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ClinicalTrials.gov public records Last synced Sep 27, 2026, 2:13 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: In-Hospital Cardiac Arrest Clear all
Not yet recruiting Phase 2 Interventional

Naloxone for Opioid Associated Out of Hospital Cardiac Arrest

NCT06251609
View directory record Official record
Conditions
Heart Arrest, Out-Of-Hospital, Opioid Overdose, Naloxone
Interventions
Naloxone 2 MG, Saline 2ml
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Induction of Mild Hypothermia Following Out-of-hospital Cardiac Arrest

NCT00391469
View directory record Official record
Conditions
Out-of-hospital Cardiac Arrest
Interventions
Rapid infusion of 2 liters of 4oC normal saline, Rapid infusion of cold normal saline
Other · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 1, 2014 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Phase 2 Interventional

Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients

NCT00879892
View directory record Official record
Conditions
Ischemic Brain Injury
Interventions
xenon, Hypothermia
Drug · Other
Lead sponsor
Turku University Hospital
Government
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 27, 2026, 2:13 PM EDT
Completed No phase listed Observational

Quantitative Measurement of Cardiopulmonary Resuscitation (CPR) During In Hospital Cardiac Arrest

NCT00628693
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Resuscitation
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2016 · Synced Sep 27, 2026, 2:13 PM EDT
Terminated Not applicable Interventional Results available

ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest

NCT03119571
View directory record Official record
Conditions
Cardiac Arrest Due to Underlying Cardiac Condition, Ventricular Fibrillation, Cardiopulmonary Arrest With Successful Resuscitation
Interventions
Initial CCL admission, Initial ICU admission
Procedure · Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
21
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Ann Arbor, Michigan + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 27, 2026, 2:13 PM EDT
Recruiting Phase 2Phase 3 Interventional

Surviving PEA in Roanoke (SPEAR) Study

NCT05283850
View directory record Official record
Conditions
Cardiac Arrest, Pulseless Electrical Activity
Interventions
High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy
Drug
Lead sponsor
Carol Bernier
Other
Eligibility
18 Years and older
Enrollment
342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Study the Feasibility and Acceptability of an App to Support Pediatric Resuscitation

NCT06768099
View directory record Official record
Conditions
Pediatric Emergency Medicine, Resuscitation, Pediatrics, Emergency Medical Services, Arrest Cardio Respiratory
Interventions
Linear Cognitive Aid
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Phase 3 Interventional Results available

Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial

NCT00878644
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Therapeutic Hypothermia, Therapeutic Normothermia
Procedure · Other
Lead sponsor
University of Michigan
Other
Eligibility
48 Hours to 18 Years
Enrollment
295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
33
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2017 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest

NCT01509040
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration
Other · Device
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Sep 27, 2026, 2:13 PM EDT
Suspended Phase 1 Interventional

Packed Red Blood Cell Transfusion During Cardiac Arrest

NCT06462027
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Packed Red Blood Cells (1 unit), Packed Red Blood Cells (2 units), Saline
Drug · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 27, 2026, 2:13 PM EDT
Terminated Phase 2Phase 3 Interventional

Assessing CPR Quality During In-Hospital Cardiac Arrest

NCT00228293
View directory record Official record
Conditions
Cardiac Arrest
Interventions
investigational monitor/defibrillator with CPR feedback
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 22, 2013 · Synced Sep 27, 2026, 2:13 PM EDT
Active, not recruiting Not applicable Interventional

The PulsePoint Study

NCT04806958
View directory record Official record
Conditions
Out-Of-Hospital Cardiac Arrest, Heart Arrest, Heart Diseases, Cardiovascular Diseases
Interventions
PulsePoint notification
Other
Lead sponsor
Dr. Steven Brooks
Other
Eligibility
Not listed
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Not applicable Interventional Results available

Pragmatic Airway Resuscitation Trial

NCT02419573
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Endotracheal Intubation, Laryngeal Tube (King)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
3,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
6
States / cities
Birmingham, Alabama • Portland, Oregon • Pittsburgh, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2019 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Phase 4 Interventional Results available

Continuous Chest Compressions vs AHA Standard CPR of 30:2

NCT01372748
View directory record Official record
Conditions
Out of Hospital Cardiac Arrest
Interventions
Standard CPR, Continuous chest compressions
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
23,711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
5
States / cities
Birmingham, Alabama • Pittsburgh, Pennsylvania • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2016 · Synced Sep 27, 2026, 2:13 PM EDT
Withdrawn Early Phase 1 Interventional

Patient Acuity Rating: a Tool to Prevent In-Hospital Cardiac Arrest

NCT01082991
View directory record Official record
Conditions
Heart Arrest
Interventions
Preemptive Rapid Response Team intervention
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2016 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Not applicable Interventional Results available

Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest

NCT01325870
View directory record Official record
Conditions
Cardiac Arrest, Sudden Cardiac Death
Interventions
ACD-CPR, ITPR, S-CPR, Impedance Threshold Device (ITD)
Device · Procedure
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 11, 2016 · Synced Sep 27, 2026, 2:13 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Gathering Evidence on Best Practices for Lay Rescuer CPR Training

NCT05908500
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital
Interventions
CPR Training, CPR Manikin Type
Behavioral · Device
Lead sponsor
University of Nevada, Reno
Other
Eligibility
Not listed
Enrollment
2,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 27, 2026, 2:13 PM EDT
Active, not recruiting Not applicable Interventional

AED 3 Post-Approval Study

NCT05013333
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital
Interventions
AED 3 with Uni-padz
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
2
States / cities
Buffalo, New York • Latham, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Sep 27, 2026, 2:13 PM EDT
Terminated Not applicable Interventional Results available

ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest

NCT00189423
View directory record Official record
Conditions
Heart Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, Cardiac Arrest
Interventions
Use of an impedance threshold device (ITD) during the performance of active compression decompression CPR (ACD-CPR), Standard cardiopulmonary resuscitation (S-CPR)
Device · Procedure
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
1,653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
7
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Royal Oak, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 27, 2026, 2:13 PM EDT
Enrolling by invitation Not applicable Interventional

Increasing Law Enforcement Application of Automated External Defibrillators (AED)s for Cardiac Arrest

NCT07649616
View directory record Official record
Conditions
Heart Arrest, Out-Of-Hospital, Defibrillators
Interventions
AED training adjunct
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

An In-Hospital Family Member Cardiopulmonary Resuscitation (CPR) Education Program

NCT01260441
View directory record Official record
Conditions
Cardiac Arrest, Coronary Disease, Cardiovascular Risk Factors
Interventions
CPR Training using the Family and Friends CPR Anytime VSI Kit
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Sep 27, 2026, 2:13 PM EDT
Suspended Not applicable Interventional

Pediatric Prehospital Airway Resuscitation Trial

NCT06364280
View directory record Official record
Conditions
Heart Arrest, Out-Of-Hospital, Wounds and Injuries, Respiratory Insufficiency in Children, Child, Only, Critical Illness
Interventions
BVM, SGA, ETI
Device
Lead sponsor
Ohio State University
Other
Eligibility
24 Hours to 17 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
10
States / cities
Tucson, Arizona • Los Angeles, California • Sacramento, California + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 27, 2026, 2:13 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest

NCT03452917
View directory record Official record
Conditions
Out-Of-Hospital Cardiac Arrest
Interventions
Placebo, sodium nitrite 45 mg, sodium nitrite 60 mg
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Sep 27, 2026, 2:13 PM EDT
Not listed No phase listed Observational

Save Hearts in Arizona Registry and Education (SHARE) Project

NCT01999036
View directory record Official record
Conditions
Out-of-hospital Cardiac Arrest
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
Not listed
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2020
U.S. locations
1
States / cities
Multiple Locations, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2018 · Synced Sep 27, 2026, 2:13 PM EDT