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ClinicalTrials.gov public records Last synced May 22, 2026, 1:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 135 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Middle Aged Clear all
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Depression, Melancholia
Interventions
Sertraline, Nortriptyline
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years to 95 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2002
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2015 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Chronic Pain
Interventions
Chronic Disease Self-Management Program (CDSMP) for chronic pain in Spanish, Remote feedback active group, Remote feedback control group
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
40 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 30, 2022 · Synced May 22, 2026, 1:33 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Hypertension, Aging, Endothelial Dysfunction, Men
Interventions
Blueberry Powder, Placebo Powder
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
45 Years to 70 Years · Male only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced May 22, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Sedentary Middle Age and Older Aged Adults
Interventions
RemoteEx+ Programming
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
40 Years to 85 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Emporia, Kansas • Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Meditation, Control Group
Interventions
Calm Meditation, Educational Podcast Control
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
40 Years to 64 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced May 22, 2026, 1:33 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aging
Interventions
Pegboard practice, Force control practice
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years to 89 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced May 22, 2026, 1:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Effects of Chemotherapy
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
11 Years to 50 Years · Female only
Enrollment
391 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2020
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Radnor, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced May 22, 2026, 1:33 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
Moderate Intensity Exercise (one day), Placebo - Light Intensity Exercise (one day), Moderate Intensity Exercise (9 wks), Day 1 Assessments, Symptom Measures and Neuropsychological Tests, Day 36 Assessments, Day 57 Assessments, Day 78 Assessments
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
40 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Reading Problem
Interventions
Newsletter using a virtual mode of delivery
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 13 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Dietary Habits
Interventions
Coached
Behavioral
Lead sponsor
Florida Atlantic University
Other
Eligibility
45 Years to 64 Years · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Dec 8, 2020 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
HIV, Cognition - Other, Impaired Driving
Interventions
Speed of Processing Training, Internet Navigational
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 6, 2021 · Synced May 22, 2026, 1:33 AM EDT
Not yet recruiting Early Phase 1 Interventional
View directory record Official record
Conditions
HIV (Human Immunodeficiency Virus)
Interventions
Standard Smell Training Group, Overnight Diffuser Grou
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Body Weight Changes
Interventions
Videos, Action Plans, Discussion Boards, Health behavior tracking
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
40 Years to 64 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Auburn, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aging, Blood Pressure, Arterial Stiffness
Interventions
Coconut Sap Powder (CSP), Placebo
Dietary Supplement
Lead sponsor
Ball State University
Other
Eligibility
40 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Muncie, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 11, 2022 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aging
Interventions
MitoQ, Placebo
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
60 Years to 79 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 11, 2018 · Synced May 22, 2026, 1:33 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Chronic Pain, Depression
Interventions
Relief-Hybrid
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
New York, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Alzheimer's Disease, Aging
Interventions
Enhanced Physical Activity
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aging, Menopause, Healthy
Interventions
Red cabbage microgreens, Red beet microgreens
Other
Lead sponsor
Colorado State University
Other
Eligibility
45 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aging
Interventions
Probiotic - Lactobacillus Rhamnosus GG, Placebo
Dietary Supplement · Other
Lead sponsor
Kent State University
Other
Eligibility
55 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced May 22, 2026, 1:33 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
[C-11], Pittsburgh Compound B
Radiation · Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
40 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Exercise, Gait, Cognitive Decline, Caregiver Burden, Cognitive Impairment, Dementia, Alzheimer Disease, Mild Cognitive Impairment, Respite Care, Mental Health, Depression, Music Therapy, Psychosocial Intervention, Cognition, Geriatric Assessment, Cognitive Dysfunction, Cognitive Aging, Outcome Assessment, Health Care, Balance, Fall, Walking, Affect, Physical Exertion, Memory Deficit, Memory Disorders, Memory Impairment, Neuropsychological Tests, Executive Function, Middle Aged, Healthy Aging, Elderly
Interventions
Group exercise program
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
55 Years to 99 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Obesity, Vascular Dementia, Cognitive Impairment
Interventions
Urolithin A, Placebo
Dietary Supplement · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
40 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced May 22, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Cardiovascular Diseases in Old Age, Aging, Cardiovascular Diseases, Sleep
Interventions
Ketone Ester, Placebo
Dietary Supplement
Lead sponsor
Georgia Southern University
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced May 22, 2026, 1:33 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Tamsulosin and avanafil, Doxazosin and avanafil
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
40 Years to 65 Years · Male only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 6, 2011 · Synced May 22, 2026, 1:33 AM EDT