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ClinicalTrials.gov public records Last synced Oct 29, 2026, 10:56 PM EDT

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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hernia, Inguinal Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prospective Trial Comparing Two Different Polypropylene Meshes for Inguinal Hernias

NCT01825187
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
ULTRAPRO Mesh, 3DMAX, Evaluation
Device · Other
Lead sponsor
South East Area Health Education Center, Wilmington, NC
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Oct 29, 2026, 10:56 PM EDT
Completed No phase listed Observational

Pain and Quality of Life After Inguinal Hernia Repair

NCT04074200
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Open Inguinal Hernia Repair, Laparoscopic Inguinal Hernia Repair, Robotic-Assisted Inguinal Hernia Repair
Procedure · Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years to 80 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 29, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair

NCT05484635
View directory record Official record
Conditions
Chronic Groin Pain, Hernia, Inguinal
Interventions
Diagnostic laparoscopy and inguinal mesh removal, Diagnostic laparoscopy
Procedure
Lead sponsor
David Krpata
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 29, 2026, 10:56 PM EDT
Completed No phase listed Observational

Quantitative Sensory Testing and Analysis of Post Inguinal Hernia Surgery Pain

NCT01534429
View directory record Official record
Conditions
Hernia
Interventions
Quantitative Sensory Testing
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2016 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of CollaRx® Bupivacaine Implant in Men After Open Laparotomy Herniorrhaphy

NCT01220024
View directory record Official record
Conditions
Herniorrhaphy, Postoperative Pain, Inguinal Hernia
Interventions
Bupivacaine Collagen Sponge, Placebo collagen Sponge
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Phase 4 Interventional Results available

Awake Caudal Catheter vs General Anesthesia

NCT05919732
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
23 Weeks to 60 Weeks
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Phase 3 Interventional Results available

The POUR (Postoperative Urinary Retention) Study

NCT05276804
View directory record Official record
Conditions
Postoperative Urinary Retention
Interventions
Sugammadex
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Watchful Waiting Versus Open Tension-free Repair of Inguinal Hernia in Asymptomatic or Minimally Symptomatic Men

NCT00263250
View directory record Official record
Conditions
Inguinal Hernia
Interventions
watchful waiting or tension-free hernia repair
Procedure
Lead sponsor
Creighton University
Other
Eligibility
18 Years and older · Male only
Enrollment
724 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Oct 29, 2026, 10:56 PM EDT
Not listed No phase listed Observational

Use of Parietex Plug and Patch Hernia System in Open Inguinal Hernia Repair

NCT01590940
View directory record Official record
Conditions
Evaluate the Use of a New Mesh Type in Open Inguinal Hernia Repair
Interventions
Open inguinal hernia repair with mesh
Procedure
Lead sponsor
Owen Drive Surgical Clinic of Fayetteville
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Fayetteville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2012 · Synced Oct 29, 2026, 10:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bassini Inguinal Hernia Repair: Obsolete Or Still A Viable Surgical Option?

NCT04888078
View directory record Official record
Conditions
Inguinal Hernia, Surgery--Complications, Surgical Complication
Interventions
Bassini hernia repair
Procedure
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Phase 3 Interventional

Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients?

NCT00032448
View directory record Official record
Conditions
Hernia
Interventions
Standardized tension-free herniorrhaphy with prosthesis
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Male only
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
14
States / cities
Birmingham, Alabama • No. Little Rock, Arkansas • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2011 · Synced Oct 29, 2026, 10:56 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Comparison of Patient Perceived Pain and Satisfaction Between Lightweight and Heavyweight Mesh for Laparoscopic Inguinal Hernia Repair

NCT01638221
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Not listed
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Oct 29, 2026, 10:56 PM EDT
Not listed No phase listed Observational

Early Surgeon Experience With Robotic-Assisted Inguinal Hernia Repair

NCT04353687
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
Robotic-assisted inguinal hernia repair
Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Newport News, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 29, 2026, 10:56 PM EDT
Recruiting Phase 4 Interventional

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

NCT05722002
View directory record Official record
Conditions
Surgery, Pain, Postoperative
Interventions
NSAID, Opioid, Acetaminophen
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
6
States / cities
Ann Arbor, Michigan • Detroit, Michigan • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 29, 2026, 10:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Analgesia in Children Using Caudal Epidural Ropivacaine

NCT01494272
View directory record Official record
Conditions
Inguinal Hernia, Circumcision
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
2 Months to 2 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Phase 4 Interventional

Extended Delivery of Bupivacaine Study in Herniorrhaphy

NCT04102267
View directory record Official record
Conditions
Analgesia
Interventions
Bupivacaine liposome injectable suspension, Bupivacaine HCl without epinephrine via continuous infusion
Drug
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 29, 2026, 10:56 PM EDT
Not listed Phase 3 Interventional

Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair

NCT03262688
View directory record Official record
Conditions
Inguinal Hernia, Postoperative Pain
Interventions
Bupivacaine HCl collagen-matrix implant, Bupivacaine HCl infiltration
Drug
Lead sponsor
Innocoll
Industry
Eligibility
2 Years to 16 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
11
States / cities
Laguna Hills, California • Altamonte Springs, Florida • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2021 · Synced Oct 29, 2026, 10:56 PM EDT
Completed No phase listed Observational

A Prospective Study to Compare the Clinical Outcomes, Pain and Patient Quality of Life for Hernia Patients

NCT02715622
View directory record Official record
Conditions
Hernia, Incisional Hernia, Hernia, Inguinal, Indirect, Hernia, Inguinal, Direct, Inguinal Hernia
Interventions
Hernia repair
Procedure
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years and older
Enrollment
944 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
17
States / cities
Beverly Hills, California • Nashville, California • Oakland, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 29, 2026, 10:56 PM EDT
Recruiting Phase 1 Interventional

Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males

NCT07604272
View directory record Official record
Conditions
Inguinal Hernia Unilateral, Inguinal Hernia Bilateral, Inguinal Hernia Without Obstruction or Gangrene, Inguinal Hernia, Without Mention of Obstruction or Gangrene
Interventions
Fulvestrant, Anastrozole (ARIMIDEX™)
Drug
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 29, 2026, 10:56 PM EDT
Terminated Phase 2Phase 3 Interventional

Post-Operative Pain Scores and Analgesic Requirements After Elective Inguinal Herniorrhaphy

NCT00735124
View directory record Official record
Conditions
Pain, Analgesia, Hernia, Inguinal
Interventions
Gabapentin, placebo
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 28, 2017 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Biomechanically Compatible,Minimally Invasive Technique for Recurrence Free Groin Hernia Repair

NCT04764760
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Wing shaped Tensiflex prosthesis
Device
Lead sponsor
St. Joseph Mercy Oakland Hospital
Other
Eligibility
20 Years to 80 Years
Enrollment
486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1987 – 2001
U.S. locations
1
States / cities
Pontiac, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Inguinal Hernia Management: Watchful Waiting vs. Tension-Free Open Repair

NCT01922674
View directory record Official record
Conditions
Inguinal Hernias
Interventions
Standard open tension-free inguinal hernia repair with mesh
Procedure
Lead sponsor
Creighton University
Other
Eligibility
18 Years and older · Male only
Enrollment
720 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Oct 29, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Timing of Inguinal Hernia Repair in Premature Infants

NCT01678638
View directory record Official record
Conditions
Inguinal Hernia, Premature Birth of Newborn
Interventions
IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 37 Weeks
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
40
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 33 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 29, 2026, 10:56 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain

NCT05386693
View directory record Official record
Conditions
Hernia, Inguinal, Chronic Postoperative Pain
Interventions
Ilioinguinal nerve block
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 29, 2026, 10:56 PM EDT