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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Gulf War Illness Clear all
Completed No phase listed Observational

Mechanisms of Mitochondrial Defects in Gulf War Syndrome

NCT01264471
View directory record Official record
Conditions
Gulf War Syndrome, Mitochondrial Disease
Interventions
Skin biopsy, Blood Collection
Procedure
Lead sponsor
Medical Neurogenetics, LLC
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2015 · Synced Jul 23, 2026, 7:38 AM EDT
Recruiting Phase 2 Interventional

Study of Bacopa in Gulf War Illness Patients

NCT04927338
View directory record Official record
Conditions
Gulf War Illness
Interventions
BacoMind® (Bacopa monnieri standardized extract), Placebo
Dietary Supplement · Drug
Lead sponsor
Nova Southeastern University
Other
Eligibility
46 Years to 78 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Jul 23, 2026, 7:38 AM EDT
Not listed Phase 2 Interventional

Intranasal Insulin: A Novel Treatment for Gulf War Multisymptom Illness

NCT01802944
View directory record Official record
Conditions
Chronic Multisymptom Illness in Gulf War Veterans
Interventions
Intranasal Insulin, Placebos
Drug
Lead sponsor
Bronx Veterans Medical Research Foundation, Inc
Other
Eligibility
40 Years to 89 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 23, 2026, 7:38 AM EDT
Not listed Phase 1Phase 2 Interventional

Thermal Clinic Treatment in Gulf War Illness

NCT02293291
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Lithium Water
Dietary Supplement
Lead sponsor
American Society Of Thermalism And Climatology Inc
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 22, 2015 · Synced Jul 23, 2026, 7:38 AM EDT
Recruiting Early Phase 1 Interventional

GWICTIC: NAC Mechanistic Study in Gulf War Veterans

NCT04987775
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
N-Acetyl Cysteine, Placebo
Drug
Lead sponsor
Nova Southeastern University
Other
Eligibility
47 Years to 70 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Palo Alto, California • Fort Lauderdale, Florida • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Not applicable Interventional Results available

Scalp Application of LED Therapy to Improve Thinking and Memory in Veterans With Gulf War Illness

NCT01782378
View directory record Official record
Conditions
Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
Interventions
Real LED Treatment, Sham LED Treatment
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
38 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Phase 2 Interventional Results available

Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI)

NCT01956279
View directory record Official record
Conditions
Fatigue, Musculoskeletal Pain, Cognitive Decline
Interventions
Pregnenolone, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 65 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Acupuncture in the Treatment of Gulf War Illness

NCT01305811
View directory record Official record
Conditions
Persian Gulf Syndrome
Interventions
Acupuncture
Device
Lead sponsor
New England School of Acupuncture
Other
Eligibility
39 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2015 · Synced Jul 23, 2026, 7:38 AM EDT
Recruiting Not applicable Interventional

Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome

NCT07151248
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Cranial electrical/electrotherapy stimulation (CES), Sham Cranial electrical/electrotherapy stimulation (CES)
Device
Lead sponsor
Emory University
Other
Eligibility
40 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jul 23, 2026, 7:38 AM EDT
Recruiting Phase 2 Interventional

Resistant Potato Starch to Alleviate GWI

NCT05820893
View directory record Official record
Conditions
Gulf War Illness
Interventions
Resistant Potato Starch
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 7:38 AM EDT
Not listed Phase 2 Interventional

Methylphenidate Plus GWI-Nutrient Formula as a Treatment for Patients With Gulf War Illness

NCT02357030
View directory record Official record
Conditions
Gulf War Illness
Interventions
Methyl-P plus GWI Nutrient Formula
Drug
Lead sponsor
K-PAX Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2015 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Not applicable Interventional

Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI

NCT05377242
View directory record Official record
Conditions
Gulf War Illness
Interventions
Curcumin, Resveratrol, Stinging Nettle
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
45 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Phase 3 Interventional

Exercise and Behavioral Therapy Trial (EBT).

NCT00007748
View directory record Official record
Conditions
Persian Gulf Syndrome
Interventions
Aerobic exercise, Cognitive behavioral therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
1,064 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
28
States / cities
Birmingham, Alabama • San Diego, California • San Francisco, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2015 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Not applicable Interventional

Q10 for Gulf War Veterans

NCT01011348
View directory record Official record
Conditions
Gulf War Illness
Interventions
Coenzyme Q10, Placebo
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Jul 23, 2026, 7:38 AM EDT
Recruiting Phase 1 Interventional

Clinical Evaluation of Montelukast in Veterans With Gulf War Illness

NCT05992311
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Montelukast, Placebo
Drug · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
50 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Phase 2 Interventional Results available

Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)

NCT00810368
View directory record Official record
Conditions
Persian Gulf Syndrome
Interventions
Carnosine, Placebo
Drug
Lead sponsor
Georgetown University
Other
Eligibility
34 Years to 82 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy for Insomnia for Gulf War Illness

NCT02782780
View directory record Official record
Conditions
Gulf War Illness, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBTi)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Not applicable Interventional

Pilot Test of Apnea and Insomnia Relief for Veterans With Gulf War Illness

NCT05137743
View directory record Official record
Conditions
Gulf War Illness
Interventions
Apnea and Insomnia Relief (AIR), Sleep Education (SE)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
48 Years to 80 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Phase 2 Interventional

Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms

NCT01543997
View directory record Official record
Conditions
Sleep Disturbance, Persian Gulf War Syndrome in Veteran
Interventions
Mind-Body Bridging Program, Supportive Education
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
38 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Jul 23, 2026, 7:38 AM EDT
Recruiting Not applicable Interventional

Mechanisms of Gulf War Illness

NCT05972291
View directory record Official record
Conditions
Gulf War Illness, Irritable Bowel Syndrome, Gastrointestinal Symptoms
Interventions
Oral Glutamine, Control Arm
Dietary Supplement · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 23, 2026, 7:38 AM EDT
Not listed Phase 2 Interventional

Multimodal Investigation of the Neuroprotective Effects of Resveratrol (MINER)

NCT03665740
View directory record Official record
Conditions
Gulf War Illness
Interventions
Resveratrol
Drug
Lead sponsor
VISN 17 Center of Excellence
Federal
Eligibility
44 Years to 68 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jul 23, 2026, 7:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

START & STOPP in GWI

NCT03560830
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
2 submaximal exercise stress tests
Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Not applicable Interventional Results available

Novel Interventions for GWVI

NCT02661997
View directory record Official record
Conditions
Gulf War Veteran's Illness
Interventions
Tai Chi Intervention, Wellness Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Jul 23, 2026, 7:38 AM EDT
Completed Phase 2 Interventional Results available

Gulf War Illness Inflammation Reduction Trial

NCT02506192
View directory record Official record
Conditions
Chronic Inflammation, Chronic Pain, Fatigue, Cognitive Impairment
Interventions
Modified-Release Prednisone, Placebo
Drug
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
Not listed
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Jul 23, 2026, 7:38 AM EDT