Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery

ClinicalTrials.gov ID: NCT00617552

Public ClinicalTrials.gov record NCT00617552. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 21, 2026, 6:42 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Assess Efficacy and Safety of TZP-101 When Administered as 30 Minute i.v. Infusion for POI to Subjects Undergoing Major Open Abdominal Surgery

Study identification

NCT ID: NCT00617552
Recruitment status: Completed
Study type: Interventional
Phase: Phase 2
Lead sponsor: Tranzyme, Inc.; Industry
Enrollment: 267 participants

Conditions and interventions

Conditions

Postoperative Ileus

Interventions

5% dextrose in water Drug
TZP-101 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 30, 2007
Primary completion: Jun 30, 2008
Completion: Jul 31, 2008
Last update posted: Dec 6, 2012

2007 – 2008

United States locations

U.S. sites: 10
U.S. states: 9
U.S. cities: 10

Facility	City	State	ZIP	Site status
Office of Dr. Phillip Fleshner	Los Angeles	California	90048	—
University of Miami Clinic	Miami	Florida	33136	—
Renstar Medical Research	Ocala	Florida	34471	—
Northwestern University	Chicago	Illinois	60611	—
Univ. of Maryland, R.A. Cowley Shock Trauma Center	Baltimore	Maryland	21201	—
Baystate Medical Center/Baystate Health	Springfield	Massachusetts	01199	—
Michigan State/Spectrum Health	Grand Rapids	Michigan	49503	—
Stony Brook University Hospital	Stony Brook	New York	11794	—
Mid Dakota Clinic, PC	Bismarck	North Dakota	58501	—
The Methodist Hospital	Houston	Texas	77030	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT00617552, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Dec 6, 2012 · Synced Jul 21, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00617552 live on ClinicalTrials.gov.

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