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ClinicalTrials.gov public records Last synced Sep 23, 2026, 8:19 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intensive Care Unit ICU Clear all
Active, not recruiting Not applicable Interventional

PROSpect: Prone and Oscillation Pediatric Clinical Trial

NCT03896763
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome in Children
Interventions
Either supine or prone positioning and either CMV or HFOV
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
2 Weeks to 20 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
28
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 24 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Phase 4 Interventional

Real-Time Myocardial Perfusion Echocardiography in the ICU

NCT03173716
View directory record Official record
Conditions
Myocardial Perfusion Imaging
Interventions
Definity
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 8, 2020 · Synced Sep 23, 2026, 8:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients

NCT07649876
View directory record Official record
Conditions
Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients, Agitation Associated With Critical Illness, Anxiety Acute
Interventions
Virtual reality (VR) therapy
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 23, 2026, 8:19 PM EDT
Completed No phase listed Observational

Characteristics and Outcomes of Intensive Care Unit Patients Admitted With Novel H1N1 Influenza or Seasonal Influenza

NCT01011582
View directory record Official record
Conditions
H1N1 Influenza, Seasonal Influenza
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2013 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Phase 1 Interventional

Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status Asthmaticus

NCT02872597
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Ipratropium, 0.9% Sodium Chloride, Albuterol, corticosteroids
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
2 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 23, 2026, 8:19 PM EDT
Recruiting Not applicable Interventional

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

NCT04737200
View directory record Official record
Conditions
Feeding Patterns, Sleep, Glucose Intolerance
Interventions
Time-of-day of enteral nutrition provision (daytime first), Time-of-day of enteral nutrition provision (nighttime first)
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 23, 2026, 8:19 PM EDT
Terminated No phase listed Observational

Pilot Study for Verifying Endotracheal Tube Repositioning Using Ultrasound

NCT02407158
View directory record Official record
Conditions
Endotracheal Tube Position
Interventions
SonarMed Airwave Device
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 10, 2018 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Neuroendocrine Mechanisms of Developmental Massage Therapy (DMT) in Preterm Infants: Clinical Study

NCT00722943
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Developmental Massage Therapy, no intervention
Other
Lead sponsor
University of Utah
Other
Eligibility
Up to 14 Days
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 7, 2013 · Synced Sep 23, 2026, 8:19 PM EDT
Completed No phase listed Observational

Identification of Dominate Stressors in the Intensive Care Unit (ICU)

NCT00645008
View directory record Official record
Conditions
Cardiac Surgery Intensive Care Treatment
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 23, 2026, 8:19 PM EDT
Completed No phase listed Observational

Actigraphy to MEasuRe Intensive Care Unit Activity

NCT02263716
View directory record Official record
Conditions
Disability, Physical Activity, Aging, Critical Illness
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Reducing Isolation and Feeling of Loneliness During Critical Illness

NCT05537311
View directory record Official record
Conditions
Critical Illness, Social Isolation, Anxiety, Depression, Post Intensive Care Unit Syndrome
Interventions
Social Engagement
Behavioral
Lead sponsor
Kirby Mayer
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Results available

Very Low Birth Weight Preterm Infant Bundled Care in the NICU

NCT03370757
View directory record Official record
Conditions
Preterm Infants
Interventions
3-hour bundled care, 6-hour bundled care
Other
Lead sponsor
Duke University
Other
Eligibility
Up to 32 Weeks
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Results available

AMBU Bag Manual Ventilation vs. Transport Ventilator Mechanical Ventilation for Transport

NCT06006208
View directory record Official record
Conditions
Oxygenation, Manual Ventilation, Mechanical Ventilation, Point of Care Ultrasound, Cardiac Function Disturbance Postoperative
Interventions
Hamilton C1 ventilator during transport to the ICU
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 23, 2026, 8:19 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial

NCT07293078
View directory record Official record
Conditions
Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure, Acute Kidney Injury, Delirium Confusional State, Shock
Interventions
Point-of-care large language model decision support (ChatGPT-5)
Other
Lead sponsor
MetroWest Artificial Intelligence Research Workgroup
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Framingham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Continuous Glucose Monitoring in the Intensive Care Unit

NCT06190808
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Dexcom G7 Continuous Glucose Monitor
Diagnostic Test
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Sep 23, 2026, 8:19 PM EDT
Completed No phase listed Observational

Study of Sleep and Delirium in the Intensive Care Unit (ICU)

NCT01280097
View directory record Official record
Conditions
Delirium, Sleep Disorders, Circadian Rhythm
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
45 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2015 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional Results available

Feasibility, Acceptability, and Barriers to Implementation of a Geriatrics Bundle in the ICU

NCT04652453
View directory record Official record
Conditions
Intensive Care Unit Syndrome
Interventions
Geriatrics Bundle
Other
Lead sponsor
Yale University
Other
Eligibility
65 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Sep 23, 2026, 8:19 PM EDT
Recruiting Not applicable Interventional

Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit

NCT06000761
View directory record Official record
Conditions
Ventilator Associated Pneumonia, Bronchopulmonary Dysplasia, Respiratory Disease
Interventions
Standardized oral Care
Procedure
Lead sponsor
University of Florida
Other
Eligibility
1 Hour to 3 Days
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 23, 2026, 8:19 PM EDT
Not yet recruiting No phase listed Observational

Prospective Observational Multimodal Neuromonitoring in Adult NSICU Patients

NCT07577713
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic, Cerebral Hemorrhage, Ischemic Stroke, Delayed Emergence From Anesthesia, Encephalopathy
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Pilot Study to Evaluate a Method of Controlling High Blood Sugar in the Pediatric Intensive Care Unit

NCT00240149
View directory record Official record
Conditions
Hyperglycemia
Interventions
Regular Insulin via Insulin-Glucose Algorithm
Drug
Lead sponsor
Stanford University
Other
Eligibility
1 Year to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2007 · Synced Sep 23, 2026, 8:19 PM EDT
Completed Not applicable Interventional

Music Intervention for Agitation Reduction in the Pediatric Intensive Care Unit

NCT03453814
View directory record Official record
Conditions
Critical Illness
Interventions
Music Therapy
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
5 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Sep 23, 2026, 8:19 PM EDT
Terminated Phase 2 Interventional Results available

The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients

NCT00798590
View directory record Official record
Conditions
Critically Ill, Hypoglycemia
Interventions
Glucagon-Like Peptide-1, Saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 23, 2026, 8:19 PM EDT
Active, not recruiting No phase listed Observational

Use of Ultrasonography to Determine Fluid-responsiveness for Shock in a Population of Intensive Care Unit Patients

NCT01680770
View directory record Official record
Conditions
Hypotension
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Sep 23, 2026, 8:19 PM EDT
Completed No phase listed Observational

Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use

NCT04263662
View directory record Official record
Conditions
Mechanical Ventilation, Sedation
Interventions
Analgesia-Sedation algorithm
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 25 Years
Enrollment
680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Sep 23, 2026, 8:19 PM EDT