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ClinicalTrials.gov public records Last synced May 21, 2026, 7:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 2,392 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Heart Failure, Congestive Clear all
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction
Interventions
Synchronized Diaphragmatic Stimulation
Device
Lead sponsor
VisCardia Inc.
Industry
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced May 21, 2026, 7:18 PM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Adult Congenital Heart Disease, Congenital Heart Disease, Systemic Right Ventricle, Transposition of the Great Arteries, Congenitally Corrected Transposition of the Great Arteries, Fontan, Single Ventricle, Tetralogy of Fallot (TOF)
Interventions
SGLT2 inhibitors
Drug
Lead sponsor
Leiden University Medical Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Baltimore, Maryland • Grand Rapids, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Heart Failure
Interventions
Primary Palliative Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
White Oak, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced May 21, 2026, 7:18 PM EDT
Withdrawn Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Heart Failure
Interventions
Teaching for Interactive Patient Self-Management (TIPS) for Heart Failure (HF
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
55 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Charleston, South Carolina • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 1, 2014 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Heart Failure, Dilated Cardiomyopathy
Interventions
PITA
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced May 21, 2026, 7:18 PM EDT
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Hemolysis Intravascular, Acute Decompensated Heart Failure
Interventions
Pentoxifylline Oral Product, Placebo
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced May 21, 2026, 7:18 PM EDT
Recruiting Phase 1 Interventional
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
MTP-101-C encapsulated Microbiota, Vancomycin, Neomycin
Biological · Drug
Lead sponsor
Melana Yuzefpolskaya, MD
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced May 21, 2026, 7:18 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Congestive Heart Failure, Ventricular Function, Left
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 22, 2016 · Synced May 21, 2026, 7:18 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
19 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 4, 2016 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Heart Failure
Interventions
Medically Tailored Meal Program with Traditional Navajo Foods
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tohatchi, New Mexico
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced May 21, 2026, 7:18 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Mental Stress
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Hartford, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions
Dapagliflozin, Placebo
Drug · Other
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 150 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
23
States / cities
Alexander City, Alabama • Fairhope, Alabama • Fort Payne, Alabama + 19 more
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced May 21, 2026, 7:18 PM EDT
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Hypertension
Interventions
Eplerenone, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced May 21, 2026, 7:18 PM EDT
Terminated Phase 4 Interventional
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Beta blocker (carvedilol or metoprolol succinate), CRT (cardiac resynchronization therapy)
Drug · Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 99 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
New York, New York • Rochester, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 29, 2015 · Synced May 21, 2026, 7:18 PM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Heart Failure
Interventions
Usual Care, Exercise Training, Dietary Counseling
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2026
U.S. locations
2
States / cities
Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced May 21, 2026, 7:18 PM EDT
Terminated Phase 2 Interventional
View directory record Official record
Conditions
Diastolic Heart Failure
Interventions
alagebrium, placebo
Drug
Lead sponsor
Synvista Therapeutics, Inc
Industry
Eligibility
50 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
30
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 27 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2009 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Heart Failure
Interventions
Automated Medication Dispensing Device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2015 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Heart Failure, Left Bundle-Branch Block
Interventions
Mapping and Pacing the His Bundle, Placing a guidewire in Coronary sinus for measurement of Q-LV during His Bundle pacing or, if needed, for LV pacing
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced May 21, 2026, 7:18 PM EDT
Terminated Phase 2 Interventional Results available
View directory record Official record
Conditions
Heart Failure, Heart Failure With Preserved Ejection Fraction
Interventions
LY3540378, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
22
States / cities
Tucson, Arizona • Covina, California • Northridge, California + 18 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Advanced Refractory Left Ventricular Heart Failure
Interventions
HeartMate 3 LVAS
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 100 Years
Enrollment
1,685 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
69
States / cities
Little Rock, Arkansas • Beverly Hills, California • La Jolla, California + 53 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced May 21, 2026, 7:18 PM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Heart Failure, Transplant; Failure, Heart
Interventions
Non-Ischemic Heart Preservation (NIHP) using the XVIVO Heart Preservation System (XHPS)
Device
Lead sponsor
XVIVO Perfusion
Industry
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
20
States / cities
La Jolla, California • Los Angeles, California • Palo Alto, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Heart Failure With Normal Ejection Fraction
Interventions
Anakinra, Placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced May 21, 2026, 7:18 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
CMR/CTA Guidance for CRT
Diagnostic Test
Lead sponsor
University of Virginia
Other
Eligibility
20 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Left Ventricular Insufficiency
Interventions
CD-NP, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced May 21, 2026, 7:18 PM EDT