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ClinicalTrials.gov public records Last synced May 22, 2026, 12:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hypotonia Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Muscle Relaxants
Interventions
Succinylcholine
Drug
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 1, 2018 · Synced May 22, 2026, 12:09 AM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 23 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced May 22, 2026, 12:09 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Focal Dystonia
Interventions
Botulinum toxin, type B
Drug
Lead sponsor
Columbia University
Other
Eligibility
25 Years to 69 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced May 22, 2026, 12:09 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Target Drug-related Adverse Events
Interventions
Urine diagnostic testing as SOC, drug regimen changes per SOC, Urine diagnostic testing with selective PGx testing, drug regimen changes based on PGx test results
Other
Lead sponsor
InSource Diagnostics
Industry
Eligibility
12 Years and older
Enrollment
14,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
Tazewell, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced May 22, 2026, 12:09 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Thymidine Kinase 2 (TK2)
Interventions
dC/dT
Drug
Lead sponsor
Zogenix MDS, Inc.
Industry
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced May 22, 2026, 12:09 AM EDT
Withdrawn No phase listed Observational
View directory record Official record
Conditions
Muscle Relaxants
Interventions
Not listed
Lead sponsor
Shashi Bhatt, MD
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 18, 2016 · Synced May 22, 2026, 12:09 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Cardiovascular Surgery, Bispectral Index, Anesthesia
Interventions
Bispectral Index (BIS) monitoring system
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced May 22, 2026, 12:09 AM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Neurofibromatosis Type 1
Interventions
Magnetic resonance imaging, Gadolinium contrast
Device · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Year to 7 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 2, 2019 · Synced May 22, 2026, 12:09 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Myotubular Myopathy
Interventions
Not listed
Lead sponsor
Valerion Therapeutics, LLC
Industry
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced May 22, 2026, 12:09 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Surgery
Interventions
Neostigmine+glycopyrrolate, Sugammadex
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
4
States / cities
Basking Ridge, New Jersey • Commack, New York • Harrison, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced May 22, 2026, 12:09 AM EDT
Active, not recruiting Phase 2 Interventional Results available
View directory record Official record
Conditions
Prostate Cancer
Interventions
Rocuronium 0.3mg/kg/hr, Rocuronium 1.5mg/kg/hr
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced May 22, 2026, 12:09 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Muscle Relaxation, Sex
Interventions
Mivacurium
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2014 · Synced May 22, 2026, 12:09 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypertonia, Muscle, Nasal Airway Obstruction, Tolerance, Trisomy 21, Down Syndrome
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 21 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced May 22, 2026, 12:09 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Hypotonia, Child, Only
Interventions
ssNPA
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 21 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced May 22, 2026, 12:09 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Neurodevelopmental Disorders, Intellectual Disability, Developmental Delay, Autism Spectrum Disorder, Seizures, Hypertonia, Muscle, Hypotonia
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced May 22, 2026, 12:09 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Epilepsy; Seizure, Neuromuscular Diseases, Brain Malformation, Intellectual Disability, Autism Spectrum Disorder, Hypotonia, Inborn Errors of Metabolism, Movement Disorders, Genetic Disease, Development Delay, Chromosome Abnormality, Hearing Loss, Dysmorphic Features, Skeletal Dysplasia, Congenital Abnormality, Microcephaly, Macrocephaly
Interventions
Pre-visit prep, usual care + exome seq
Behavioral · Diagnostic Test
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
0 Years and older
Enrollment
548 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
3
States / cities
Asheville, North Carolina • Chapel Hill, North Carolina • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced May 22, 2026, 12:09 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Cerebral Palsy
Interventions
SPIO® Core-MAX® Expedition thoracolumbosacral orthosis, Standard Care Therapy option
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
6 Months to 18 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced May 22, 2026, 12:09 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Congenital Disorders of Glycosylation
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
1 Month to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced May 22, 2026, 12:09 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Propionic Acidemia
Interventions
ornithine alpha ketoglutarate, glutamine, disodium citrate
Drug
Lead sponsor
Nicola Longo
Other
Eligibility
5 Years to 12 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 20, 2015 · Synced May 22, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Flaccid Muscle Tone
Interventions
muscle biopsy
Procedure
Lead sponsor
Purdue University
Other
Eligibility
20 Years to 29 Years · Male only
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced May 22, 2026, 12:09 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Cerebral Palsy, Traumatic Brain Injury, Metabolic Disease, Hypotonia
Interventions
customized posture support
Device
Lead sponsor
University of Hartford
Other
Eligibility
3 Months to 21 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
3
States / cities
Cheshire, Connecticut • Hartford, Connecticut • Wethersfield, Connecticut
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced May 22, 2026, 12:09 AM EDT