol
Device · Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced May 22, 2026, 1:34 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Symptomatic Irreversible Pulpitis
Interventions
Onset Sodium Bicarbonate Inj., 8.4%, USP Neutralizing Additive Solution, 2% lidocaine with 1:100,000 epinephrine
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced May 22, 2026, 1:34 AM EDT
Recruiting Phase 2 Interventional
View directory record Official record
Conditions
Pain Assessment, Quality of Life (QOL), Analgesic Use
Interventions
Supplemental Postoperative Bupivacaine, Placebo Injection
Drug
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced May 22, 2026, 1:34 AM EDT