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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ileus Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects

NCT00311350
View directory record Official record
Conditions
Postoperative Complications, Constipation
Interventions
MOA-728
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2019 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Not applicable Interventional Results available

Optimizing the Previs Device for Prediction of Postoperative Ileus

NCT03505476
View directory record Official record
Conditions
Ileus
Interventions
Entac Medical device application, Patient Daily Assessment, Patient Discharge Assessment
Device · Other
Lead sponsor
Jennifer Hrabe
Other
Eligibility
18 Years to 100 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 12, 2025 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 3 Interventional Results available

Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

NCT01553747
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Eluxadoline, Placebo
Drug
Lead sponsor
Furiex Pharmaceuticals, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
232
States / cities
Birmingham, Alabama • Decatur, Alabama • Huntsville, Alabama + 189 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2018 · Synced Sep 9, 2026, 5:50 PM EDT
Completed No phase listed Observational

Measurement of Body Composition by Air Displacement Plethysmography in Pediatric Intestinal Failure Patients

NCT02561819
View directory record Official record
Conditions
Short Bowel Syndrome
Interventions
Not listed
Lead sponsor
Christopher Duggan
Other
Eligibility
2 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 2 Interventional

Trial of Acupuncture for Reduction of Post-Colectomy Ileus

NCT00402961
View directory record Official record
Conditions
Postoperative Ileus, Colon Cancer, Pain, Postoperative, Postoperative Nausea and Vomiting
Interventions
Acupuncture, Sham Acupuncture
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2015 · Synced Sep 9, 2026, 5:50 PM EDT
Terminated Phase 3 Interventional Results available

A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection

NCT05470387
View directory record Official record
Conditions
Ileus, Gastro-Intestinal Disorder
Interventions
LB1148, Placebo
Drug
Lead sponsor
Palisade Bio
Industry
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
23
States / cities
Mobile, Alabama • La Jolla, California • Orange, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Not applicable Interventional Results available

Alvimopan and Ileus in PSF

NCT02218190
View directory record Official record
Conditions
Ileus, Spinal Fusion
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 16, 2019 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Not applicable Interventional

Prevention of Ileus After Gynecologic Surgery Using Chewing Gum

NCT00831246
View directory record Official record
Conditions
Ileus
Interventions
chewing gum - Extra Winterfresh, Standard Post-Op Care
Other
Lead sponsor
Aultman Health Foundation
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Canton, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Sep 9, 2026, 5:50 PM EDT
Terminated Phase 2 Interventional Results available

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC

NCT03352414
View directory record Official record
Conditions
Ileus
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Sep 9, 2026, 5:50 PM EDT
Not listed Phase 4 Interventional

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

NCT02958566
View directory record Official record
Conditions
Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis, Pain, Postoperative, Ileus, Ileus Paralytic, Ileus; Mechanical, Constipation Drug Induced, Constipation, Rectum Cancer, Rectum Neoplasm
Interventions
Acetaminophen, Gabapentin, Orphenadrine, Lidocaine, Marcaine, Ketamine, Methadone, Tramadol, Ketorolac, Morphine Sulfate, Fentanyl, Dilaudid, Hydrocodone-Acetaminophen Tab 5-325 MG, HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
Drug
Lead sponsor
University of Illinois College of Medicine at Peoria
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 19, 2017 · Synced Sep 9, 2026, 5:50 PM EDT
Not listed Not applicable Interventional

Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment

NCT04880473
View directory record Official record
Conditions
Gastrointestinal Complication
Interventions
PrevisEA device
Device
Lead sponsor
Entac Medical Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
8
States / cities
Orlando, Florida • Chicago, Illinois • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of TU-100 on Gastrointestinal and Colonic Transit in Humans

NCT00871325
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Daikenchuto (TU-100), Placebo
Drug
Lead sponsor
Tsumura USA
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 13, 2013 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection

NCT02836470
View directory record Official record
Conditions
Ileus, Post-Operative Adhesions
Interventions
LB1148, Placebo
Drug
Lead sponsor
Palisade Bio
Industry
Eligibility
18 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
28
States / cities
Mobile, Alabama • Yuma, Arizona • Irvine, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Not applicable Interventional

Acupuncture and Post-Operative Ileus

NCT00655317
View directory record Official record
Conditions
Ileus
Interventions
Acupuncture, Sham acupuncture
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2011 · Synced Sep 9, 2026, 5:50 PM EDT
Not listed Phase 4 Interventional

Neostigmine Route for Acute Colonic Pseudo Obstruction

NCT04951726
View directory record Official record
Conditions
Ogilvie Syndrome
Interventions
Neostigmine
Drug
Lead sponsor
University of Southern California
Other
Eligibility
16 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 3 Interventional

Does Coffee Consumption Prevent or Shorten Postoperative Ileus After Colon Resection?

NCT01130675
View directory record Official record
Conditions
Postoperative Ileus
Interventions
caffeinated coffee
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 10, 2013 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 1 Interventional

A Study to Evaluate the Safety, Tolerability and Efficacy of LB1148 for Subjects Undergoing Elective Bowel Resection

NCT04100447
View directory record Official record
Conditions
Adhesions, Ileus
Interventions
Tranexamic Acid
Drug
Lead sponsor
Ronald Hurst, MD, FACS
Other
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Inglewood, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Sep 9, 2026, 5:50 PM EDT
Not listed No phase listed Observational

G-Tech Feasibility Study for Early Detection of a Post-op Ileus

NCT02673671
View directory record Official record
Conditions
Post-operative Ileus
Interventions
G-Tech Myoelectric recording device
Device
Lead sponsor
G-Tech Corporation
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2023 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 4 Interventional Results available

A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy

NCT00708201
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
20
States / cities
Laguna Hills, California • Aurora, Colorado • Miami, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Sep 9, 2026, 5:50 PM EDT
Withdrawn Not applicable Interventional

Neurostimulation for the Treatment of Post-Operative Ileus

NCT00854074
View directory record Official record
Conditions
Ileus
Interventions
ElectroCore RMS-1100 Resolution Motility System™
Device
Lead sponsor
ElectroCore INC
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
3
States / cities
Chicago, Illinois • Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Sep 9, 2026, 5:50 PM EDT
Not listed Not applicable Interventional

Use of Pedometer Following Radical Cystectomy

NCT04305730
View directory record Official record
Conditions
Bladder Cancer, Ileus, Narcotic Use
Interventions
Use of a pedometer following surgery, Standard of care
Behavioral
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 1 Interventional

Therapeutic Oxygen for Gastrointestinal Atony (TOGA)

NCT03386136
View directory record Official record
Conditions
Ileus, Ogilvie Syndrome, Small Bowel Obstruction
Interventions
100% Oxygen
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Not applicable Interventional

The Effect of Coffee After Resection of Small Bowel

NCT03143621
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Coffee, Water
Dietary Supplement · Other
Lead sponsor
Mount Carmel Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Sep 9, 2026, 5:50 PM EDT
Completed Phase 2 Interventional

Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery

NCT00617552
View directory record Official record
Conditions
Postoperative Ileus
Interventions
5% dextrose in water, TZP-101
Drug
Lead sponsor
Tranzyme, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
10
States / cities
Los Angeles, California • Miami, Florida • Ocala, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2012 · Synced Sep 9, 2026, 5:50 PM EDT