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ClinicalTrials.gov public records Last synced May 22, 2026, 3:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Hopelessness Clear all
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pulpitis, Dental Pulp Diseases, Tooth Diseases
Interventions
Pulpotomy, Extraction and placement of space maintainer
Procedure
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 10 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced May 22, 2026, 3:43 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Duloxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002
U.S. locations
9
States / cities
Trumbull, Connecticut • Lafayette, Indiana • Gaithersburg, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2006 · Synced May 22, 2026, 3:43 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Suicidal Ideation, Hopelessness, Wish to Live, Wish to Die
Interventions
Single-Session Mechanism-Focused Intervention (SSMFI), Distress Tolerance Skills Review
Behavioral
Lead sponsor
Shannon E. Sauer-Zavala
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced May 22, 2026, 3:43 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
duloxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
23
States / cities
Carlsbad, California • Los Angeles, California • Stanford, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2006 · Synced May 22, 2026, 3:43 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Suicide
Interventions
Robinson's Culturally Adapted Coping with Stress Course (A-CWS), Standard Care Control Condition
Behavioral
Lead sponsor
DePaul University
Other
Eligibility
12 Years and older
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
6
States / cities
Chicago, Illinois • Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced May 22, 2026, 3:43 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Suicidal Behavior, Depression / Major Depressive Disorder, Hopelessness, Neurobiological
Interventions
CAMS
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
14 Years to 24 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced May 22, 2026, 3:43 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymia, Depression Not Otherwise Specified, Borderline Personality Disorder
Interventions
Lithium Carbonate, Placebo, Citalopram
Drug
Lead sponsor
Columbia Northwest Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
San Diego, California • Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Aug 23, 2011 · Synced May 22, 2026, 3:43 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Ischemic Heart Disease, Hopelessness, Physical Activity, Motivation, Social Support, Covid19
Interventions
Motivational social support from nurse, Motivational social support from nurse with additional support from significant other, Attention control
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced May 22, 2026, 3:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
Interventions
0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced May 22, 2026, 3:43 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2014 · Synced May 22, 2026, 3:43 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Cardiac Disease, Mental Health Issue
Interventions
Rurality; Ethnicity; Exercise; Hopelessness
Other
Lead sponsor
Dordt University
Other
Eligibility
Not listed
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced May 22, 2026, 3:43 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Ischemic Heart Disease
Interventions
Not listed
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced May 22, 2026, 3:43 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Traumatic Brain Injury, Hopelessness, Suicide
Interventions
Window to Hope, Waitlist Control
Other
Lead sponsor
Lisa Brenner
Federal
Eligibility
18 Years to 89 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced May 22, 2026, 3:43 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Advanced Cancer
Interventions
questionnaires
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2009 · Synced May 22, 2026, 3:43 AM EDT