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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Maternal Complications Clear all
Completed Not applicable Interventional

A RCT of CenteringPregnancy on Birth Outcomes and Maternal Inflammation

NCT04097548
View directory record Official record
Conditions
Preterm Birth
Interventions
CenteringPregnancy
Behavioral
Lead sponsor
Endeavor Health
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
1,133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Jul 22, 2026, 8:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Melanated Group Midwifery Care (MGMC)

NCT05365815
View directory record Official record
Conditions
Pregnancy Complications, Maternal Care Patterns, Patient Engagement
Interventions
Melanated Group Midwifery Care
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
15 Years to 49 Years · Female only
Enrollment
432 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jul 22, 2026, 8:18 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Prenatal Aspirin and Postpartum Vascular Function

NCT05653973
View directory record Official record
Conditions
Preeclampsia, Microvascular Function
Interventions
Acetylcholine, Endothelin-1
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Jul 22, 2026, 8:18 PM EDT
Withdrawn Not applicable Interventional

Pacifiers and Breastfeeding Among Mothers at Risk for Postpartum Depression

NCT03709004
View directory record Official record
Conditions
Breastfeeding, Postpartum Depression
Interventions
Pacifier
Other
Lead sponsor
University of California, Davis
Other
Eligibility
12 Hours to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Jul 22, 2026, 8:18 PM EDT
Completed Not applicable Interventional

Advancing Health Equity by Integrating Social-Clinical Models During Pregnancy

NCT06311799
View directory record Official record
Conditions
Cardiovascular Diseases, Obesity, Maternal, Diabetes
Interventions
WIC Referral, RDN Referral
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Jul 22, 2026, 8:18 PM EDT
Active, not recruiting Not applicable Interventional

Living Healthy for Moms RCT

NCT06666400
View directory record Official record
Conditions
Postpartum Depression (PPD), Cardiac Event
Interventions
LHMoms Intervention, No intervention
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
4
States / cities
Brooklyn, New York • Jamaica, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Jul 22, 2026, 8:18 PM EDT
Enrolling by invitation No phase listed Observational

EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 2)

NCT06148532
View directory record Official record
Conditions
Maternal Sepsis, Infections
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
400,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 22, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development, Feasibility and Acceptability of Fathers and Babies (FAB): A Pilot Study

NCT03427528
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression, Depression
Interventions
Fathers and Babies (FAB), MB 1-on-1 plus TXT
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 17, 2022 · Synced Jul 22, 2026, 8:18 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Maternal Newborn Health Registry

NCT01073475
View directory record Official record
Conditions
Pregnancy Outcome Trends in Low-resource Geographic Areas
Interventions
There is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
Other
Lead sponsor
NICHD Global Network for Women's and Children's Health
Network
Eligibility
Not listed
Enrollment
950,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2030
U.S. locations
8
States / cities
Birmingham, Alabama • Aurora, Colorado • Indianapolis, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 22, 2026, 8:18 PM EDT
Completed Phase 1 Interventional

A Study to Evaluate the Safety and Tolerance of Combination Anti-HIV Drug Therapy (Indinavir, Lamivudine, and Zidovudine) in HIV-Positive Pregnant Women and Their Infants

NCT00000944
View directory record Official record
Conditions
HIV Infections, Pregnancy
Interventions
Indinavir sulfate, Lamivudine, Zidovudine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2003
U.S. locations
4
States / cities
San Francisco, California • Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Jul 22, 2026, 8:18 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study)

NCT00865683
View directory record Official record
Conditions
Overweight and Obesity, Insulin Resistance, Diabetes, Gestational, Hypertension in Pregnancy, Pre-Eclampsia
Interventions
DHA Supplements, Placebo Supplements
Dietary Supplement
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 40 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2009 · Synced Jul 22, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementation of the NPMS Obstetric Hemorrhage Bundle at a Tertiary Center: Utilization of the Delphi Method

NCT03018119
View directory record Official record
Conditions
Pregnancy Hemorrhage, Postpartum Hemorrhage
Interventions
Survey
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jul 22, 2026, 8:18 PM EDT
Recruiting Not applicable Interventional

Nutrition Optimization and Community Upliftment for Postpartum Recovery

NCT06445530
View directory record Official record
Conditions
Obesity, Maternal, Gestational Diabetes
Interventions
MFeast ENHANCED, MFeast Usual Care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Jul 22, 2026, 8:18 PM EDT
Completed Phase 3 Interventional

A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)

NCT00000751
View directory record Official record
Conditions
HIV Infections, Pregnancy
Interventions
Anti-HIV Immune Serum Globulin (Human), Globulin, Immune, Zidovudine
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
13 Years to 60 Years · Female only
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
48
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2008 · Synced Jul 22, 2026, 8:18 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Curio Digital Therapy for the Treatment of Post-partum Depression

NCT05958095
View directory record Official record
Conditions
PostPartum Depression
Interventions
MamaLift Plus, Digital Sham App
Device
Lead sponsor
Healthcare Innovation Technology Lab
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Jul 22, 2026, 8:18 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy

NCT03809572
View directory record Official record
Conditions
Maternal Psychological Distress, Postpartum Depression, Prenatal Stress
Interventions
Mindfulness Based Cognitive Therapy
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Jul 22, 2026, 8:18 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Rapid HIV Tests for Women Late in Pregnancy and During Labor

NCT00046436
View directory record Official record
Conditions
HIV Infections
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older · Female only
Enrollment
7,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2004
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2013 · Synced Jul 22, 2026, 8:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Health Diabetes Prevention Study

NCT05343494
View directory record Official record
Conditions
Gestational Diabetes, PreDiabetes, Hyperglycemia, Glucose Intolerance During Pregnancy
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Jul 22, 2026, 8:18 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Study of Chlorhexidine in the Prevention of HIV-1 Transmission From Mothers to Their Babies

NCT00006075
View directory record Official record
Conditions
HIV Infections
Interventions
Chlorhexidine gluconate
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2007
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 29, 2008 · Synced Jul 22, 2026, 8:18 PM EDT
Completed No phase listed Observational

Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension

NCT05881252
View directory record Official record
Conditions
Maternal Hypertension
Interventions
Clinical blood pressure threshold of SBP >= 160 mmHg for acute treatment of hypertension, Clinical blood pressure threshold of SBP >= 180 mmHg for acute treatment of hypertension
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Female only
Enrollment
1,003 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Jul 22, 2026, 8:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Maternal Oxygen Supplementation for Intrauterine Resuscitation

NCT05681624
View directory record Official record
Conditions
Fetal Distress, Fetal Hypoxia, Labor and Delivery Complication
Interventions
Maternal oxygen supplementation, Room air
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
2,124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 22, 2026, 8:18 PM EDT
Withdrawn Not applicable Interventional

Nutrition Optimization and Community Upliftment for Postpartum Recovery: Hypertension

NCT06445543
View directory record Official record
Conditions
Obesity, Maternal, Pre-Eclampsia; Complicating Pregnancy, Gestational Hypertension, Eclampsia; Complicating Pregnancy
Interventions
MFeast ENHANCED, MFeast Usual Care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jul 22, 2026, 8:18 PM EDT
Withdrawn Early Phase 1 Interventional

Evaluating Pyrroloquinoline Quinone (PQQ) for Improving Obese Pregnancy Outcomes

NCT06245083
View directory record Official record
Conditions
Maternal Obesity
Interventions
Pyrroloquinoline quinone (PQQ), Placebo with soybean oil
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Jul 22, 2026, 8:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mother Sibling Interactions Following Very Low Birth Weight (VLBW) Infant Homecoming

NCT01385254
View directory record Official record
Conditions
Very Low Birthweight
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Up to 4 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Durham, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Jul 22, 2026, 8:18 PM EDT