Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:05 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 135 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Lower Extremity Musculoskeletal Injury Clear all

Conditions: Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear, Patellofemoral Pain
Interventions: eRehab, Formal Physical Therapy; Other
Lead sponsor: Charlotte Sports Medicine Institute, PA; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Prince Frederick, Maryland • Charlotte, North Carolina

Conditions: Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
Interventions: MRI; Diagnostic Test
Lead sponsor: Xiaojuan Li; Other
Eligibility: 18 Years to 50 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Patellar Dislocation
Interventions: Observational; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 13 Years to 90 Years
Enrollment: 201 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Osteoporosis, Achlorhydria, GERD, Hip Fracture
Interventions: Omeprazole; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: Dave Bernholt; Other
Eligibility: 14 Years to 25 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 6
States / cities: Skokie, Illinois • St Louis, Missouri • Durham, North Carolina + 3 more

Conditions: Post-Traumatic Osteoarthritis of Ankle, Ankle Osteoarthritis, Ankle Injuries
Interventions: Osteochondral allograft ankle; Procedure
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 55 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Hip Injuries, Fractures, Hip, Fall Injury, Fall Risk, Osteoporosis, Osteoporosis Risk
Interventions: Tango Belt, Standard of Care (SOC); Device · Other
Lead sponsor: ActiveProtective Technologies, Inc; Industry
Eligibility: 65 Years and older
Enrollment: 471 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 10
States / cities: Sacramento, California • Bensalem, Pennsylvania • Gwynedd, Pennsylvania + 7 more

Conditions: ACL Injury, Anterior Cruciate Ligament Injuries, Musculoskeletal Injury
Interventions: Not listed
Lead sponsor: Sanford Health; Other
Eligibility: 10 Years to 65 Years
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2033
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Knee Injuries, Cartilage, Articular, Gait
Interventions: Real-time gait biofeedback, Sham real-time gait biofeedback; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injuries, Spasticity, Spasm, Muscle Spasticity, Muscle Hypertonia, Muscle Spasm
Interventions: Transcutaneous spinal stimulation at 30 Hz, Transcutaneous spinal stimulation at 75 Hz, Tizanidine, Baclofen, Placebo; Other · Drug
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Jackson, Mississippi

Conditions: Diabetic Foot Ulcers
Interventions: AMNIOEXCEL, Standard of Care, Diabetic Foot Ulcers; Other
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 8
States / cities: Phoenix, Arizona • Castro Valley, California • Stockton, California + 5 more

Conditions: Anterior Cruciate Ligament Injuries
Interventions: Anakinra injection, sterile saline injection; Drug · Procedure
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 35 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Patellofemoral Joint Dislocation, Bicep Tendon Rupture
Interventions: Blood Flow Restriction (BFR) Therapy, Physical Therapy; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Femoral Neck Fractures
Interventions: Hip arthroplasty, Internal fixation; Procedure
Lead sponsor: University of Southern California; Other
Eligibility: 60 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 22
States / cities: Irvine, California • Los Angeles, California • San Francisco, California + 16 more

Conditions: Knee Dislocations, Multiple Ligament Knee Injuries
Interventions: Early Surgery, Delayed Surgery, Early Rehab, Delayed Rehab; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 16 Years to 55 Years
Enrollment: 690 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Muscle Disuse, Muscle Disuse Atrophy
Interventions: 20 grams protein, 40 grams protein; Dietary Supplement
Lead sponsor: United States Army Research Institute of Environmental Medicine; Federal
Eligibility: 17 Years to 39 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Natick, Massachusetts

Conditions: Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot, Diabetes Complications, Peripheral Neuropathy
Interventions: Peer counseling group; Behavioral
Lead sponsor: Casa Colina Hospital and Centers for Healthcare; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 3
States / cities: Downey, California • Los Angeles, California • Pomona, California

Conditions: Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions: Carbon Fiber Custom Dynamic Orthosis (CDO); Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions: Medial Patellofemoral Ligament (MPFL) Reconstruction; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 10 Years to 35 Years
Enrollment: 850 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 16
States / cities: Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more

Conditions: Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
Interventions: Accelerated Flap Coverage Surgery, Standard of Care Flap Timing; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 356 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 7
States / cities: Sacramento, California • Baltimore, Maryland • Largo, Maryland + 2 more

Conditions: Lower Extremity Problem, Musculoskeletal Injury
Interventions: Not listed
Lead sponsor: MultiCare Health System Research Institute; Other
Eligibility: 13 Years to 25 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Puyallup, Washington

Conditions: Hallux Limitus
Interventions: Metatarsophalangeal Extension Dynasplint System, Standard of Care; Device · Other
Lead sponsor: Dynasplint Systems, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 2
States / cities: Jonesboro, Georgia • Marietta, Georgia

Conditions: Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
Interventions: Accuro XV Ultrasound Imaging System; Device
Lead sponsor: Rivanna Medical, Inc.; Industry
Eligibility: 5 Years and older
Enrollment: 25,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 10
States / cities: San Francisco, California • Denver, Colorado • New Haven, Connecticut + 7 more

Conditions: Medial Tibial Stress Syndrome
Interventions: Resistance Training; Other
Lead sponsor: Rowan University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Glassboro, New Jersey

Search by objective public record fields.

Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

The Impact of Tibial Tubercle-trochlear Groove Distance and Patellar Height on the Outcome of Isolated Medial Patellofemoral Ligament Reconstruction

Does Omeprazole Decrease Intestinal Calcium Absorption?

Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction

Indications for Osteochondral Allograft Transplantation

Mitigation of Major Hip Injury Due to Fall With a Smart Belt

Baseline ACL Injury Risk Screening and Normative Data

Optimizing Gait Biomechanics for Posttraumatic Osteoarthritis Prevention

Electrical Neuromodulation for Modifying Spinal Network Involved in Spasticity

Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers

Biologic Therapy to Prevent Osteoarthritis After ACL Injury

BFR After Biceps Tendon Repair and MPFLR

MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

STaR Trial: Multiple Ligament Knee Injuries

Muscle Response to Different Amounts of Dietary Protein During Leg Immobilization

Peer Support for Patients With Diabetic Foot Ulcers

Custom Dynamic Orthoses to Reduce Articular Contact Stress

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

Accelerated Flap Coverage in Severe Lower Extremity Trauma

Adolescent Normative Sport Movement Analysis

Hallux Limitus Treated With Dynamic Splinting: A Randomized, Controlled Trial

Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms

Medial Tibial Stress Syndrome Prevention