A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)
Public ClinicalTrials.gov record NCT05592275. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of LY3540378 in Adults With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to assess the efficacy and safety of LY3540378 in adults with worsening heart failure with preserved ejection fraction
Study identification
- NCT ID
- NCT05592275
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 332 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 3, 2023 (Actual)
- Primary completion
- Jan 22, 2025 (Actual)
- Completion
- Jan 22, 2025 (Actual)
- Last update posted
- Feb 5, 2026
2023 – 2025
United States locations
- U.S. sites
- 22
- U.S. states
- 11
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pima Heart | Tucson | Arizona | 85719 | — |
| Valley Clinical Trials, Inc. | Covina | California | 91723 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| University of California Irvine Medical Center | Orange | California | 92868 | — |
| Pasadena Clinical Research | Pasadena | California | 91105 | — |
| Velocity Clinical Research, Coastal Heart Medical Group | Santa Ana | California | 92704 | — |
| Excel Medical Clinical Trials | Boca Raton | Florida | 33434 | — |
| Infinite Clinical Research | Miami | Florida | 33133 | — |
| South Florida Research Solutions - North Flamingo Road | Pembroke Pines | Florida | 33028 | — |
| University Medical Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Mayo Clinic in Rochester, Minnesota | Rochester | Minnesota | 55905 | — |
| University of North Carolina Medical Center | Chapel Hill | North Carolina | 27514 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| PharmaTex Research | Amarillo | Texas | 79109 | — |
| Baylor Scott & White Health-Advanced Heart and Lung Disease | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0553 | — |
| West Houston Area Clinical Trial Consultants | Houston | Texas | 77094 | — |
| Texas Institute of Cardiology, PA | McKinney | Texas | 75071 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 115 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05592275, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 5, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05592275 live on ClinicalTrials.gov.